아시아 소아 신장이식 현황

김지홍,최용,김병길,Kim Ji-Hong,Choi Yong,Kim Pyung-Kil 대한소아신장학회 2002 Childhood kidney diseases Vol.6 No.2

Purpose : Renal transplantation which allows children normal growth and development and a return to normal life. is now proven to be the best modality for children with ESRD Up to Recently, the number of renal transplantations in Asia has rapidly increased and the outcome has also improved. This investigation was planned to estimate the current status of pediatric renal transplantation in Asia and to find the keys for better improvement of outcome in pediatric renal allograft in Asian countries. Material and methods : The participating countries and institutions for this investigation were China, Hong Kong, India, Indonesia, Japan, Malaysia, Pakistan, Philippines, Singapore, Thailand, Korea, KSPN (Korean Society of Pediatric Nephrology), KONOS (Korean Network for Organ Sharing). Results : Many countries in Asia still do not have a well organized nation wide renal transplantation registration system independently in the pediatric field. So it's very difficult to evaluate the real state of pediatric transplantation among Asian countries. According to the estimation with fragmented data from each countries, in the front running countries of pediatric renal transplantation in Asia, about 40 or more transplants were performed in each country per year and the five year actuarial renal allograft survival was around 80% which is similar to that of western countries. But there were large gaps among the behind groups. Conclusion : Vigorous attempts to perform renal transplantation for children especially younger than 5 years old would be encouraged as well as organ donation from brain dead donor and non heart beating cadaveric donor also should be activated to cope effectively with the shortage of living donor supply. Large number of recent reports shows the favorable outcome of pre-emptive renal transplantation, we should make more efforts toward pre-emptive renal transplantation. First of all, in order to improve the outcome and to narrow the gap between Asian countries in pediatric renal transplantation, effective and continuous efforts to establish nationwide pediatric renal transplantation registration program as well as official, nation-to-nation data sharing program should be needed.

분산시스템에서의 속성인증서를 이용한 접근통제방안

김지홍,박종화,황태현,Kim, Ji-Hong,Park, Chong-Hwa,Hwang, Tae-Hyun 한국정보기술전략혁신학회 2003 情報學硏究 Vol.6 No.1

With the development of Information Communication Technique, electronic commerce is widely used in internet using public key certificates. And the study for access control in database system is also progressed actively. In this paper, we analyze access control mechanism using attribute certificated and we propose new access mechanism in distributed system using attribute certificates.

한국교육학술정보원(KERIS) 상호대차시스템을 활용한 문헌입수의 평균 소요시간과 성공률(제공율)에 대한 연구

김지홍,Kim, Ji-Hong 한국도서관협회 2002 圖協會報 Vol.43 No.1

비정규직 사서의 취업 현황과 해결방안

김지홍,Kim, Ji-Hong 한국도서관협회 2004 圖協會報 Vol.45 No.5

소아 신증후군에서 Cyclosporine A에 의한 만성 조직학적 신독성의 발현빈도에 대한 연구

김지홍,정현주,최인준,김병길,Kim Ji-Hong,Jeong Hyun-Ju,Choi In-Jun,Kim Pyung-Kil 대한소아신장학회 1999 Childhood kidney diseases Vol.3 No.2

Purpose : Long-term use of Cyclosporine(CsA) reduce renal blood flow by afferent arteriolar vasoconstriction and lead to chronic pathologic changes of CsA nephrotoxicity - 1) interstitial nephritis(IN); tubular atrophy (TA) and/or interstitial fibrosis(IF),2) arteriolopathy(AP). The Object of this study is to estimate the incidence of chronic pathologic CsA nephrotoxicity by duration of treatment and type of renal disease, relationship between histologic and clinical nephrotoxicity, and optimal duration of CsA therapy. Methods : 102 children with steroid resistant or dependent nephrotic syndrome confirmed by renal biopsy and treated with CsA from 1986 to 1997 were enrolled in this study(58 MCNS, 10 FSGS, 10 MGN, 15 $Henoch-Sch\"{o}nlein$ purpura nephritis with nephrotic syndrome (HSPN) and 9 IgA nephropathy with nephrotic syndrome(IgAN)). CsA was administered for 1yr, 1.5yr, 2yr in 24, 12, 22 MCNS patients and 2, 2, 6 FSGS patients respectively, 1yr, 2yr in MGN and 1yr in HSPN and IgAN. Sequential biopsies were done in all 102 patients after CsA treatment for evaluation of pathologic nephrotoxicity. Results : Complete remission rate was 92.2% (100% in MCNS and MGN, 80% in FSGS, 86.6% in HSPN and 55.5% in IgAN). Incidence of relapse during 6months after CsA treatment was significantly decreased compaed with relapsing spisodes during 6months before CsA treatment in MCNS(P<0.0001) and FSGS(P<0.0001). According to pathologic changes, 71 patients(69.6%) showed no pathological change, 24 patients(23.5%) showed IN and 7 patients(6.8%) showed AP. IN was 16.6%, 33.3%, 27.2% in 1, 1.5, 2 year of CsA treatment group in MCNS. AP was 0%, 16.6%, 9% in 1, 1.5, 2 year of CsA treatment group in MCNS. 14 out of 58 MCNS(24.1%) showed IN and 4 out of 58 MCNS(6.8%) showed AP. Incidence of pathologic change was significantly lower in CsA therapy of <1yr than >1yr(P=0.03). There were no significant difference of incidence of pathologic change in original renal disease, age and sex. Conclusion : Duration of CsA treatment was significant risk factor for nephrotoxicity and optimal duration seemed to be 1 year. Pathologic change due to nephrotoxicity did not correlate with deterioration of renal function and only detectable by renal biopsy.

지리공간 유통망 보안 방안에 관한 연구

김지홍,임기욱,Kim, Ji-Hong,Lim, Gi-Uk 한국공간정보학회 2001 개방형지리정보시스템학회 논문지 = Journal of the Korea Open Geogr Vol.3 No.2

The GIS Network consists of the Clearinghouse Network Gateway and Clearinghouse Node and Geo-spatial Data Server. Recently with the development of Information and Network technologies, GIS Network should be needed to be more secure than ever. In this paper, we proposed the effective access control method for the distributed GIS network. PKI (Public Key Infrastructure) Technologies are used for access control and security for transmission on Geo-spatial data

알포트증후군 환자에서 안지오텐신전환효소 유전자 다형성의 의의

김지홍,이재승,김병길,Kim Ji-Hong,Lee Jae-Seung,Kim Pyung-Kil 대한소아신장학회 2004 Childhood kidney diseases Vol.8 No.1

Purpose : Alport syndrome is clinically characterized by hereditary progressive nephritis causing ESRD with irregular thickening of the GBM and sensory neural hearing loss. The mutations of type IV collagen gene(COL4A5) located on the long arm of X chromosome is considered responsible for most of the structural abnormalities in the GBM of Alport patients. Since no definite clinical prognostic predictor has been reported in the disease yet, we designed this study to evaluate the significance of genetic polymorphism of the angiotensin converting enzyme in children with Alport syndrome as a prognostic factor for disease progression. Methods : ACE I/D genotype were examined by PCR amplification of the genomic DNA in 12 patients with Alport syndrome and 12 of their family members. Alport patients were divided into two groups; the conservative group, those who had preserved renal function for more than 10 years of age, the early CRF group, those who had progressed to CRF within 10 years of age. Results : The mean age of onset was $3.45{\pm}2.4$ years in the conservative group, $4.4{\pm}1.2$ years in the early CRF group. Sex ratios were 5:3 and 2:1 in each group. Among 12 cases of patients, 4 cases were in early CRF group and their mean duration of onset to CRF was 4.5 yews(8.9 years of age). Eight patients(67%) were in the conservative group and they had normal renal function for more than 10 years of age(mean duration of renal preservation was 10.6 years). The incidence of II type ACE gene were in 25.0%(3 cases), ID type in 41.7%(5 cases), DD type in 33.3%(4 cases). There was no significant difference between Alport patient and normal control(II type 44.3%, ID type 40.9%, DD type 14.8%). The incidence of DD type of early CRF group were higher than that of the conservative group(75% vs 12.5%)(p<0.05). There was no difference in ACE gene polymorphism between normal Alport family members and control group. Conclusion : Even though there was no significant difference of ACE polymorphism between Alport patients and the normal control group, the incidence of DD type is significantly increased in early CRF group which means DD type of ACE polymorphism has a possibility of being a predictor for early progression to CRF in Alport patients.

체액의 수분 및 나트륨 균형

김지홍,Kim, Ji-Hong 대한소아신장학회 2010 Childhood kidney diseases Vol.14 No.2

The maintenance of the osmolality of body fluids within a very narrow physiologic range is possible by water balance mechanisms that control the intake and excretion of water. Main factors of this process are the thirst and antidiuretic hormon arginine vasopressin (AVP), secretion regulated by osmoreceptors in the hypothalamus. Body water is the primary determinant of the osmolality of the extracellular fluid (ECF), disorders of body water homeostasis can be divided into hypo-osmolar disorders, in which there is an excess of body water relative to body solute, and hyperosmolar disorders, in which there is a deficiency of body water relative to body solute. The sodium is the predominant cation in ECF and the volume of ECF is directly proportional to the content of sodium in the body. Disorders of sodium balance, therefore, may be viewed as disorders of ECF volume. This reviews addresses the regulatory mechanisms underlying water and sodium metabolism, the two major determinants of body fluid homeostasis for a good understanding of the pathophysiology and proper management of disorders with disruption of water and sodium balance.

통계적 특성에 의한 객체 영상 검출방안

김지홍,Kim, Ji-hong 한국정보통신학회 2018 한국정보통신학회논문지 Vol.22 No.7

As the study of the object feature detection from image, we explain methods to identify the species of the tree in forest using the picture taken from dron. Generally there are three kinds of methods, which are GLCM (Gray Level Co-occurrence Matrix) and Gabor filters, in order to extract the object features. We proposed the object extraction method using the statistical properties of trees in this research because of the similarity of the leaves. After we extract the sample images from the original images, we detect the objects using cross correlation techniques between the original image and sample images. Through this experiment, we realized the mean value and standard deviation of the sample images is very important factor to identify the object. The analysis of the color component of the RGB model and HSV model is also used to identify the object.

터치 터미널의 개요

김지홍,Kim, Ji-Hong 한국정보통신집흥협회 1991 정보화사회 Vol.48 No.-