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문준웅,이진학,Jun-Woong Moon,Jin-Hak Lee 대한안과학회 2005 대한안과학회지 Vol.46 No.5
Purpose: To investigate risk factors for the progression of age-related incipient cataract. Methods: Among patients who visited the authors’ clinic (SNUH) from Jun 2002 to Jan 2003 for age-related incipient cataract, those meeting one of the following two criteria were recruited: 1) non-progressive group: BCVA (best corrected visual acuity) decrease by two lines or less for 5 years or more according to Snellen’s chart, 2) progressive group: BCVA decrease by four lines or more in 5 years or less. Age, sex, regular exercise, smoking, drinking, anti-cataract eyedrops, duration of menopause, hormone replacement therapy, weight, height, and BMI (body mass index) were investigated by questionnaire and compared between the two groups. If both eyes met the eligibility criteria, one eye was randomly selected. Results: There were not statistically significant differences regarding age, sex, anti-cataract eyedrops application, regular exercise, duration of menopause and hormone replacement therapy, smoking, drinking, weight, and height. However, the mean BMI of the progressive group was significantly higher than that of the non-progressive group (p=0.041, Student t-test). Conclusions: In patients with age-related incipient cataract, high BMI may be related to more rapid progression of incipient cataract, thus resulting in faster visual loss.
베체트 포도막염에 대한 타크로리무스(Tacrolimus)의 단기 효과와 합병증
문준웅,송수정,구보경,조영민,유형곤,Jun Woong Moon,Su Jeong Song,Bo Kyung Koo,Young Min Cho,Hyeong Gon Yu 대한안과학회 2007 대한안과학회지 Vol.48 No.12
Purpose: To investigate the clinical effects and side effects of Tacrolimus for ocular Beh?et`s disease. Methods: Eight patients (male: 5, age: 35±7.5 (25-48) years) with Beh?et`s uveitis, refractory posterior uveitis unresponsive to combination treatment with cyclosporine, azathioprine, and oral steroid or significant cyclosporine-related adverse effects were recruited prospectively, and cyclosporine was switched to Tacrolimus. Visual acuity, degree of anterior chamber, and vitreous haze were compared before the conversion and three months after. Oral glucose tolerance, plasma insulin, cholesterol, creatinine, and aspartate (AST)/alanine aminotransferase (ALT) were measured to monitor systemic effects. Results: Visual acuity did not change significantly after conversion to Tacrolimus. Anterior chamber (seven patients) and vitreous (four patients) inflammation were found before conversion and decreased or disappeared after conversion. Overall plasma levels of glucose, insulin, creatinine, and AST/ALT were similar before and after conversion. However, cholesterol was significantly decreased after conversion (p=0.028). One patient developed diabetes mellitus. Conclusions: Tacrolimus may be effective for Beh?et`s uveitis unresponsive to or intolerable of traditional treatments. In addition, periodic monitoring for side effects, such as hyperglycemia and diabetes mellitus, may be necessary.
유리체 절제술에서 점안 마취와 자가조절정맥마취의 병합효과
문준웅,임영진,정흠,유형곤 대한안과학회 2005 대한안과학회지 Vol.46 No.5
Purpose: To investigate the effects of topical anesthesia combined with patient-controlled sedation analgesia for posterior vitrectomy. Methods: All patients requiring vitrectomy from December 2003 to January 2004 at Seoul National University Hospital underwent surgery with topical anesthesia combined with patient-controlled sedation analgesia. The levels of intraoperative pain and sedation were recorded. The associations of operation time, combined vitreoretinal procedures, and age with intraoperative pain were investigated. Hemodynamic instability and respiratory depression were checked throughout the operation. Results: Forty-three patients (53 eyes) underwent vitrectomy under topical anesthesia combined with patient-controlled sedation analgesia. The mean age was 51.75±13.68 years and the sex ratio was 25:28 (male:female). The mean of VAS (visual analogue scale) was 53.61 (5~67). The level of intraoperative sedation was grade 1 (64%) or 2 (36%). No anesthesia-associated complications were found. Conclusions: In spite of relatively high VAS, there were no remarkable difficulties in performing posterior vitrectomy and appropriate levels of intraoperative sedation and cooperation were available without anesthesia-associated complications.
문준웅,김성준,장봉린,.Jun-Woong Moon. M.D... Sung-Jun Kim. M.D... Bong-Leen Chang. M.D.. 대한안과학회 2005 대한안과학회지 Vol.46 No.8
Purpose: To report the clinical experience and surgical results of modified transposition surgery, in which half-width tendons are isolated and sutured into the paralyzed extraocular muscle. Methods: We retrospectively reviewed the medical records of 6 patients (7 eyes), who had undergone modified transposition surgery to correct severe limitation of eye movement from January 1996 to December 2001. First, we divided the half-width tendons of two rectus muscles adjacent to the paralyzed rectus muscle and disinserted the halves from the sclera. The two half-width tendons were positioned underneath of the scleral insertion of the paralyzed muscle, sutured together and then sutured to the paralyzed muscle. In the case of contracture of the antagonizing extraocular muscle, recession of the antagonist was performed. Results: Five of the six patients showed deviation under 15 prism diopters at primary gaze at distance, while synergistic divergence recurred in the sixth patient. Conclusions: Modified transposition surgery as described in this paper is thought to be an effective and safe method for correction of paralytic strabismus.
문준웅,황정민-,Jun Woong Moon Jeong-Min Hwang- 대한안과학회 2006 대한안과학회지 Vol.47 No.1
Purpose: To report a case of congenital symblepharon associated with No. 3 craniofacial cleft. Methods: A 40-month old girl with left eyelid lesion underwent an ophthalmologic examination at the department of ophthalmology and a face examination at the department of plastic and reconstructive surgery. Results: Congenital symblepharon associated with No. 3 craniofacial cleft including bifid uvula, partial cleft lip, and coloboma of the lower medial eyelid was found. She did not have amblyopia or strabismus. A MEDLINE search of the literature revealed only one reported case of symblepharon associated with a craniofacial cleft.