http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Occupational Neurologic Disorders in Korea
김양호,정경숙,윤영훈,오명숙 대한신경과학회 2010 Journal of Clinical Neurology Vol.6 No.2
This article presents a schematic review of the clinical manifestations of occupational neurologic disorders in Korea and discusses the toxicologic implications of these conditions. Vascular encephalopathy, parkinsonism, chronic toxic encephalopathy, cerebellar dysfunction, peripheral neuropathy, and neurodegenerative diseases are common presentations of occupational neurotoxic syndromes in Korea. Few neurotoxins cause patients to present with pathognomic neurologic syndrome. Detailed neurologic examinations and categorization of the clinical manifestations of neurologic disorders will improve the clinical management of occupational neurologic diseases. Physicians must be aware of the typical signs and symptoms of possible exposure to neurotoxins, and they should also pay attention to less-typical, rather-vague symptoms and signs in workers because the toxicologic characteristics of occupational neurologic diseases in Korea have changed from typical patterns to less-typical or equivocal patterns. This shift is likely to be due to several years of lowdose exposure, perhaps combined with the effects of aging, and new types of possibly toxicant-related neurodegenerative diseases. Close collaboration between neurologists and occupational physicians is needed to determine whether neurologic disorders are work-related.
당뇨유발백서에서 피하신경전기자극의 말초신경기능 개선효과
김양호,장미경,신민철,Kim, Yang-Ho,Chang, Mee-Kyung,Shin, Min-Chul 대한물리치료학회 2006 대한물리치료학회지 Vol.18 No.4
Purpose: This study aimed the effects of percutaneous electric nerve stimulation (PENS) applied to different parts of the streptozotocin-induced diabetic rats on the change of glucose and nerve. Methods: rats (ten weeks old) were selected as the subjects; the normal group was five rats, and the diabetes induction group II, III and IV were five rats, respectively, which were randomly sampled from the twenty-five streptozotocin-administered rats with more than $240\;d{\ell}/m{\ell}$ of blood sugar. For PENS, electric current with 2 Hz of stimulation frequency and $200\;{\mu}s$ of pulse duration was applied to the subjects for fifteen minutes a day, six days a week, for three weeks. Calculation of glucose and weight, and nerve conduction test were conducted forty-eight hours and three weeks after streptozotocin administration, respectively. Results: As for change of glucose and weight, the group III with stimulation to the acupoints and the group IV with stimulation to non-acupoints showed significant differences from the control group II (p<0.05). As for MNCV (motor nerve conduction velocity), the group III with stimulation to the acupoints showed significant differences from the group IV with stimulation to non-acupoints and the control group II (p<0.05). Conclusion: PENS had the effects of inhibiting increase of glucose, change of weight and decrease of nerve conductive function between the distal and proximal ends of the peripheral nerve in the STZ-induced diabetic rats.
Iron deficiency increases blood concentrations of neurotoxic metals in children
김양호,박상규 대한소아청소년과학회 2014 Clinical and Experimental Pediatrics (CEP) Vol.57 No.8
Iron deficiency affects approximately one-third of the world’s population, occurring most frequently inchildren aged 6 months to 3 years. Mechanisms of iron absorption are similar to those of other divalentmetals, particularly manganese, lead, and cadmium, and a diet deficient in iron can lead to excessabsorption of manganese, lead, and cadmium. Iron deficiency may lead to cognitive impairmentsresulting from the deficiency itself or from increased metal concentrations caused by the deficiency. Iron deficiency combined with increased manganese or lead concentrations may further affectneurodevelopment. We recently showed that blood manganese and lead concentrations are elevatedamong iron-deficient infants. Increased blood manganese and lead levels are likely associated withprolonged breast-feeding, which is also a risk factor for iron deficiency. Thus, babies who are breastfedfor prolonged periods should be given plain, iron-fortified cereals or other good sources of dietaryiron.