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김영미 ( Kim Young-mee ) 국제어문학회 2013 국제어문 Vol.57 No.-
Kim, Jong-sam`s poems are placed within the scars and memories of war. Kim, however, could not directly express this because he could not escape the war laden streets. Kim, in the context of outrages of war, expresses poetry as if to stutter or to experience language loss, or express his feelings with incongruent words. For such reasons, the academic and literary circles` predominant consensus is that Kim is a moderate, a classicist, or an aestheticist. I would like to begin my paper by raising skepticism towards such overwhelming consensus. Kim`s poems overflow with the desire to express what is unexpressable. Such inner chaos is rooted in the fear of the world which is generated by war. He was an un-prolific poet in that he did not produce many works and of the few most were short. He wandered in the land of silence. In his poetry, the silence is expressed as empty space. The poet was overly frugal with words. Words were replaced with empty spaces. They filled the places where words did not. The emptiness manifests as a desolate space. His is unlike that of Lao-tzu and Zhuangzi or Dhyana. He is not concerned with the transcendent. It seems that a psychological mutism towards fear and violence played a major part in Kim`s manifesting reality in his work. The poet was imprisoned in a world of not-speaking(or rather unable to speak), in other words in a world of speaking in silence. Nevertheless, the afflictions of an unfortunate era pours out from the depths of his soul in the language of poetry. The things he could not express directly comes alive from the hidden side of his work. The rejection of objects or the world created fear. His poems are apprehensive attempts at starting a conversation with the world he rejected. In this regard, readers are able to share the historic scars with the poet, providing solace for the broken past. On the other hand, however, his confined language is a barrier to his work. The short length and convoluted content of his poetry causes obstruction to communication.
Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration
김영미,Hye Kyung Kim,Hyo Jin Kim,이희우,주성아,최범규,권병세,Bong-Seon Kim,Jae-Bong Kim,임영탁,윤식 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.12
4-1BB, a member of the tumor necrosis factor receptor(TNFR) superfamily, is a major costimulatory receptorthat is rapidly expressed on the surface of CD4+ andCD8+ T cells after antigen- or mitogen-induced activation. The interaction of 4-1BB with 4-1BBL regulatesimmunity and promotes the survival and expansion ofactivated T cells. In this study, the expression of 4-1BBand 4-1BBL was examined during regeneration of themurine thymus following acute cyclophosphamideinducedinvolution. Four-color flow cytometry showedthat 4-1BB and 4-1BBL were present in the normal thymusand were preferentially expressed in the regeneratingthymus, mainly in CD4+CD8+ double-positive(DP) thymocytes. Furthermore, the CD4loCD8lo,CD4+CD8lo and CD4loCD8+ thymocyte subsets, representingstages of thymocyte differentiation intermediatebetween DP and single-positive (SP) thymocytes,also expressed 4-1BB and 4-1BBL during thymusregeneration but to a lesser degree. Interestingly,the 4-1BB and 4-1BBL positive cells among theCD4+CD8+ DP thymocytes present during thymus regenerationwere TCRhi and CD69+ unlike the correspondingcontrols. Moreover, the 4-1BB and 4-1BBLpositive cells among the intermediate subsets presentduring thymus regeneration also exhibited TCRhi/intand CD69+/int phenotypes, indicating that 4-1BB and4-1BBL are predominantly expressed by the positivelyselected population of the CD4+CD8+ DP and the intermediatethymocytes during thymus regeneration. RT-PCR and Western blot analyses confirmed the presenceand elevated levels of 4-1BB and 4-1BBL mRNAand protein in thymocytes during thymus regeneration. We also found that the interaction of 4-1BB with4-1BBL promoted thymocyte adhesion to thymic epithelialcells. Our results suggest that 4-1BB and4-1BBL participate in T lymphopoiesis associated withpositive selection during recovery from acute thymicinvolution.
김영미(Kim Young-mee) 한국시학회 2010 한국시학연구 Vol.- No.29
Anseo (Kim-uk) showed adventures and collapses in beginning modem Korean poems. The adventures was deeply related to experiences in Japan. To him, Japan was the space that he was able to meet three languages. This experience was cubic and dynamic. He experienced meeting with Korean, Japanese, and other languages(English, French, Esperanto etc.) in Japan. Japan was the space that many languages were mixed, and therefore diverse chemical reactions were able to happen with other languages. To Anseo, Japan was the space that eastern languages and western languages were crash with, and come into being. Anseo's poetic wandering was begin with the ross of established linguistic system. This was strengthened the external space, Japan. From experiences in Japan, Anseo was able to produce his poetics. But he was shown to accept poetic experiences in japan, and at the same time to get out of them. This was the very difficult process. This process means groping for poetic possibility of Korean. The pursuit of beauty in poetic language, female voice for it, and the attainment of music by rhythm were strengthened in Japan. Anseo's poetics got accomplished at the point of contact that was the reception and refusal though the external space. Thus he was able to leave many poems and poetic theories. They are meaningful up today. To Anseo, Japan was the space of despair and suffering for finding poetic language. In there eastern and western poems met with each other, a poet experienced the agony or delight together.
도파민 발현 세포주 CV(bDAT) 세포에서 항정신병 약물이 도파민 수송체 활성에 미치는 영향
김영미,이용성,이상훈,오동렬,양병환,조석신,남정현,Kim, Young-Mi,Lee, Yong-Sung,Lee, Sang-Hun,Oh, Dong-Yul,Yang, Byung-Hwan,Cho, Suck-Shin,Nam, Jung-Hyun 대한생물정신의학회 1997 생물정신의학 Vol.4 No.1
CV(bDAT) cell line, expressing dopamine transporter stably, has been established by transfection of CV-1 cells with bovine dopamine transporter cDNA. Using CV(bDAT) cells, the effects of various antipsychotic drugs on dopamine uptake activity were investigated. All of antipsychotic drugs tested, inhibited the [$^3H$]dopamine uptake into CV(bDAT) cells with $IC_{50}s$ in the low to mid micromolar range, implying that antipsychotic drugs may produce overflow of dopamine in the synaptic cleft of dopaminergic neuron.
베트남 결혼이주여성 부부의 임신·출산 및 양육준비를 위한 개별교육의 효과
김영미,조갑출,Kim, Youngmee,Cho, Kap-Chul 한국아동간호학회 2017 Child Health Nursing Research Vol.23 No.4
Purpose: The study was undertaken to see whether the culturally sensitive education for perinatal care using a face to face approach improves understanding of spouse's culture, knowledge of pregnancy and parenting skills, and self-efficacy among Korean husbands and Vietnamese wives. Methods: This study has a pre- and post-test study design conducted in a total of 13 couples who live in Seoul and agreed to participate. The education program consisted of lecture and hands on practice. The self-administered questionnaires and the checklist developed based on the educational purpose were used to assess the education effects. Results: The knowledge scores on Korean/Vietnamese culture, pregnancy and parenting skills as well as the performance scores on hand washing, pelvic strengthening, feedings and newborn bathing techniques were significantly improved in both husbands and wives after education, but pelvic floor exercises were improved only in wives. Conclusion: Overall, the individual education for culturally sensitive perinatal care was effective in our study participants.
단삼추출물의 Src-family Kinase 억제에 의한 항앨러지 효과
김영미,Kim, Young-Mi 대한약학회 2008 약학회지 Vol.52 No.5
In this study, the anti-allergic activity and mechanim of Salviae radix (SR) were investigated. The ethanol extract of SR showed significant inhibitory effect on degranulation from antigen-stimulated mast cells and it also inhibited the expression and secretion of TNF-${\alpha}$ and IL-4 in antigen-stimulated RBL-2H3 cells. In the mast cell-mediated local animal allergy model, it suppressed the passive cutaneous anaphylaxis in a dose-dependent manner. As its mechanism of action, SR inhibited the activating phosphorylation of Syk, a downstream signaling molecule of Src-family kinase, for the activation of mast cells. The results of the study indicate that the anti-allergic activity of SR is mediated by the inhibition of Src-family kinase in mast cells.
김영미,이영선 ( Young Mi Kim,Young Sun Lee ) 한국의류학회 1998 한국의류학회지 Vol.22 No.6
Since most clothing research has still centered around buying behavior, the importance of consumer behavior which exists outside the purchase context has been neglected. This orientation focusing solely on purchase-related processes is deficient as it cannot account for consumer behavior that is recreational or that occurs without a recognized consumption need. In this vein, clothing browsing behavior can be a significant variable that has effects on clothing purchase-related variables. So to speak, browsers do make purchases at times; delayed-action purchases, impulse purchases and browsers may provide other less informed people with product information. In this study, we used definition proposed by Bloch and Richins(1983), which defines non -purchase shopping(browsing) as the examination of merchandises of a store for recreational or informational purposes without a current intention to buy. The specific objectives of the study were to identify the dimensions of clothing non -purchase shopping and to determine the causal relationship among clothing involvement, non-purchase shopping, impulse buying, purchase quantity, opinion leadership. The questionnaire method was used and 366 questionnaires were analyzed. Results can be summarized as follows. First, the non-purchase shopping was divided into two dimensions such as recreational non-purchase shopping and informational non-purchase shopping. Of the two dimensions, recreational dimension explained the greater part than informational one. Second, it was revealed that clothing involvement was strongly positively related to non--purchase shopping, which influenced considerably on impulse buying, purchase quantity, and opinion leadership. In other words, clothing non-purchase shopping behaivor is very significant concept of clothing product category and has considerable effects on clothing buying though it occurs independently of purchase, so it seems that much more concern will be needed on this concept.
HOOCl-H<sub>2</sub>O Cluster의 구조와 결합에너지에 대한 ab initio 연구
김영미,성은모,Kim, Young-Mi,Sung, Eun-Mo 대한화학회 2008 대한화학회지 Vol.52 No.3
The geometrical structure, binding energy and vibrational frequencies of HOOCl-H2O cluster were investigated with MP2/6-311G(d,p) and MP2/6-311G(2d,2p) methods. The most stable conformer is skew HOOCl-H2O cluster and the binding energy was 46~48kJ/mol. The trans HOOCl-H2O cluster is less stable than skew form, but the binding energy is big enough to stablize the complex. The vibrational frequencies of skew and trans HOOCl-H2O cluster were calculated and compared with the spectrum of HOOCl.
산전 진단의 정확도를 높이기 위한 양수 세포에서의 고해상 G - 분염 염색체에 관한 연구
김영미,최수경,김혜영 ( Young Mi Kim,Soo Kyung Choi,Hei Young Kim ) 한국유전학회 1997 Genes & Genomics Vol.19 No.2
This study was performed to obtain high resolution chromosomes in amniotic fluid cell cultures using ethidium bromide (EtBr). EtBr is known to increase the percentage of high resolution chromosomes without changes of the chromosomal banding patterns. Five different concentrations of EtBr from 0 to 11.4 μg/ml were treated to determine the adequate EtBr concentration and the best result was obtained from the concentration of 11.4μg/ml producing 58.9% of the cells with high resolution chromosomes ranging 550-850 band levels. To confirm the effective EtBr exposure and harvest time on the formation of high resolution chromosomes, the harvest times were controlled 45 hrs and 48hrs after subculture and EtBr (11.4μg/ml) was added 3 hrs and 6 hrs before harvest. when the harvest time was 45 hrs after subculture and EtBr treatment time was 3 hrs, 52% of the cells with high resolution chromosomes was obtained. To determine the effect of EtBr concentration higher than 11.4μg/ml, five different concentrations between 0-17.1μg/ml were treated. As dosage of EtBr increased above 11.4μg/ml, there was an increase of sticky and conglomerated chromosomes. The total length of the chromosomes were significantly different (p<0.05) for the all band levels. The increasing rate of the length at high band level was 79% in an average when compared to low band level. Only the chromosomes 6,8,15 and 18 had the significantly different centromere index (p<0.05) for the different band level. Chromosome 2 was significantly different (p<0.05) in the relative length index for the different band level.