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      • KCI등재

        교합 유도 형태에 따른 저작근 활성도에 관한 연구

        김옥희,계기성,Kim, Ok-Hee,Kay, Kee-Sung 대한치과보철학회 1989 대한치과보철학회지 Vol.27 No.2

        The purpose of this study was to investigate the muscle activity of the group function occlusion and the changed canine guided occlusion using EM2. In this study, 13 subjects with group function occlusion and without temporomandibular disorders were selected, each subject was changed to the canine guided occlusion by forming the lingual ramps in the upper canines with light curing composite resin. The muscle activities of the anterior temporal and masseter muscle were recorded in the group function occlusion and immediately, one week, and two weeks after changing to the canine guided occlusion under the condition of maximum voluntary clenching in centric occlusion, lateral excursion, and during gum chewing. The results were as follows: 1. In case of maximum voluntary clenching in centric occlusion, the muscle activities of the anterior temporal and masseter muscle of working and balancing side didn't show any difference immediately after changing to the canine guided occlusion, one week after changing to the canine guided occlusion, one week after changing to it the muscle activities of the anterior temporal masseter muscle of working and balancing side were increased significantly, and two weeks after changing to it the muscle activities of the masseter muscle were increased significantly in comparison with the group function occlusion. 2. In case of maximum voluntary clenching in lateral excursion, the muscle activities of the anterior temporal and masseter muscle of working and balancing side were reduced significantly immediately after changing to the canine guided occlusion, one week after changing to it the muscle activities of the anterior temporal muscle of balancing side and of the anterior temporal and masseter muscle of working side were reduced significantly, and 2 weeks after changing to it the muscle activities of the anterior temporal and masseter muscle of working side were reduced significantly in comparison with the .group function occlusion. 3. During gum chewing, the muscle activities of the anterior temporal and masseter muscle of working and balancing side didn't show any difference immediately after changing to the canine guided occlusion, one week after changing to it the muscle activities of the masseter muscle of working and balancing side were increased significantly, and two weeks after changing to it only the muscle activities of masseter muscle of working side were increased significantly.

      • 생강성분 6-Paradol의 세포 독성 및 병리학적 연구

        김옥희,유은숙,정인경,이상섭,Kim, Ok-Hee,Yoo, Eun-Sook,Jung, In-Kyung,Lee, Sang-Sup 한국환경성돌연변이발암원학회 1998 한국환경성돌연변이·발암원학회지 Vol.18 No.1

        It is previously reported that 6-paradol can induce prolonged analgesia in experimental animals. In order to investigate the mutagenicity of 6-paradol, Ames Samonella/microsome plate assay was carried out with Salmonella typhimurium strains, TA 98, TA 100, TA 1535 and TA 1538, 6-Paradol was nonmutagenic in Salmonella typhimurium with and without rat liver microsomal activation. The rec assay with Bacillus substilis strains H 17 $rec^+$ and M 45 $rec^+$ was carried out ot test 6-paradol and other compounds (1-3 mg/disc) for DNA damaging activity, 6-Paradol was also nonmutagenic in DNA damaging activity. The relative size of the inhibition zone for 6-paradol was smaller than that of capsaicin. We have also determined the pathological effects of this compound on the various tissues of rats after administrating(i.p.) with increasing doses of 4, 8, 12, 16 mg/kg at 2 hour intervals and found no significant changes in terms of histology.

      • SCIESCOPUSKCI등재

        Nocardia SP . 에 의한 Δ4 - 3 - Ketosteroid 류의 산화

        김옥희,이상섭 ( Ok Hee Kim,Sang Sup Lee ) 생화학분자생물학회 1974 BMB Reports Vol.7 No.1

        Rationalizing of conformational or structural modification effect on 9α-hydroxylation of 17-ketosteroids which have Δ⁴-3-keto-system was attempted. When 6-methylandrost-4-ene-3,17-dione was incubated with Nocardia opaca, the rate of 9 a-hydroxylation was much slower than that of androst-4-ene-3,17-dione. In contrast, 9 a-hydroxylation of 6α-methylandrost-4-ene-3, 17-dione was faster than that of 6 ~-isomer. In addition to these two compounds, 19-norandrost-4-ene3,17-dione and 6,19-oxidoandrost-4-ene-3,17-dione were also compared with androst-4-ene-3,17-dione, and it was found that the rate of 9α-hydroxylation and B-ring rupturing of androst-4-ene-3,17-dione was fastest among tested steroids.

      • Nocardia Sp.에 의한 ${\Delta}^4$-3-Ketosteroid 류의 산화

        김옥희,이상섭,Kim, Ok-Hee,Lee, Sang-Sup 생화학분자생물학회 1974 한국생화학회지 Vol.7 No.1

        Steroid의 핵구조(ring structure)가 $9{\alpha}$-hydroxylation에 미치는 영향을 검토하기 위하여 $6{\beta}$-methylandrost-4-ene-3, 17-dione, $6{\alpha}$-methylandrost-4-ene-3, 17-dione, 19-norandrost-4-ene-3, 17-dione, androst-4-ene-3, 17-dione과 6, 19-oxidoandrost-4-ene-3, 17-dione 등 ${\Delta}^4$-keto-system을 갖고 있는 steroid를 Nocardia opaca 배양액중에 첨가하여 주고 $9{\alpha}$-hydroxylation 되는 과정을 살폈다. ${\Delta}^4$-keto-system에 $6{\beta}$-methyl group이 존재하면 현저히 hydroxylation의 속도가 느린 것을 발견하였다. Rationalizing of conformational or structural modification effect on $9{\alpha}$-hydroxylation of 17-ketosteroids which have ${\Delta}^4$-3-keto-system was attempted. When $6{\beta}$-methylandrost-4-ene-3, 17-dione was incubated with Nocardia opaca. the rate of $9{\alpha}$-hydroxylation was much slower than that of androst-4-ene-3, 17-dione. In contrast, $9{\alpha}$-hydroxylation of $6{\alpha}$-methylandrost-4-ene-3, 17-dione was faster than that of $6{\beta}$-isomer. In addition to these two compounds, 19-norandrost-4-ene-3, 17-dione and 6.19-oxidoandrost-4-ene-3, 17-dione were also compared with androst-4-ene-3, 17-dione, and it was found that the rate of $9{\alpha}$-hydroxylation and B-ring rupturing of androst-4-ene-3, 17-dione was fastest among tested steroids.

      • KCI등재후보

        쑥뜸치료가 암환자의 심박변이도에 미치는 영향

        김옥희,최정은,윤정원,유화승,Kim, Ok-Hee,Choi, Jung-Eun,Yoon, Jeung-Won,Yoo, Hwa-Seung 대한암한의학회 2011 大韓癌韓醫學會誌 Vol.16 No.1

        Objective : The study aims to investigate the effect of moxibustion treatments on autonomic nervous system function of cancer patients through the evaluation of heart rate variability (HRV) biofeedback testing. Materials and Methods : Six cancer patients from inpatient care unit of Dunsan Oriental Hospital, Daejeon University were given three moxibustion treatment sessions every other day over one week period on five Oriental Medicine meridian points CV4, CV6, CV12, KD1, and PC8. HRV biofeedback was conducted before and after each treatment sessions. Three areas of analyses were done from the test conducted; Time Domain Analysis, Frequency Domain Analysis and Autonomic Nervous System (ANS) balance analysis. Results : Time Domain Analysis has shown increased Standard Deviation of all Normal R-R Intervals (SDNN), and decreased Mean Heart Rate and Physical Stress Index (PSI) levels, with statistical significance (P<0.05). In Frequency Domain Analysis, series of moxa treatments have increased Total Power (TP), Very Low Frequency Oscillation Power (VLF), High Frequency Oscillation Power (HF), normalized HF values while decreasing Low Frequency Oscillation Power (LF), normalized LF and LF/HF ratio with statistical significance (P<0.05). The values of ANS activity, ANS balance, Stress resistance, Stress index, have also shown significant changes. For cardiac stability stroke volume power (SP) and Blood Vessel Tension (BVT) were followed, which were both increased after treatment. All changes were statistically significant (P<0.05). Conclusion : The results have shown a positive correlation between the moxibustion treatments and autonomic nervous system responses on cancer patients through the HRV biofeedback testing. This study suggests possible application of moxibustion treatments for managing ANS functions of cancer patients, although additional studies with larger population are necessary to confirm the data.

      • KCI등재후보

        무용동작치료 프로그램이 신경증 환자의 신체화, 우울, 불안, 감정표현불능에 미치는 효과

        김옥희(Ok Hee Kim) 대한스트레스학회 2009 스트레스硏究 Vol.17 No.2

        본 연구는 무용/동작 치료프로그램이 신경증 여성환자의 신체화, 우울, 불안, 감정표현불능증에 미치는 효과를 검정하고자 위함이며, 2005년 3월 15일부터 9월 30일까지 D시 소재하고 있는 두개 종합병원 정신과 외래치료를 받는 신경증 환자 실험군 15명, 대조군 15명, 총30명을 대상으로 한 비동등성 대조군 전후설계(Nonequivalent control-group pretest-posttest design)의 유사실험연구이다. 측정도구는 SCL-90-R의 신체화척도(Somatization), 우울척도(BDI), 불안척도 (Trait-State Anxiety), 감정표현불능증척도(TAS-20K)를 사용하고 자료처리 및 분석은 SPSS/WIN 10.0 프로그램을 이용하여 Chi-squre test, t-test, ANCOVA 로 하였다. 본 연구의 결과는 무용/동작치료 프로그램에 참여한 실험군은 참여하지 않은 대조군에 비해 신체화, 우울, 불안. 감정표현불능 점수가 통계적으로 유의하게 낮았으며, 이런 결과를 토대로 신경증 환자는 심신통합과 통찰력을 가지며 조기회복을 기대할 수 있다. 본 무용동작치료 프로그램은 Jung과 Freud 이론을 토대로 한 Chace와 Whitehouse의 무용치료방법론과 문헌고찰로써 구성개발 되었으며 음악, 댄싱, 심상, 하단 전호흡(명상), 이완, 무용역할극, 집단지지요법 등의 효과가 포함된 통합중재프로그램으로써 임상실무에서 정신 및 신체질환에 확대 적용되길 추천하며 생리측정의 지속적 연구를 제언한다. This study was to investigate the effects of the Dance Movement Therapy (DMT) program on somatization, depression, state anxiety and alexithymia and to suggest intervention of Neurosis. The study was done from March 15th, 2005 to September 30th, 2005. The subjects were 30 female neurosis outpatients. The research design a nonequivalent control group pretest-posttest design. The tools included somatization (SCL-90-R), depression (BDI), Trait-State anxiety and Alexithymia (TAS-20K) scale. Using the SPSS/WIN 10.0 program, the collected data was analyzed by Chi-square test, T-test and Ancova. This DMT program was development by theory of Frued and Jung, methodology of Marian Chace and Mary Whitehouse and it was constructed 5steps per 1session in total 18 sessions. There was a significant difference in the somatization, depression, state anxiety, alexithymia scores between experimental group and control group. Contents of program were included as follows: Emotional Eexpression Movement, Improvisation Dance Movement, Mirroing, Symbolic and Active Imagination (Authentic Movement), Relaxation Stretching, Deep Breathing, Dance Drama, Rhythmic Dancing and Group Therapy with Background Music. Therefore, this program is regarded as a synthetical intervention and it is expected that the patients make an early recovery. In future, it is recommended that physiologic research on DMT be conducted, continuously. (Korean J Str Res 2009;17:99∼109)

      • KCI등재
      • KCI등재
      • KCI등재
      • SCOPUSKCI등재

        연구 논문 : 인공 먼지로서 단분산 Polystyrene Latex Spheres (PLS)의 제조

        김옥희 ( Ok Hee Kim ),류동완 ( Dong Wan Ryu ),성동찬 ( Dong Chan Sung ),문희 ( Hee Moon ) 한국공업화학회 2012 공업화학 Vol.23 No.1

        potassium persulfate (KPS)와 sodium dodecyl sulfonate (SDS)를 각각 개시제와 안정제로 사용한 유화중합에 의하여 인공 먼지로 사용할 수 있는 polystyrene latex spheres (PLS)를 제조하였다. PLS입자의 크기를 조절하기 위한 변수로 반응온도와 개시제 및 안정제의 농도가 선택되었다. 반응온도의 증가에 따라 입자의 크기는 작아졌으며, KPS와 SDS의 농도를 변화시켜 PLS 입자의 크기 및 분포를 매우 미세하게 조절할 수 있었다. 본 연구에서 제조된 PLS입자는 변동계수(CV) 값이 7% 이하인 단분산이며, 0.1∼0.5 μm 범위에 있어 인조 먼지로 사용하기에 적합한 것으로 밝혀졌다. Polystyrene latex spheres (PLS) were prepared as artificial dusts by the emulsion polymerization with potassium persulfate (KPS) and sodium dodecyl sulfonate (SDS) as an initiator and a stabilizer, respectively. The reaction temperature and the concentration of the initiator and stabilizer were chosen as variables to control the PLS particle size. As temperature increased, the particle size decreased considerably. Furthermore, the PLS particle size and their size distributions can be controlled minutely by adjusting the concentrations of KPS and SDS. It is confirmed that the PLS prepared in this work is monodispersed with the coefficient of variance less than 7% and are in the range of 0.1∼0.5 μm, which are good for using as artificial dusts.

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