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실내 위치 측위를 통한 D2D 통신 성공 확률 (Opportunity Probability) 측정 및 예측
한규원(Kyuwon Han),남혜린(Hyelin Nam),박지훈(Jihoon Park),성명훈(Meonghoon Seong),김성륜(Seong-Lyun Kim) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2
본 논문에서는 실내 측위를 진행하고, 그 결과를 바탕으로 D2D 통신 성공 확률인 Opportunity probability (OP)를 예측 및 측정하여 그 값을 비교하는 실험을 소개한다. 실내 측위를 위해서 스마트폰의 관성 측위 센서와 이를 보정하기 위한 딥러닝 네트워크, 그리고 WiFi RTT를 융합한 측위 기법이 사용되었다. 그 결과 OP값을 중위값 90% 이상으로 예측하는 데 성공하였다.
엽산 투여에 의한 니코틴-유도 혈장 homocysteine 농도에 대한 영향과 금단증상 완화를 위한 한의학적 처방에 대한 고찰
박영철,신헌태,박해모,이선동,Park, Yeong-Chul,Shin, Heon-Tae,Park, Hae-Mo,Lee, Sun-Dong 대한예방한의학회 2007 대한예방한의학회지 Vol.11 No.1
Homocysteine is a sulfur amino-acid produced during the metabolism of the essential amino acid methionine. Moderately increased plasma total homocysteine concentration have been implicated as a risk factor for occlusive vascular disease. Smoking is known to be one of the most significant factors leading to elevated plasma homocysteine concentration. However, the main component of a cigarette, nicotine has been not studied whether it is linked directly to the increase of homocysteine concentration in blood. The metabolism of homocysteine is closely linked to that of its cofactors, folate. Here, the effects of nicotine and folic acid on amount of plasma homocysteine were studied. The concentration of homocysteine was increased by about 70% in rat plasma after nicotine treatment for one month. This increased concentration of homocysteine was reduced by about 60% at 6 hours later after folate treatment. Thus, nicotine should be directly involved in increasing the concentration of plasma homocysteine. Also it is suggested that these results can be and applied and used for controlling withdrawal symptoms after stopping smoking as one of oriental medicine formulas.
배양망막색소상피세포에서 젤라틴아제의 발현에 대한 산화스트레스의 영향
박영철,최광주,Young-Chul Park,Gwang-Ju Choi 대한안과학회 2005 대한안과학회지 Vol.46 No.11
Purpose: To evaluate the expression pattern of gelatinases in the human retinal pigment epithelial cell line ARPE-19 in response to oxidative stress. Methods: ARPE-19 cells were exposed to paraquat for 72 hours. The cells were assayed for the mRNA expression of gelatinase A and gelatinase B by reverse transcriptase polymerase chain reaction (RT-PCR). The conditioned media were assayed for the production of gelatinases protein by Western blotting. Also, the inhibitory effect of the antioxidants against oxidative stress to the cells was evaluated. Results: The gelatinase levels in the RPE cells increased under oxidative stress compaired with the control (p〈 0.05). Also, the levels decreased when the cells were incubated with the antioxidant N-acetylcysteine (NAC). Conclusions: Oxidative stress upregulates gelatinase expression in ARPE-19 cells.
숙지황(Rehmannia glutinosa)의 약리작용과 독성
박영철,이기용,백낙민,손혜영,국윤범,이선동,Park, Yeong-Chul,Lee, Gi-Yong,Baek, Lag-Min,Son, Hye-Young,Kook, Yoon-Boom,Lee, Sun-Dong 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1
Objectives : Rehmannia glutinosa has been used extensively in Korean traditional medicine. Although thorough clinical trials are lacking, Various pharmacological actions for Rehmannia glutinosa has been identified newly using animal models. In addition, it was reported that reactive intermediates, potentially causing toxic effects, was isolated from one of components in Rehmannia glutinosa. In this article, it is purposed for explanation and introduction of new studies for Rehmannia glutinosa in terms of pharmacological action and toxicology. Methods : New studies for Rehmannia glutinosa were reviewed and summarized in terms of pharmacological action and toxicity. Results and Conclusions : Rhmannia glutinosa and its components including iridoids, saccharides, as well as amino acid, showed a variety of pharmacological actions on the blood system, immune system, endocrine system, cardiovascular system and the nervous system. In addition, it was identified that aucubin, one of major components of Rhmannia glutinosa was biotransformed to reactive intermediates by ${\beta}$-glycosidase and acid-hydrolysis, resulting in forming aucubigenin- albumin adduct. Even if a lot of new pharmacological actions has been identified, it should be considered for Rhmannia glutinosa to contain the material producing reactive intermediates which may induce the side effects.
박영철,임종빈,박정선,Park, Young Chul,Im, Jong Bin,Park, Jung Sun 항공우주시스템공학회 2007 항공우주시스템공학회지 Vol.1 No.2
The Damage Tolerant Design is developed to help alleviate structural failure and cracking problems in aerospace structures. Recently, the Damage Tolerant Design is required and recommended for most of aircraft design. In this paper, the damage tolerant design is applied to tilt rotor UAV. First of all, the fatigue load spectrum for the tilt rotor UAV is developed and fatigue analysis is performed for the flaperon joint which has FCL (fatigue critical location). Tilt rotor UAV has two modes: helicopter mode when UAV is taking off and landing; fixed wing mode when the tilt rotor UAV is cruising. To make fatigue load spectrum, FELIX is used for helicopter mode. TWIST is used for fixed wing mode. Fatigue analysis of flaperon joint is performed using fatigue load spectrum. E-N curve approach is used for picking crack initiation point. The LEFM(Linear Elastic Fracture Method) is considered for analyzing crack growth or propagation. Finally, including the crack initiation and propagation, the fatigue life is evaluated. Therefore the Damage Tolerant Design can be done.
세라믹/금속접합재의 고온 열사이클에 따른 잔류응력분포 및 굽힘강도 특성
박영철,허선철,부명환,김현수,강재욱,Park, Young-Chul,Hue, Sun-Chul,Boo, Myoung-Hwan,Kim, Hyun-Su,Kang, Jae-Wook 대한기계학회 1997 大韓機械學會論文集A Vol.21 No.10
Since the ceramic/metal joint material is made at a high temperature, the residual stress develops when it is cooled from bonding temperature to room temperature due to remarkable difference of thermal expansion coefficient between ceramic and metal. As residual stress at ceramic/metal joints influences the strength of joints, it is important to estimate residual stress quantitatively. In this study, it is attempted to estimate joint residual stress of Si$_3$N$_4$STS304 joints quantitatively and to compare the strength of joints. The difference of residual stress is measured when repeated thermal cycl is loaded, under the conditions of the practical use of the ceramic/metal joint. The residual stress increases at 1 cycle of thermal load but decreases in 3 cycles to 10 cycles of thermal load. And 4-point bending test is performed to examine the influence of residual stress on fracture strength. As a result, it is known that the stress of joint decreases as the number of thermal cycle increases.
박영철,오영택,MOON-HEE SUNG,Hong-Gyu Park,김태진,조치흠,박종섭,이재관 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.6
Objective: Persistent infection of HPV increases the chance of carcinoma in situ of cervixthrough stages of cervical intraepithelial neoplasia (CIN) 1, 2, and 3, and finally progressesinto cervical cancer. We aimed to explore the safety and efficacy of BLS-M07 which is orallyadministered agent expressing human papillomavirus (HPV) 16 E7 antigen on the surface ofLactobacillus casei in patients with CIN 3. Methods: Patients with CIN 3 were recruited in our clinical trial. Reid Colposcopic Index(RCI) grading and serum HPV16 E7 specific antibody production were used to evaluateefficacy of BLS-M07. In phase 1, BLS-M07 was administered orally, 5 times a week, on weeks1, 2, 4, and 8 with dosages of 500 mg, 1,000 mg, and 1,500 mg. In phase 2a, patients weretreated with 1,000 mg. The primary endpoints were the safety and the pathologic regressionon colposcopic biopsy. Results: Nineteen patients were enrolled in the CIN 3 cohort. In phase 1, no patientsexperienced dose limiting toxicity. No grade 3 or 4 treatment-related adverse events or deathswere observed. At 16 weeks after treatment, RCI grading was improved and serum HPV16E7 specific antibody production increased (p<0.05). Six of 8 (75%) patients with CIN 3 werecured in phase 2a. Conclusions: Oral immunization with BLS-M07 increases production of serum HPV16 E7specific antibody which induces protective humoral immunity. The safety of this oral vaccinewas proved and could be a competitive non-surgical therapeutic agent of CIN 3. Trial Registration: ClinicalTrials.gov Identifier: NCT02195089
박영철,Park, Yeong-Cheol 한국건강관리협회 1988 건강소식 Vol.12 No.2
스트레스의 극복을 위해서는 규칙적 운동, 정신적ㆍ신체적 휴식, 술, 담배를 끊음으로서 신체적 탄력과 적응력을 고양시켜주어야 한다.