http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 문명희 (검색결과 58 건)
- 무료
- 기관 내 무료
- 유료
-
Phospholipid Analysis by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry
문명희 사단법인 한국질량분석학회 2014 Mass spectrometry letters Vol.5 No.1
Lipids play important roles in biological systems; they store energy, play a structural role in the cell membrane, and areinvolved in cell growth, signal transduction, and apoptosis. Phospholipids (PLs) in particular have received attention in the medical andlipidomics research fields because of their involvement in human diseases such as diabetes, obesity, atherosclerosis, and many cancersassociated with lipid metabolic disorders. Here I review experimental strategies for PL analysis based on nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry (nLC-ESI-MSn). In particular, discussed are lipid extraction methods, nanoflowLC separation of PLs, effect of ionization modifiers on the ESI of PLs, influence of chain lengths and unsaturation degree of acyl chainsof PLs on MS intensity, structural determination of the molecular structure of PLs and their oxidized products, and quantitative profilingof PLs from biological samples such as tissue, urine, and plasma in relation to cancer and coronary artery disease.
-
-
다문화 그림책을 활용한 교육활동이 유아의 편견과 친사회적 행동에 미치는 효과
문명희 한국영유아교원교육학회 2014 유아교육학논집 Vol.18 No.4
본 연구의 목적은 다문화 그림책을 활용한 교육활동이 유아의 편견과 친사회적 행동에 미치는 효과를 알아보고자 하였다. 연구대상은 경기도 D구에 소재한 S병설유치원에 재학 중인 만 5세 유아 27명씩으로 실험집단과 통제집단으로 무선 배정하고 총 8주 동안 진행되었다. 활동을 실시 한 후 효과를 분석하기 위해 t검증을 실시하였다. 그 결과, 다문화 그림책을 활용한 교육활동은 유아의 편견감소에 긍정적인 영향을 미쳤으며, 특히 외모, 장애, 가족구성에 대한 편견 감소에 효과적이었다. 또한 다문화 그림책을 활용한 교육활동은 유아의 친사회적 행동의 증진에 긍정적인 영향을 미쳤으며, 지도성, 도움주기, 의사소통, 주도적 배려, 접근 시도하기, 나누기, 감정이입 및 조절 능력의 증진에 효과적이었다. 본 연구 결과는 유아들이 참여하는 다문화 그림책을 활용한 교육활동이 유아의 편견과 친사회적 행동의 증진에 효과적인 교수-학습 접근법임을 시사하고 있다. The purpose of this study was to examine Educational Activities with Multicultural Picture Books on Young Children's Prejudice and Prosocial Behavior. The research subjects are 5-year-old children who had been examined for 8 weeks from 16th, October to 7th, December, 2012: fifty-four 5-year-old children from S public kindergarten, D-gu in Gyeonggi-do were an experimental group and in the same kindergarten were a control group. The collected data were analyzed by SPSS 12.0 Windows program. The research results are as follows: the educational activities with multicultural picture books had a positive effect on prejudice reduction of infants. In addition, it was especially effective in prejudice reduction of appearance, disability, family composition. Also, the educational activities with multicultural picture books had a positive effect on the increase of prosocial behavior of infants. Moreover, it was especially effective in the increase of leadership, helping others, communication, thoughtful consideration, empathy, controlling emotion and so on than the other. These reseach results imply that the educational activities with multicultural picture books that infants participated in is an effective teaching-learning approach in the increase of prejudice reduction and prosocial behavior.
-
-
문명희,박상열,정재교,Jae-Suk Seo,설재원,이유진,Meilang Xue,Christopher J. Jackson 생화학분자생물학회 2011 Experimental and molecular medicine Vol.43 No.3
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily of cytokines, is one of the most promising candidates for cancer therapeutics. However, many osteosarcomas are resistant to TRAIL. Bisphosphonates are very effective in the treatment of bone problems associated with malignancies; the antitumor effects are due to the inhibition of protein prenylation that is essential for cell function and survival. The purpose of this study was to determine the effects of bisphosphonates on TRAIL-resistant MG 63 human osteosarcoma cells. The cells showed no response to TRAIL alone; however,pre-treatment with bisphosphonates significantly increased TRAIL-mediated apoptosis and cellular activation of caspase-3. Bisphosphonates significantly induced mRNA and protein expression of the TRAIL receptor, DR5. Bisphosphonates induced protein unprenylation in MG 63 cells; in addition, co-treatment with TRAIL also significantly increased protein unprenylation. Blocking of protein unprenylation using geranylgeraniol attenuated the cellular responses,including cell apoptosis and protein unprenylation induced by bisphosphonates and TRAIL. This is the first study to demonstrate that bisphosphonates markedly enhanced TRAIL-induced apoptosis in human osteosarcoma cells. These findings suggest that bisphosphonates may be a new and effective anticancer treatment with TRAIL proteins for TRAIL-resistant cancer cells.
-
-
아들의 암 투병 과정에서 미술작업이 주는 구원에 대한 경험 탐구
문명희,최선남 한국미술치료학회 2022 美術治療硏究 Vol.29 No.5
본 탐구는 탐구자의 아들이 암 투병을 하는 기간 중에 탐구자가 미술작업을 수행하면서 얻은 구원에 대한 경험에 대해 이야기하고 그 경험의 의미는 무엇인지를 서술한 것이다. 이를 위하여 탐구자는 질적 연구의 한 방법인 내러티브 탐구(Narrative inquiry)를 사용하여 미술작업이 어떻게 자신의 구원에 이르렀는지 생생하게 드러내고자 노력하였다. 탐구에는 2021년 1월부터 2021년 8월까지 탐구자가 아들의 병을 간호하던 시기에 작업했던 미술작품과 사진, 기록한 글들을 정리하였으며, 2022년 4월 12일 박사과정의 사례세미나에 이를 발표하였다. 사례세미나 발표 후 동료 미술치료사들의 반응작업을 통한 그림, 인터뷰에서 생성된 축어록, 질문지 및 면담자료 역시 포함하여 글쓰기가 이루어졌다. 탐구의 과정에서 새로운 매체와의 만남, 작업 몰입의 즐거움 및 미술작품의 완성을 통해 내면의 불안과 혼란이 희망으로 변환되는 경험을 하였다. 이울러 동료 미술치료사들의 이해와 공감은 자기돌봄의 큰 힘이 되며, 또한 미술작업은 자기돌봄을 위한 선물임을 깨닫게 되었다. 미술작업이 주는 구원은 미술치료사를 창조적 원천에 연결되게 하며, 동료 미술치료사들의 지지는 또 다른 자기돌봄 경험이 되었다. 이러한 내용을 바탕으로 본 연구의 의의와 제한점에 대하여 논의하였다.
-
한복지 태의 계량화(II) -지능시스템에 의한 태의 판정-
문명희,최석철,박정환 한국섬유공학회 2002 한국섬유공학회지 Vol.39 No.4
In this paper, an attempt to quantify hands of fabrics for Korean folk clothes has been made based on mechanical properties and the sensory test using artificial intelligence systems. In order to classify the primary hand values, four neural networks with three-layered structure were constructed and one neural network was constructed to classify the total hand value. The learning algorithm was selected with the error back propagation algorithm and, in order to reduce errors and to speed up learning, the moment method was selected. From the analysis of the primary and total hands using a self-constructed artificial intelligence system, the error rates of silky, sleekness, roughness, and stiffness compared with the judgements of expert panels were found to be 4.9%, 4.9%, 4.9%, and 1.6%, respectively, while that of the total hand was 9.83%.
-
-
인센티브 여행 참가자의심리적 체험이 직무성과에 미치는 영향 연구
문명희,이미혜 한국관광학회 2009 관광학연구 Vol.33 No.3
This study was conducted to identify psychological experience that the incentive trip participants have had while traveling a certain area and the impact on the organizational job performance and psychological experience in terms of the incentive trip participation program. Many countries have been utilizing the incentive trip participation program as a means of motivation in order to achieve the objective of organization. In the result of the study, the psychological experience was classified with three factors. It was shown that these factors had a positive impact on the organizational job performance as well as the personal job performance.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
