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비용 및 만성 비,부비동염 환자에서 잠재된 아스피린 과민성 천식의 유병률
박지원 ( Ji Won Park ),정덕희 ( Duk Hee Chung ),김석화 ( Seok Hwa Kim ),서범석 ( Beom Seok Seo ),민선양 ( Sun Yang Min ),최정희 ( Jeong Hee Choi ) 대한천식알레르기학회 2007 천식 및 알레르기 Vol.27 No.3
Background & Objective: Aspirin-intolerant asthma (AIA) is a distinct clinical syndrome characterized by aspirin sensitivity, asthma, and nasal polyposis (NP). The incidence of AIA in adult asthmatics is 8∼20%, and the prevalence of AIA among adult asthmatics with NP and/or chronic rhinosinusitis further increases to 30∼40%. However, the prevalence of subclinical AIA in patients with NP and/or chronic rhinosinusitis has rarely been investigated. Method: A total of 36 patients with NP and chronic rhinosinusitis who was scheduled for polypectomy were enrolled. All had no previous history of AIA. Lysine-aspirin bronchoprovocation tests were performed on all subjects before operation. Positive response was defined as a >15% fall in FEV1 from baseline. Result: Five of 36 patients (13.8%) showed positive responses to lysine-aspirin provocation tests (4 subject with NP+asthma and 1 with NP alone, P<0.05). There was a significant difference in the PC20 to methacholine between AIA+NP and NP+asthma groups (0.22±0.37 vs. 3.13±2.70 mg/mg, P<0.05), and peripheral blood eosinophil counts tended to increase from NP alone through NP+asthma to AIA+NP group (P<0.01). Conclusion: The prevalence of subclinical AIA in patients with NP and chronic rhinosinusitis was 13.8%, and AIA was especially more prevalent in the asthmatics with NP and chronic rhinosinusitis. (Korean J Asthma Allergy Clin Immunol 2007;27:176-180)
양동석 ( Dong-suk Yang ),윤영호 ( Young-ho Yoon ),김석화 ( Seok-hwa Kim ),박환용 ( Hwan-yong Park ) 한국정보처리학회 2011 한국정보처리학회 학술대회논문집 Vol.18 No.1
고령화 사회로 진입하고 있는 시점에 고령인구에 대한 복지정책 및 사회전반적인 대응 방안이 모색 되어져야할 시기이다. 특히, 고령인구 특성상 의료문제를 해결할 수 있는 효과적인 방법들의 연구가 시급하다. 그러한 문제를 해결하는 방안으로 U-헬스분야와 IT 분야 및 건설분야의 융합을 통한 효율적인 헬스케어 서비스 모델 개발이 요구되고 있다. 본 연구에서는 융합모델의 성공적인 결과 도출을 위한 모델의 구성과 추진 전략 등을 제안하였다.