척수 손상 환자의 신경인성 방광에서 방광확대성형술의 장기 성적

김윤범,박원희,심홍방 大韓泌尿器科學會 2003 Korean Journal of Urology Vol.44 No.6

3-MCA 誘發 上皮腫에 對한 香貝養榮湯과 貝母單味劑가 免疫反應에 미치는 影響

金倫範,蔡炳允 대한한방종양학회 1997 대한한방종양학회지 Vol.3 No.1

Hyangpaeyangyeongtang, which was first Prescribed in the book of Euijonggumgam (醫宗金鑑), has been widely applied to the treatment of scrofula and carbuncle in the neck and tumor as well in the oriental medicine. The Fritillariae roylei bulbus was also used as an anti-tumor medicine. In order to investigate the effect of Hyangpaeyangyeongtang and Fritillariae roylei bulbus extracts on the immune responses to the epithelioma induced by 3-methylcholanthrene and prostaglandin-F_2α in mice, the change of epithelioma size was observed and delayed type hypersensitivity, hemagglutinin titer, hemolysin titer, rosette forming cells, natural killer cell activity, lymphocyte transformation, productivity of interleukin-2 and phagocytic activity were also measured. The results were as follows; 1. The epithelioma size was decreased with statistical significance in the Hyangpaeyangyeongtang group at the 14th day, as compared with the control group, 2. Delayed type hypersensitivity was not shown any decrease in the Hyangpaeyangyeongtang group and the Fritillariae roylei bulbus group, as compared with the control group, 3. Hemagglutinin titer was increased with statistical significance in the Hyangpaeyangyeongtang group, but not in the Fritillariae roylei bulbus group as compared with the control group. 4. Hemolysin titer was increased with statistical significance in the Hyangpaeyangyeongtang group, but not in the Fritillariae roylei bulbus group as compared with the control group. 5. Rosette forming cells were not increased in the Hyangpaeyangyeong tang group, but increased with statistical significance in the Fritillariae roylei bulbus group as compared with the control group. 6. Natural killer cell activity at the ratio 100:1 of effector cells to target cells was increased with statistical significance in the Hyangpaeyangyeongtang group and the Fritillariae roylei bulbus group respectively, and the natural killer cell avtivity at the ratio of 50:1 and 10:1 of effector cells to target cells Hyangpaeyangyeongtang group was increased with statistical significance as compared with the control group. 7. Lymphocyte transformation was increased in the Hyangpaeyangyeong tang group and the Fritillariae roylei bulbus group respectively, as compared with the control group. 8. Productivity of interleukin-2 was increased in the Hyangpaeyangyeong tang group and the Fritillariae roylei bulbus group respectively, as compared with the control group. 9. Phagocytic activity was not shown any decrease in 7he Hyangpaeyangyeongtang group and the

면분자(面粉刺)에 대(對)한 임상적(臨床的) 고찰(考察)

김윤범,김중호,채병윤,Kim, Yoon-Bum,Kim, Joong-Ho,Chae, Byung-Yoon 대한한의학회 1994 대한한의학회지 Vol.15 No.2

The clinical study was done in 50 patients with acne who had been treated with acupuncture and herb-medicine. The results were as follows. There were 9 males and 41 females in sex. The peak age at onset was 21 - 30 years old(28 cases. 56%). The most commen chief complaint was itching(70%). As for digestion. 24 cases(48%) is poor and defecation disorder appeared 25cases 50%). difficult menstruation 20 cases (48.78%). Bohyulansintang(補血安神湯) was most use in treatments as 26.38%.As for treatment period. 25 cases(50%) were treated from 1 week to 3 weeks.

척수 손상 환자의 신경인성 방광에서 방광확대성형술의 장기 성적

김윤범,박원희,심홍방 대한비뇨의학회 2003 Investigative and Clinical Urology Vol.44 No.6

綠風에 對한 臨床的 考察

김윤범,채병윤,Kim, Yoon-Bum,Chae, Byung-Yoon 대한한방안이비인후피부과학회 1995 한방안이비인후피부과학회지 Vol.8 No.1

We observed and studied about 14 cases of clinically glaucoma patients. Glaucoma is called NOK PUNG(綠風) in oriental medicine. Generally glaucoma patients, visiting oriental hospital, have a lower intraocular pressure than that of patients, visting western hospital. The weaksight and asthenopia were improved by acupunctural and Medicinal herbal therapy.

피부요관창냄술 후 발생한 원발성 요관 편평세포암종

김윤범,이광염,박용설,이정기,정태영,곽철,심홍방 대한비뇨의학회 2003 Investigative and Clinical Urology Vol.44 No.4

3-MCA 유발(誘發) 상피종(上皮腫)에 대(對)한 향패양영탕(香貝養榮湯)과 패모단미제(貝母單味劑)가 면역반응(免疫反應)에 미치는 영향(影響)

김윤범,채병윤,Kim, Yun-Beom,Chae, Byeong-Yun 대한암한의학회 1997 大韓癌韓醫學會誌 Vol.3 No.1

Hyangpaeyangyeongtang, which was first prescribed in the book of Euijonggumgam (醫宗金鑑), has been widely applied to the treatment of scrofula and carbuncle in the neck and tumor as well in the oriental medicine. The Fritillariae roylei bulbus was also used as an anti-tumor medicine. In order to investigate the effect of Hyangpaeyangyeongtang and Fritillariae roylei bulbus extracts on the immune responses to the epithelioma induced by 3-methylcholanthrene and prostaglandin-$F_2{\alpha}$ in mice, the change of epithelioma size was observed and delayed type hypersensitivity, hemagglutinin titer, hemolysin titer, rosette forming cells, natural killer cell activity, lymphocyte transformation, productivity of interleukin-2 and phagocytic activity were also measured. The results were as follows; 1. The epithelioma size was decreased with statistical significance in the Hyangpaeyangyeongtang group at the 14th day, as compared with the control group. 2. Delayed type hypersensitivity was not shown any decrease in the Hyangpaeyangyeongtang group and the Fritillariae roylei bulbus group, as compared with the control group. 3. Hemagglutinin titer was increased with statistical significance in the Hyangpaeyangyeongtang group, but not in the Fritillariae roylei bulbus group as compared with the control group. 4. Hemolysin titer was increased with statistical significance in the Hyangpaeyangyeongtang group, but not in the Fritillariae roylei bulbus group as compared with the control group. 5. Rosette forming cells were not increased in the Hyangpaeyangyeong tang group, but increased with statistical significance in the Fritillariae roylei bulbus group as compared with the control group. 6. Natural killer cell activity at the ratio 100:1 of effector cells to target cells was increased with statistical significance in the Hyangpaeyayeongngtang group and the Fritillariae roylei bulbus group respectively, and the natural killer cell activity at the ratio of 50:1 and 10:1 of effector cells to target cells Hyangpaeyangyeongtang group was increased with statistical significance as compared with the control group. 7. Lymphocyte transformation was increased in the Hyangpaeyangyeong tang group and the Fritillariae roylei bulbus group respectively, as compared with the control group. 8. Productivity of interleukin-2 was increased in the Hyangpaeyangyecing tang group and the Fritillariae roylei bulbus group respectively, as compared with the control group. 9. Phagocytic activity was not shown any decrease in the Hyangpaeyangyeongtang group and the Fritillariae roylei bulbus group, as compared with the control group.

삼출성 중이염에 대한 임상적 고찰

김윤범,채병윤,Kim, Yun-Beom,Chae, Byeong-Yun 대한한방안이비인후피부과학회 1992 한방안이비인후피부과학회지 Vol.5 No.1

We analyzed clinical study in 47 patients, who had visited to the Dept. of Otolaryngology, Hospital of Oriental Medicine, Kyung Hee University to treat Otitis media with effesion from March, 1991 to February, 1992. The clinical etiology of O.M.E. was tubal occlusion, acute otitis, and allergy. The clinical symptoms were hearing loss, tinnitus, sneezing, coughing, Chun-I(纏耳), and BEE-Yeon(鼻淵) in the Oriental Medicine. The results were as follows. 1. There were 26 males ($55\%$) and 21 females ($45\%$) in sex. 2. The peak age at onset was 1-4 years old (11Cases). 3. Bilateral effusion was in $62\%$, and unilateral in $38\%$. 4. The etioloigic factors were upper respiratory infection 16 cases, Allergic rhinitis 13 cases, Sinusitis 8 cases, etc. 5. The most common chief complaint was hearing loss ($30\%$). 6. There was no significant difference between blood types in O.M.E., ( A type $30\%,\;B\;type\;25\%,\;AB\;type\;13\%,\;0\;type\;13\%$, Unknown recorded $9\%$ ). 7. $21\%$ patients prefered warm and the others cold 8. As for digestion, good was in 31 cases ($81\%$), and poor 9 cases ($19\%$). 9. Man-Hyung-Ja-San Extract was most used in treatments as $38\%$, O-Ryung-San $35\%$ in descending order. 10. As for treatment period, 14 cases were treated over 12 weeks, 9 cases below 1 week

전통 한방처방을 이용한 기초 한방화장품에 대한 임상적 연구

김윤범,김호철,Kim, Yoon-Bum,Kim, Ho-Cheol 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.1

During a clinical test with Korean herbal cosmetics, significant data and related results are summarized as following: 1. The questionnaire resulted the subjects who used Korean herbal cosmetics showed significant subjective improvement. 2. $11{\%}$ of the subjects who used Korean herbal skin lotion replied "very good" , $60{\%}$ "good" , and $29{\%}$ "so so". 3. In the questionnaire about how often the subjects who used Korean herbal skin lotion experienced skin irritation, $91{\%}$ of the subjects replied they didn't experience any skin irritation 4. The subjects who used oily & combinational cosmetics showed more significant result than the placebo group in the questionnaire about how they feel when using emulsion. 5. In the questionnaire about how they feel when using emulsion. $11{\%}$ of all the subjects replied "very good" , 60{\%}$ "good" , and $29{\%}$ "so so". 6. In the questionnaire about how they feel when using essence $18{\%}$ of all the subjects replied "very good" , $56{\%}$ "good" , and $27{\%}$ "so so". 7. In the questionnaire about how often the subjects who used skin lotion experienced skin irritation, $100{\%}$ of the subjects replied there was no skin irritation. 8. the subjects who used Korean herbal cosmetics showed significant result in the questionnaire about how much moisture they feel when using cream. 9. The subjects who used neutral & dry cosmetics showed more significant result than the placebo group in the questionnaire about if the cosmetics spread well when using emulsion. 10. The subjects who used oily & combinational cosmetics showed more significant result than the placebo group in the questionnaire about how much moisture they feel when using cosmetics. 11. In the questionnaire about how they feel when using cream $13{\%}$ of all the subjects replied "very good", $49{\%}$ "good", and $2{\%}$ "so so". 12. In the questionnaire about how often the subjects who used cream lotion experienced skin irritation, $96{\%}$ of the subjects replied there was no skin irritation. 13. In the measurement of coreometer, the subjects who used oily & combinational cosmetics showed significant result(measurement area : indang). Especially in the area of sungjang there is significant difference between the subjects group and placebo group. 14. In the measurement of skin-ph-meter, there was no significant change in all group. 15. in the measurement of melanin-erythema index meter, the subjects who used cosmetics which doesn't contain Korean herbs showed significant change and made significant difference in comparison to the subjects who used Korean herbal cosmetics.

외관과(外官科) 외래환자의 통계적 고찰

김윤범,Kim, Yoon-bum 대한한방안이비인후피부과학회 2000 한방안이비인후피부과학회지 Vol.13 No.1

We analyzed statistics study in 1695 patients, who had visited to the Dept. of surgery, ophthalmology & otolaryngology Hospital of Downtown Orirental Medicine Kyung Hee University from March, 1996 to July, 1998. The results were as follows. 1. Distribution of ophthalmology, otolaryngology and dermatology classification was $43.48\%\;in\;ophthalmology,\;16.70\%\;in\;rhinology,\;5.72\%\;in\;laryngology,\;17.94\%\;in\;dermatology\;and\;16.17\%$ in otiatrics. 2. Ophthalmology group were $31.93\%$ males and $47.90\%$ females in 10 years old within. In treatment term, opthalmology patients who had treated for 1 month within was $59.70\%$. Strabismus and visual disorder was the most common ophthalmo-disease. 3. Rhinology group were $30.00\%$ males in 10 years old within and $21.56\%$ females in 21-30years old. In treatmentm, rhinology patients who had treated for 1 month within was $53.71\%$. Rhinitis and sinusitis was the most common rhinio-disease. 4. Otiatrics group were $30.54\%$ males in 41-50 years old and $31.78\%$ females in 51-60 years old. In treatment term, otiatries patients who had treated for 1 month within was $53.28\%$. Tinnitus, hearing loss and otitis media was the most common otiatrics-disease. 5. Laryngology group were $29.27\%$ males in 31-40 years old and $28.57\%$ females in 51-60 years old. In treatment term. Laryngology patients who had treated for 1 month within was $91.75\%$ Epipharyngitis and abnormal sensation pharyngolarylgeal region was the most common laryngo-disease. 6. Dermatology group were $39.82\%$ males and $39.79\%$ females in 21-30 years old. In treatment term, dematology patients who had treated for 1 month within was $83.55\%$. Acne and Pruritus was the most common ophthalmo-disease.