쥐(rats)의 full-thickness skin grafts에 대한 hyperbaric oxygen과 α-tocopherol의 효과

김종수,김충희,김곤섭,하대식,박성근,김양미,Kim, Jong-shu,Kim, Chung-hul,Kim, Gon-sup,Hah, Dae-sik,Park, Sun-gun,Kim, Yang-mi 대한수의학회 2000 大韓獸醫學會誌 Vol.40 No.3

To document that effects of hyperbaric oxygen(HBO) and ${\alpha}-tocopherol$ on full-thickness skin grafts in rat, we performed full-thickness skin grafts bilaterally on each rats. The HBO-treated rats were received HBO twice daily for 90 minutes at 2 ATA. Surgical control rats were not treated with HBO. ${\alpha}-tocopherol$ treated rats were received the agent via oral gastric tube daily for 3 days preoperative and a fourth dose 1 to 2 hours postoperative. HBO plus ${\alpha}-tocopherol$ treated rats were received HBO and ${\alpha}-tocopherol$ as mentioned above. Biopsy specimens were taken from each rat at the time of grafting and on days 2, 4, 7, 10, 14, 21, and 28, then were processed for tissue-concentration of total glutathione(GSHt), oxidized/reduced glutathione level, and thiobarbituric acid-reactive substance(TBARS) levels. The percentage of viable graft on day 10 ranged from 67 to 93%, and was not significantly different among the each other groups. The percentage of viable graft were, however, higher in HBO plus ${\alpha}-tocopherol$ treated rats(78.6%) than in HBO alone treated rats(59.1%), ${\alpha}-tocopherol$ alone treated rats(66.7%) and surgical control rats(58.2%). TBARS concentration had a significant increase from preoperative concentration at day 2, and peak concentration at day 4(p<0.01). Concentration then decreased to preoperative concentration at day 28. GSHt concentration of free skin graft had a similar patteren of change in four groups and decreased significantly from preoperative concentration at day 2, returning to preoperative concentration by day 7(surgical control, HBO-treated, and ${\alpha}-tocopherol-treated$, alone) and 28(HBO plus ${\alpha}-tocopherol-treated$). Percentage of the concentration of reduced glutathione decreased in surgical control, HBO-treated and, ${\alpha}-tocopherol-treated$(p<0.05), and HBO plus ${\alpha}-tocopherol-treared$(p<0.01) on day 7 after surgery, whereas the concentration of oxidized increased significantly in HBO-treated(p<0.05), ${\alpha}-tocopherol-treated$(p<0.05), and HBO plus ${\alpha}-tocopherol-treated$(p<0.01).

내측광근 강화운동을 이용한 슬개-대퇴 동통 증후군 치험 2례

김종수,김진수,김세준,정승현,김효섭,윤문식,조태영,Kim, Jong-Su,Kim, Jin-Soo,Kim, Se-Jun,Jeong, Seong-Hyun,Kim, Hyo-Sub,Yoon, Moon-Sik,Cho, Tae-Young 척추신경추나의학회 2013 척추신경추나의학회지 Vol.8 No.1

슬개-대퇴 통증 증후군 환자 2례에 내측광근 강화 운동을 이용하여 치료한 결과, Knee X-ray(Skyline view) 상의 일치각 및 NRS, WOMAC Index의 호전을 확인하였다. 이에 저자는 본 증례를 보고하는 바이다. Objectives: The purpose of this case report is to investigate the effect of exercise for vastus medialis to knee pain patients with patello-femoral pain syndrome. Methods: Two patients with patello-femoral pain syndrome were treated by exercise for vastus medialis. To measure the outcome of the patients' improvement, we observed the X-ray of both knee sky-line view, Numerical Rating Scale(NRS), and Western Ontario and McMaster Universities(WOMAC) index. Results: After being treated by exercise for vastus medialis, the patients' X-ray of both knee sky-line view, Numerical Rating Scale(NRS), and Western Ontario and McMaster Universities(WOMAC) index were significantly improved. Conclusions: These results suggest that exercise for vastus medialis is effective treatment to patients with patello-femoral pain syndrome.

Diazinon이 계배(鷄胚)의 기형 유발에 미치는 효과 I. 계배(鷄胚) 형태와 콜린성 봉쇄약물에 미치는 효과

김종수,김곤섭,김양미,최원영,손성기,허정호,이주홍,Kim, Jong-shu,Kim, Gon-sup,Kim, Yang-mi,Choi, Wong-young,Son, Sung-gi,Heo, Jung-ho,Lee, Ju-hong 대한수의학회 1994 大韓獸醫學會誌 Vol.34 No.1

Teratogenic effects of diazinon were assessed on morphology of chick embryos cholinergic blocking agents. Diazinon at doses ranging from 25 to $2000{\mu}g/egg$, was injected on Day 3 of incubation. $TD_{50S}$, were different for the various teratogenic sings such as wry neck, micromelia, abnormal feathering, abnormal beak and curled claws. The threshold dose for wry neck was higher than the threshold dose for other signs; $40{\mu}g/egg$ produced substantial micromelia, abnormal feathering, abnormal beak and curled claws, but gave no sings of wry neck. In contrast to the teratogenic doses, the $LD_{50}$ of diazinon was very high(above $2000{\mu}g/egg$). One of the characteristics of diazinon-induced teratogenesis was reduction of body weight(78.8%) and body length(73.8%). Maximal teratogenic effects, scored as sings of retarded growth, wry neck, micromelia, abnormal feathering, abnormal beak, and curled claws, were produced when the insectcide was administered on the third or fourth day. The threshold dose for type II teratogenic sings including wry neck and short neck was higher than for type I including micromelia and abnormal feathering. Morphorlogical studies, using atropine and gallamine, suggested that nicotinc but not muscarinic receptors may be involved in the mechanism of diazinon-induced type II malformations.

미국 무역센터의 붕괴 메커니즘

김종수,Kim, Jong-Su 한국건축구조기술사회 2001 건축구조 Vol.8 No.4

초고층 주거용 건물의 구조시스템 분석 및 설계

김종수,Kim, Jong-Su 한국건축구조기술사회 2004 건축구조 Vol.11 No.1

Streptomyces coelicolor의 Protoplast Fusion 방법개발

김종수,이세영,Kim, Jong-Su,Lee, Se-Yong 한국미생물학회 1984 미생물학회지 Vol.22 No.1

Streptomyces속 균주개발의 수단으로서 이용할 목적으로 원형질체 융합방법의 확립을 시도하였다. 특히 융합빈도를 높이고 실험을 간편화하는데 역점을 두었다. 원형질체의 형성 및 재생빈도는 균의 배양시간에 따라 변하였는데 대수기에서 수확한 균체로부터 가장 높은 빈도의 수율을 얻었다. 원형질체의 형성은 다른 용균효소를 사용하지 않고 Lysozyme 단독처리 만으로도 충분히 가능하였고 원형질체의 세포막 재생은 Monolay법 보다는 Overlay법이 훨씬 좋은 결과를 주었다. Monolay법은 1.8%, Overly법은 14%의 재생빈도를 나타냈다. 본 실험에서 PEG1000 (50% W/V)를 사용한 원형질체 융합방법으로 얻은 S. coelicolor의 재조합체의 빈도는 $1.8 {\times} 10^{-2}$이었다. Attempts were made to optimise protoplast formation and regeneration methods to improve the protoplast fusion frequencies of Streptomyces coelicolor. The yields of protoplast formation and regeneration were varied with different growth phase of the culture. Maximum yields were obtained when cells were taken from the late logarithmic phase. Protoplast formation reached almost its maximum with lysozyme treatment at a concentration of 2mg/ml without any other lytic enzyme. A high frequency of protoplast regeneration was accomplished by overlay method: the method gave 14% recovery of regenerated protoplast versus 1.8% recovery for monolay method. A recombinant frequency of 1.8X10^-2 was obtained by protoplast fusion using PEG 1000(50% w/v).

대형 슬래브 건물의 온도하중 및 조인트 해석

김종수,Kim, Jong-Su 한국건축구조기술사회 2002 건축구조 Vol.9 No.2

자동차 공조장치용 증발기의 전열 성능 예측

김종수,강정길,Kim, J.S.,Kang, J.K. 대한설비공학회 1991 설비공학 논문집 Vol.3 No.4

Recently, automotive air conditioning system manufacturers have been made a great efforts on the system compactness and high efficiency. This growing interest comes improvements in evaporator thermal performance, one of the most important factors affecting the performance of air conditioning system. In order to improve design of compact type evaporator, this study executes performs to develop a computer program for evaporator thermal performance prediction of automotive air conditioning system. The brief summaries of this study are as follows: 1) To predict the overall thermal performance of serpentine type evaporator, the new simulating method is developed. 2) The calculations are performed as functions of oil mass concentration and refrigerant two-phase distribution at inlet manifold of evaporator. 3) The validity of this simulating program is confirmed by comparing the predicted thermal performance results to experimental results of practical available evaporator. 4) Based on these results, suggestions are made to improve the thermal performance of evaporator.

한국(韓國) 동해대륙단(東海大陸端) 해저지질(海底地質)

김종수,Kim, Chong Su 대한자원환경지질학회 1982 자원환경지질 Vol.15 No.2

In the last ten years, marine geological and geophysical survey and research were conducted by Japanese, Russian and American scientists in the East Sea of Korea (Japan Sea). Many research results were published. However, regional research of the geology of the continental margin of the Korean Peninsula was not conducted. This study has made on attempt to classify submarine strata and stratigraphic boundaries. The study has revealed characters of submarine geology and structure. Isopach maps of each identified stratigraphic unit have been constructed as the results of this study. The study was conducted on the basis of analyses of marine seismic surveys carried out in the continental margin of the East Sea between Kangneung and Pohang. Three depositional basins were identified in the study area and they were named as, Mukho Basin, Hupo Basin and Pohang Basin. The Mukho Basin is developed in continental slope and shelf in the area between Kangneung and Samcheog. Quaternary and Pliocene sediments attain a maximum thickness of 900 m. Basement rocks are interpreted as granite and gneiss. They are correlated with granite-gneiss of the Taebaecksan Series of Pre-cambrian age and the Daebo granite of Jurassic age. The Hupo Basin is developed in the continental shelf between Uljin and Youngdeok. Quaternary and Pliocene sediments attain a maximum thickness of 600 m. Basement rocks were interpreted as granite and gneiss and they are correlated with metamorphic rocks of Pre-cambrian age and the Daebo granites, comprising the Ryongnam Massif. The Pohang Basin is developed in the area between Pohang and Gangu. This basin contains Miocene and older sediments. Basement rocks are not shown. Many faults are developed within the continental shelf and slope. These faults strike parallel with the coast line. A north-south direction is predominant in the southern study area. However, in the northern study area the faults strike north, and north-west. The faults are parallel to each other and are step faults down-thrown to the east or west, forming horst and graben structures which develop into sedimentary basins. Such faults caused the development of submarine banks along the boundary between the continental shelf and slope. This bank has acted as a barrier for deposition in the Hupo Basin. Paleozoic sedimentary rocks distributed widely in the adjacent land area are absent in the Mukho Basin. This suggests that the area of the basin was situated above the sea level until the Pliocene time. The study area contains Pliocene sediments in general. These sediments overlie the basement complex composed of metamorphic rocks, granites, Cretaceous (Kyongsang System) sedimentary rocks and Miocene sedimentary rocks. These facts lead to a conclusion that the continental shelf and slope of the study area were developed as a result of displacements along faults oriented parallel to the present coast line in the post Miocene time.

반복하중을 받는 Dobby Hook의 설계에 관한 실험적 연구

김종수,이규정,이태세,Kim, Jong-Su,Lee, Gyu-Jeong,Lee, Tae-Se 한국기계연구원 1990 기계연구원소보 Vol.20 No.-

Hook of Dobby is a important part of shedding device, which must be endured the repeated loading force. In this paper, experiment on various mechanical characteristics; measurement of loading force were carried out, and compared the experimental values with results of Finite Element Method.