無機物이 클로렐라 生育에 미치는 影響

金昌漢 건국대학교 1984 學術誌 Vol.28 No.2

To improve the biomass productivity of Chlorella ellipsoidea, the several minerals affecting the biomass productivity during fermentation were studied. The biomass productivity was increased by the addition of potassium nitrate, potassium phosphate (dibasic), magnesium sulfate and ferrous sulfate. The optimal mineral concentration of media was found to be; 50mM potassium nitrate, 40mM potassium phosphate (dibasic), 24 mM magnesium sulfate and 0.05mM ferrous sulfate. The addition of calcium carbonate was slightly effective to promote growth of Chlorella ellipsoidea at the latter term of fermentation, but inhibited growth of the algae at the previous term of fermentation. On the other hand, the addition of 88mM sodium chloride inhibited markedly growth of Chlorella ellipsoidea.

화학구조의 유사성에 의한 抗生物質의 분류 (Ⅱ)

金昌漢 한국산업미생물학회 1976 한국미생물·생명공학회지 Vol.4 No.3

정보처리(情報處理)와 실제(實際)(I)

김창한,Kim, Chang-Han 한국과학기술정보연구원 과학기술정보센터 1963 Journal of Information Science Theory and Practice Vol.1 No.3

가열처리조건이 희석전란액의 유산발효에 미치는 영향

김창한,유익종,이강익 한국축산학회 1995 한국축산학회지 Vol.37 No.3

The optimum heating temperature of diluted liquid whole egg (egg solid was modified to 8%) was determined through investigation of physico-chemical changes of diluted liquid whole egg for successive lactic acid fermentation. The pH of diluted liquid whole egg heated above 75℃ lowered to below 4.5 after fermentation for 15 hours while the pH of the fermented egg heated at 55, 65℃ showed near 5.0. Titratable acidity of the fermented egg showed the same trends of pH. Heat treatment increased the viscosity of heated egg and the higher heating temperature showed the higher viscosity. After fermentation the viscosity of heated egg increased significantly compared with the viscosity of unfermented heated egg and the liquid egg heated at 120℃ showed the highest viscosity. Lactic acid bacteria count of the fermented egg was over 10^8 CFU/㎖ at the temperature higher than 75℃. Lighmess(L value) of the fermented egg decreased in accordance with the seventy of heat treatment while redness(a value) of the fermented egg showed adverse tendency. Yellowness(b value) of the fermented egg showed similar tendency with lightness.

조피볼락 Sebastes schlegeli 치어의 산소소비 , 질소배설율 및 체물질화학적조성에 미치는 이료내 에너지 / 단백질의 영향

김창한,진평 한국수산과학회 1994 추계학술발표회 Vol.- No.-

GF(2ⁿ)위에서의 다항식 인수분해에 관하여

金昌漢 世明大學校 1994 世明論叢 Vol.3 No.-

The recently developed algorithm of Niederreiter for the polynomial factorization over finite fields. We propose an implementation method for the Niederreiter's algorithm over GF(2ⁿ)using field representations.

醱酵食品의 理化學的 및 微生物學的 性質에 關한 硏究

金昌漢 건국대학교 1980 學術誌 Vol.24 No.2

This experiment was carried out to investigate some physical, chemical and microbiological properties of market milks and various fermented foods which were fermented milks from five makers, and cabbage, young radish and cucumber pickles manufactured on our laboratory, and each two kinds of soy sauce, soybean paste and red popper paste made in factory and those made in home. The results obtained were as follows. 1.Total solid of the market milk was lower than of the fermented milks. Contents of protein, fat, reductive sugar, ash and phosphorus of the market milk were more than those of the fermented milks and calcium content showed similar results. 2.The calorie of the market milk (698cal/ml) was lower than the average calorie of the fermented milks (801cal/ml), and higher than those of SK-Sow(651 cal/ml) and S-Towa(486 cal/ml). The protein VS. calorie ratio of the market milk was fairly lower than those of the fermented milk. 3.When the fermented milks were stored at 4℃ for four days, the tactic acid bacteria counts of Yokurts showed on increasing tendency, and those of S-Sow and S-Towa showed a decreasing tendency. The lactic acid bacteria count of S-Towa stored at 4℃ for four days were inferior to the standard level (1.0 × 107/ml) of the fermented milk. The pH of the fermented milks slightly increased by the 3rd day, but the pH of those started decreasing from the fourth of the storage period. 4.When cabbage young radish and cucumber pickles were fermented at 6℃ for nine days, the lactic acid bacteria (acid production bacteria) counts increased until the seventh days, but those of Kimchi began to decrease from the ninth day of the fermenting period. The each Kimchi was not lower than the fermented milks on ml per lactic acid bacteria (acid production bacteria) count. According to fermentation period, the pH of the each Kimchi leaned to acidic side and acid production amount showed a tendency to increase gradually. A young radish pickles among the Kimchi showed the most gentle pH change. 5.The lactic acid bacteria counts of soy sauce and soybean paste which were made in factory were more than those which were made in home. Halotolerant lactic acid bacteria were found only on the soy sauce and soybean paste which were made in factory. On the red pepper paste, the lactic acid bacteria were not detected on the others expect one kind of the red pepper paste which were made in home. The pH of the brewing foods showed a slight difference by foods. The more titrable acidity of the brewing foods containing more lactic acid bacteria was high.

타입 II 최적 정규기저를 갖는 유한체의 새로운 병렬곱셈 연산기

김창한,장상운,임종인,지성연,Kim Chang-Han,Jang Sang-Woon,Lim Jong-In,Ji Sung-Yeon 한국정보보호학회 2006 정보보호학회논문지 Vol.16 No.4

유한체의 H/W 구현에는 정규기저를 사용하는 것이 효과적이며, 특히 최적 정규기저를 갖는 유한체의 H/W구현이 가장 효율적이다. 타입 I 최적 정규기저를 갖는 유한체 GF($2^m$)은 m이 짝수이므로 암호학적으로 응용되지 못하는 단점이 있다. 그러나 타입 II 최적 정규기저를 갖는 유한체의 경우는 NIST에서 제안한 ECDSA의 권장 커브 중 GF($2^{233}$)위에 주어진 것이 있으며, 이 유한체가 타입 II 최적 정규기저를 갖는 등 여러 응용분야에 적용 되는바 효율적인 구현에 관한 연구가 활발하게 진행되고 있다. 본 논문에서는 타입 II 최적 정규기저를 갖는 유한체 GF($2^m$)의 연산을 정규기저로 표현하여 확대체 GF($2^{2m}$)의 원소로 나타내어 연산을 하는 새로운 병렬곱셈 연산기를 제안하였으며, 제안한 연산기는 기존의 가장 효율적인 결과들과 동일한 공간 및 시간 복잡도를 갖는 효율적인 연산기이다. In H/W implementation for the finite field, the use of normal basis has several advantages, especially, the optimal normal basis is the most efficient to H/W implementation in GF($2^m$). In this paper, we propose a new, simpler, parallel multiplier over GF($2^m$) having a type II optimal normal basis, which performs multiplication over GF($2^m$) in the extension field GF($2^{2m}$). The time and area complexity of the proposed multiplier is same as the best of known type II optimal normal basis parallel multiplier.

Lactobacillus casei YIT9018로부터 분리, 정제한 Whole Peptidoglycan의 In Vitro 항종양활성

金昌漢,李明燮,高時煥,朴相瑨,朴圭炫,白永振 건국대학교 생명과학연구원 1995 생명과학지 Vol.2 No.1995

The Effects of Calcium-Phosphate Coated Xenogenic Bone and Type I Collagen for Bone Regeneration on the Calvarial Defects in Rabbits

김창한,박진우,이재목,서조영,Kim, Chang-Han,Park, Jin-Woo,Lee, Jae-Mok,Suh, Jo-Young The Korean Academy of Periodontoloy 2004 Journal of Periodontal & Implant Science Vol.34 No.1

골재생을 위해 사용되는 골이식재로 자가골, 동종골, 이종골 등이 있다. 자가골은 가장 예지성이 높은 골이식재이지만, 부가적인 수술, 환자의 동통과 불편, 채취하는 양의 제한, 비용의 증가 등의 단점이 있다. 따라서 많은 연구자들은 오랫동안 자가골을 대체할 골이식재 개발에 힘써왔고, 다양한 연구가 있었다. 소로부터 유래한 이종골은 천연 다공성의 골 무기질로서, 인간의 골의 구조와 유사하면서, 골 전도성이 있고, 생체 적합성이 뛰어나다고 보고되었다. 이에 최근에 개발된 Ca-P 박막이 이종골과 조작성을 용이하게 하기 위해 부가적으로 type I collagen을 혼합한 골이식재를 토끼 두개골 결손부에 매식하여 골형성 능력 및 주변 조직의 반응을 보고자 하였다. 총 16마리의 New Zealand white rabbits를 사용하였고, 두개골에 4부위의 결손부를 형성한 후, 다음과 같이 적용하였다. 이식재를 넣지 않은 군을 음성대조군으로, 자가골 분말을 이식한 군을 양성대조군으로, Ca-P 박막 탈단백 우골 분말을 이식한 군을 실험1군으로, Ca-P 박막 탈단백 우골 분말과 type I collagen을 같은 부피로 혼합하여 이식한 군을 실험2군으로 하였다. 1, 2, 4, 8주째 4마리씩 희생하여, H-E 염색과 Masson's trichrome 염색을 시행한 후, 광학현미경을 사용하여 조직학적으로 관찰하였다. 토끼 두개골 결손부에 이식한 Ca-P 박막 탈단백 우골은 골성회복초기에 골결손부 변연에서 골전도성을 보였지만, 완전한 골성회복을 이루지 못하였고, 신생골과 직접적인 유합을 보이지 않았다. 또, collagen의 부가적인 사용은 조작성은 가장 우수했으나, 조직소견상 신생골의 형성을 보이지는 않았다. 반면 자가골을 이식한 부위는 신생골 형성양과 밀도에 있어서 가장 우수한 결과를 보였다. The purpose of this present study evaluated the osseous response around Ca-P coated xenogenic bone and compared osteogenic potential of Ca-P coated xenogenic bone to that of combination with type I collagen derived from bovine tendon as a biocompatible binder to prevent migration of bone particle on the repair of calvarial defects in rabbits. To study the effects of Ca-P coated xenogenic bone and collagen on bone healing, four 5-mm-diameter skull defect were made in calvaria with trephine filled with an autogenous bone chip or Ca-P coated xenogenic bone or Ca-P coated xenogenic bone and type I collagen (1:1 mixture by volume) or left empty. The defects were evaluated histologically at 1, 2, 4 and 8 weeks following implantation. Ca-P coated xenogenic bone at the calvarial defects of rabbits showed osteoconductivity at the margin of defect in the early stage of bony healing, but no direct contact with new bone was observed. With time passed by, it was resorbed slowly and showed consistent inflammatory reaction. An additional use of type I collagen derived from bovine tendon improved clinical handling, but no new bone formation was observed histologically. Above all, autogenous bone graft showed most prominent healing in quantity and density of new bone formation. According to this study, the use of Ca-P coated xenogenic bone alone and combination with type I collagen did not showed effective healing in quantity and density of new bone formation.