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허혈로 유발된 토끼의 급성 신부전에 대한 甘草(감초) 약침액 정맥 주입의 영향
김형철,김경호,이금산,김형우,임세현,임지연,김영균,조수인,Kim, Hyeong-Cheol,Kim, Gyoung-Ho,Lee, Guem-San,Kim, Hyung-Woo,Lim, Se-Hyun,Lim, Chi-Yeon,Kim, Young-Gyun,Cho, Su-In 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.4
Objectives: The present study was undergone to determine whether Glycyrrhizae Radix pharmacopuncture intravenous injection exerts beneficial effect against the ischemia-induced acute renal failure in rabbits. Methods: Rabbits were treated with Glycyrrhizae Radix pharmacopuncture via i.v., followed by renal ischemia/reperfusion. The fractional excretion of glucose and phosphate were measured and the malondialdehyde content was also determined. The morphological changes of cortical part of kidney also observed with light microscope. Results: Renal ischemia/reperfusion caused increase of the fractional excretion of glucose and phosphate in ischemia-induced animals, which was prevented by Radix Glycyrrhizae extract treatment. Ischemia/reperfusion increased lipid peroxidation, which was prevented and morphological changes also altered by Radix Glycyrrhizae pharmacopuncture administration. Conclusions: These results indicate that lipid peroxidation plays a critical role in ischemia-induced acute renal failure and Glycyrrhizae Radix pharmacopuncture exerts the protective effect against acute renal failure induced by renal ischemia/reperfusion.
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김형철,이원찬,김종구,홍석진,김경미,조윤식,박성은,김진호,Kim, Hyung-Chul,Lee, Won-Chan,Kim, Jong-Gu,Hong, Sok-Jin,Kim, Kyoung-Mi,Cho, Yoon-Sik,Park, Sung-Eun,Kim, Jin-Ho 해양환경안전학회 2011 해양환경안전학회지 Vol.17 No.4
Based on the consideration of land based pollutant discharges from the basin and seawater quality related carrying capacity and the seawater quality improvement in receiving water bodies of Yeoja Bay where eutrophication and organic pollution are in progress, were evaluated. The permissible inflow loads of BOD, TN and TP by using the geographical features and box modelling method were estimated. As results, it is shown that the reduction rate of discharged BOD and TP loads were 39.3% and 30.8 %, respectively, however, 6.9% was estimated for TN. According to the pollutant loading in each tributary and generated load of the basin, it is given much weight on the land use group, and also was shown in discharged load estimation. This suggests that it is important to control nonpoint source pollutant such as livestock and land use groups as well as point source to contribute the proposition of the water quality improvement plan according to the characteristics of the bay.
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조류성장잠재력 시험에 의한 사량도 연안 Cochlodinium polykrikoides 적조의 제한영양염
김형철,김동명,이대인,박청길,김학균,KIM Hyung Chul,KIM Dong Myung,LEE Dae In,PARK Chung Kil,KIM Hak Gyoon 한국수산과학회 2001 한국수산과학회지 Vol.34 No.5
Algal growth potential (AGP) assay using Cochlodinium polykrikoides was conducted in Saryang Island coast where C. polykrikoides red tide occurred annually from July to October 1998. The effects of macro- and micro-nutrients on the growth of C. polykrikoides were specifically evaluated by the algal assay method. Two different types of growth response of C. polykikoides for the addition of nutrients were clearly obseued. For both before and after C. polykrikoides occurrence, the growth of C. polykikoides was significantly stimulated by the addition of either nitrate or ammonium of $50{\mu]M$ with phosphate of $5{\mu}M$. The addition of a single nutrient had no clear effect on the growth of C. polyhikoides and the addition of trace metals, vitamins, and EDTA etc. did not stimulate the algal growth, also. This result indicates that both N and P potentially limited the growth of C. polyhikoides in this period. However, during a bloom of C. polyhikoides, the growth was unlikely to be stimulated by the addition of both macro- and micro-nutrients. At that time the nutrient concentration of Saryang Island coast was $24.33{\mu}M$ for ammonium, $1.61{\mu}M$ for phosphate, and $0.58{\mu}M$ for nitrate, respectively. The concentrations of nutrients increased, on average, 8.2-fold for ammonium and 4.8-fold for phosphate, decreased 3.3-fold for nitrate compared to both before and after the red tide. This result shows that the growth of C. polykikoides was not limited by the nutrients during the bloom in September. Therefore, our results suggest that the C. polykrikoides red tide may outbreak especially when the water is fertilized due to the increased N and P.
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10 wt%, 20 wt%Li-TiO<sub>2</sub> 복합분말의 합성과 광촉매 활성평가
김형철,한재길,Kim, Hyeong-Chul,Han, Jae-Kil 한국분말야금학회 2016 한국분말재료학회지 (KPMI) Vol.23 No.1
10 wt.% and 20 wt.%$Li-TiO_2$ composite powders are synthesized by a sol-gel method using titanium isopropoxide and $Li_2CO_3$ as precursors. The as-received amorphous 10 wt.%$Li-TiO_2$ composite powders crystallize into the anatase-type crystal structure upon calcination at $450^{\circ}C$, which then changes to the rutile phase at $750^{\circ}C$. The asreceived 20 wt%$Li-TiO_2$ composite powders, on the other hand, crystallize into the anatase-type structure. As the calcination temperature increases, the anatase $TiO_2$ phase gets transformed to the $LiTiO_2$ phase. The peaks for the samples obtained after calcination at $900^{\circ}C$ mainly exhibit the $LiTiO_2$ and $Li_2TiO_3$ phases. For a comparison of the photocatalytic activity, 10 wt.% and 20 wt.% $Li-TiO_2$ composite powders calcined at $450^{\circ}C$, $600^{\circ}C$, and $750^{\circ}C$ are used. The 20 wt.%$Li-TiO_2$ composite powders calcined at $600^{\circ}C$ show excellent efficiency for the removal of methylorange.
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