양성 뇌종양의 분할정위 방사선치료

김대용(Dae Yong Kim),안용찬(Yong Chan Ahn),허승재(Seung Jae Huh),최동락(Dong Rak Choi),김종현(Jong Hyun Kim),이정일(Jung Il Lee),박관(Kwan Park),남도현(Do-Hyun Nam),김문경(Moon Kyung Kim) 대한방사선종양학회 1998 Radiation Oncology Journal Vol.16 No.2

목 적 : 재현성이 높은 정위적 고정장치의 개발로 인하여 보편화되고 있는 분할정위 방사선치료는 정확히 표적부위에 방사선을 조사하면서 주위 정상조직에서의 급격한 선량감소를 보이며, 분할치료를 시행함으로서 부작용을 최소화할 수 있는 치료기법이다. 이에 저자들은 분할정위 방사선치료에 대한 초기 임상경험에 대한 예비적 결과를 보고하고자 한다. 대상 및 방법 : 1995년 8월부터 1996년 12월까지 총 15명의 양성 뇌종양 환자들을 대상으로 분할정위 방사선치료를 시행하였다. 환자의 연령분포는 6-70세(중앙값 40세)로 7명 대 8명의 남녀 비를 나타내었다. 진단명에 따라 뇌하수체 선종 10명, 두개인두종 2명, 청신경초종 1명, 뇌수막종 2명이었다. Gill-Thomas-Cosman 프레임과 3차원 다회전치료를 이용하여 일일 선량 2Gy를 90- 100%의 등선량표면 기준으로 조사하였다. 콜리메이터는 직경 26-70mm의 원형을 사용하였다. 결 과 : 6-20개월의 비교적 짧은 추적조사기간이나 방사선학적 영상촬영 검사상 1명의 추적조사실패를 제외하고 7명이 완전관해 내지 병변의 축소를 나타내었으며, 1명의 병변내 괴사, 1명의 석회화, 5명의 무변화 등 전통적인 방사선치료와 유사한 결과를 보였다. 경미한 급성반응외 뇌신경마비나 뇌조직괴사의 부작용은 관찰되지 않았다. 치료 시마다 측정하는 두피-헬멧 거리의 오차는 평균 1.1±0.6mm이었다. 결 론 : 분할정위 방사선치료의 고정장치는 비교적 재현성이 높은 치료시스템으로서 뇌종양의 치료로서 안전하며 효과적인 치료기법으로 판단된다. 향후 일회 및 총 선량 등의 치료일정은 지속적인 임상연구로 풀어나가야 할 과제이다. Purpose : With the development of stereotactic immobilization systems capable of reliable serial repositioning, fractionated stereotactic radiation therapy (FSRT) offers the potential for an improved treatment outcome by excellent dose delivery, and dose distribution characteristics with the favorable radiobiological properties of fractionated irradiation. We describe our initial experience using FSRT for the treatment of intracranial benign tumor. Materials and Methods : Between August 1995 and December 1996, 15 patients(7 males and 8 females aged 6-70 years) were treated with FSRT. The patients had the following diagnosis : pituitary adenoma(10) including one patient who previously had received radiotherapy, craniopharyngioma (2), acoustic neurinoma (1), meningioma (2). Using the Gill-Thomas-Cosman relocatable head frame and multiple non-coplanar therapy, the daily dose of 2Gy was irradiated at 90% to 100% isodose surface of the isocenter. Th e collimator sizes ranged from 26mm to 70mm. Results : In all patients except one follow -up lost, disease was well- controlled. Acute complication was negligible and no patient experienced cranial nerve neuropathies and radiation necrosis. In overall patient setup with scalp measurements, reproducibility was found to have mean of 1.1±0.6mm from the baseline reading. Conclusion : Relocatable stereotactic system for FSRT is highly reproducible and comfortable. Although the follow -up period was relatively short, FSRT is considered to be a safe and effective radiation technique as the treatment of intracranial tumor. But the fractionation schedule(fraction size, overall treatment time and total dose) still remains to be solved by further clinical trials.

공기 압축기의 피스톤용 알루미늄 합금 소재 개발

김순경(Soon-Kyung Kim),김문경(Moon-Kyung Kim) 한국기계가공학회 2008 한국기계가공학회지 Vol.7 No.1

It is important not only to reduce the casting defects of piston but also to improvement in the mechanical properties(hardness) of piston for the air compressor. The blow hole is typical casting defects in the conventional cast of aluminium alloy(AC8A-T6) piston. Because of the heat treatment method, mechanical properties of the aluminium alloy for piston was decided on the heat treatment method and cycle. Therefore, we tested on the development of mechanical properties and on the casting defects of piston for the air compressor in accordance with the heat treatment and casting condition. After the heat treatment and casting was carried out as several times, and was compared with the imported piston. As a result of several investigations; microstructure, hardness and casting defects of piston was changed under the influence of the heat treatment and casting method. When the cooling rate was controlled and the uni-cast method used, it bas the same mechanical properties and microstructure.

수평한 유입구를 가진 원형 노즐 임팩터의 포집효율에 관한 연구

김문경(Moon-Kyung Kim),김원근(Won-Geun Kim),김창겸(Chang-Kyum Kim),송대현(Dae-Hyun Song),우상희(Sang-Hee Woo),육세진(Se-Jin Yook) 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.12

로봇 복강경하 광범위 자궁경부절제술

김문경 ( Moon Kyung Kim ),최철훈 ( Chel Hun Choi ),송태종 ( Tae Jong Song ),박황신 ( Hwang Shin Park ),이유영 ( Yoo Young Lee ),김태중 ( Tae Joong Kim ),이정원 ( Jeong Won Lee ),이제호 ( Je Ho Lee ),배덕수 ( Duk Soo Bae ),김병기 ( 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.6

To present a case of successful robotic assisted radical trachelectomy. A nulliparous woman with early cervical cancer underwent a laparoscopic radical trachelectomy and pelvic lymphadenectomy with the da Vinci robot (Intuitive Surgical Inc., Sunnyvale, CA). After the pelvic lymph nodes were found negative on frozen section, the parametria, paracolpia and uterosacral ligaments were dissected transabdominally sparing the ascending branches of the uterine arteries. Cervical transection and vaginal closure were performed transvaginally. Surgical time was 450 min. No perioperative complications were noted. Robotic laparoscopic radical trachelectomy may bridge the gap between laparotomy and laparoscopy for radical trachelectomy.

자동차 보수도장용 수용성 도료의 도장특성에 관한 연구

김순경(Soon-Kyung Kim),김문경(Moon-Kyung Kim) 한국기계가공학회 2008 한국기계가공학회지 Vol.7 No.4

This paper investigates the correlation between surface roughness and gloss of aluminium sheet painted waterborne paint. One customer criterion of automotive quality is the as-painted appearance of the final products. Especially, the current emphasis on control of surface roughness of sanded aluminium sheet has been prompted by the automotive industry's concern with the as-painted appearance. because the influence of such characteristics on paintability, and painted appearance is important in defining outer panel requirements for automobile. This paper is dedicated primarily to the issue of painted appearance and reviews for improvement of roughness. The conclusions are obtained as follows ; 1) Painted aluminium sheet appearance is strongly affected by surface roughness of base-metal and influenced by sand paper and sanding method. 2) The painted appearance of aluminium sheets was determined and related to surface roughness parameters, combination of sand paper.

Analysis of the Inter- and Intra-treatment Isocenter Deviations in Pelvic Radiotherapy With Small Bowel Displacement System

김문경,김대용,안용찬,허승재,임도훈,신경환,이규찬,Kim Moon Kyung,Kim Dae Yong,Ahn Yong Chan,Huh Seung Jae,Lim Do Hun,Shin Kyung Hwan,Lee Kyu Chan The Korean Society for Radiation Oncology 2000 Radiation Oncology Journal Vol.18 No.2

목적 : small bowel displacement system (SBDS)을 이용한 골반부 방사선 치료시 치료간(intertreatment) 및 치료중(intratreatment) 중심점 위치변동의 편차를 분석하고, 그 결과를 임상적으로 이용하고자 하였다. 대상 및 방법 :자궁경부암 7명, 직장암 4명의 총 11명의 환자를 대상으로 electronic portal imaging device (EPID)를 이용하여 302건의 후-전문(postero-anterior port) 영상과 232건의 측문(lateral port) 영상을 얻었다. 모든 환자는 복와위 자세로 하복부에 SBDS를 사용하였다 방사선 조사야의 중심점과 배율을 맞추기 위하여 5개의 금속 기준점을 영상탐지판(image detection unit)에 부착시켰으며, EPID 영상의 골 기준점(bony landmark)을 정하여 모의치료시 촬영한 영상과 비교하여 정렬시킨 후 우-좌문, 두-미문, 그리고 후-전문 방향으로 중심점의 이동방향 및 거리를 분석하였다. 결과 : 우-좌문, 두-미문, 그리고 후-전문 방향으로의 치료간 중심점 이동의 평균값은 각각 1.2 mm ($\pm$1.6 mm), 1.0mm ($\pm$3.0 mm), 0.9 mm ($\pm$4.4 mm)이었으며, 각 방향으로의 5 mm 이상의 치료간 중심점 이동은 각각 2, 12, 24$\%$, 그리고 10 mm 이상의 치료간 중심점 이동은 각각 0, 0, 5$\%$이었다 큰 폭의 위치변동을 보인 방향은 후-전문 방향이었으며, 최대값은 11.5 mm 이었다. 우-좌문, 두-미문, 그리고 후-전문 방향으로의 치료중 중심점 이동의 평균값은 각각 0 mm ($\pm$0.9 mm), 0.1 mm ($\pm$1.9 mm), 0 mm ($\pm$1.6 mm)이었다. 5 mm 이상의 치료중 중심점 이동은 각각 0, 1 , 1$\%$이었다. 결론 : SBDS를 이용한 골반부 방사선 조사시 폭과 빈도가 가장 큰 치료간 위치변동은 후-전문 방향이므로, 측면의 후-전문 방향으로 추가적인 여유를 두는 것이 바람직할 것으로 판단된다. Purpose : To evaluate the e지ent and frequency of the inter- and intra-treatment isocenter deviations of the whole pelvis radiation field in using small bowel displacement system (SBDS). Methods and Materials : Using electronic portal imaging device (EPID), 302 postero-anterior 232 lateral portal images were prospectively collected from 11 patients who received pelvic radiation therapy (7 with cervix cancer and 4 with rectal cancer). All patients were treated in prone position with SBDS under the lower abdomen. Five metallic fiducial markers were placed on the image detection unit for the recognition of the isocenter and magnification. After aligning the bony landmarks of the EPID images on those of the reference image, the deviations of the isocenter were measured in right-left (RL), cranio-caudal (CC), and PA directions. Results : The mean inter-treatment deviation of the isocenter in each RL, CC, and PA direction was 1.2 mm ($\pm$ 1.6 mm), 1.0 mm ($\pm$3.0 mm), and 0.9 mm ($\pm$4.4 mm), respectively. Inter-treatment isocenter deviations over 5 mm and 10 mm in RL, CC, and PA direction were 2, 12, 24$\%$, and 0, 0, 5$\%$, respectively. Maximal deviation was detected in PA direction, and was 11.5 mm. The mean intratreatment deviation of the isocenter in RL, CC, and PA direction was 0 mm ($\pm$0.9 mm), 0.1 mm ($\pm$ 1.9mm), and 0 mm ($\pm$1.6 mm), respectively. All intra-treatment isocenter deviations over 5 mm in each direction were 0, 1, 1$\pm$, respectively. Conclusions : As the greatest and the most frequent inter-treatment deviation of the isocenter was along the PA direction, it is recommended to put more generous safety margin toward the PA direction on the lateral fields if clinically acceptable in pelvic radiotherapy with SBDD.

중금속 오염 준설토의 토양으로서의 유효활용을 위한 선별수준 생태위해도평가

김문경(Moon Kyung Kim),김기범(Ki Beum Kim),최용주(Yong Ju Choi),남경필(Kyoung Phile Nam) 大韓環境工學會 2016 대한환경공학회지 Vol.38 No.5

본 연구에서는 중금속의 생태독성자료를 통해 준설토의 육상 재활용을 위한 screening-level 생태위해도 평가를 수행하였다. 대상 중금속 6종(Cu, Zn, Cd, Pb, Cr, Ni)의 독성자료는 USEPA의 ECOTOX를 통해 수집하였으며, 선별과정을 거쳐 생태위해도 평가에 사용하였다. 각 중금속의 예측무영향농도는 독성자료의 획득이 가능한 육상 수용체의 종 수에 따라 확률론적 방법(Cu, Zn, Cd)과 결정론적 방법(Pb, Cr, Ni)을 통해 도출하였다. 현장 채취 준설토에서 발견되는 중금속 실제오염농도와 예측무영향농도와의 비교를 통해 생태위해도를 계산하였으며 Cu, Zn, Cr, Pb, Ni의 위해도가 1을 초과하여 생태독성학적 위해도가 존재할 수 있는 가능성을 확인하였다. 따라서 재활용 부지의 생태위해도를 고려하였을 때 해당 중금속 오염 준설토를 활용하기 위해서는 중금속 정화 또는 보다 높은 수준의 생태 위해도평가가 선행되어야 할 것으로 판단된다. This study conducted a screening-level ecological risk assessment for heavy metals in dredged sediment for recycling in terrestrial environment. Toxicological information of six heavy metals (i.e., Cu, Zn, Cd, Pb, Cr, and Ni) was collected from ECOTOX of US Environmental Protection Agency, and screened and qualified for the use in the screening-level ecological risk assessment. According to the number of terrestrial ecological receptors for which toxicological information is available, PNEC (Predicted No Effect Concentration) of each heavy metal was derived using either stochastic approach (for Cu, Zn, and Cd), or deterministic approach (for Pb, Cr, and Ni). Hazard quotients of the six heavy metals were derived for a field-collected dredged sediment using the PNEC derived and the PEC (Predicted Environmental Concentration) determined for the dredged sediment. The HQs of Cu, Zn, Cr, Pb and Ni were higher than unity indicating a possibility of ecological risk of the five heavy metals when the dredged sediment is applied in terrestrial environment. Accordingly, remediation processes or a higher-level ecological risk assessment would be needed for the recycling of the material.

냉각압연 가공용 자동 형상제어장치의 특성에 관한 연구

김문경,전언찬,김순경,Kim, Moon-Kyung,Jeon, Eon-Chan,Kim, Soon-Kyung 대한기계학회 1996 大韓機械學會論文集A Vol.20 No.9

Flatness of cold rolled strip is vital to the quality of the product and productivity of the mill. Therefore, in recent year requirement for flatness control in strip rolling have become increasingly severe. The necessity for more accurate automatic gauge control and automatic flatness control(AFC) has increased by customer's requirement for cold rolled steel sheets with thinner gauge and better flatness quality. In this paper, the performance and functions of AFC system installed on the 4 hi-reversing mill has been investigated under actual conditions. The test results are as follows : The more strip thickness is thick, the smaller the I-value. The I-value is a strain measured by stressometer. Complex distributions of strip tension are controlled to remove not only a quarter buckle but also a simple center wave and edge wave. The defects caused by poor flatness have been drastically decreased. And a proper coolant temperature for work roll cooling system on the AFC system is about $50~55^{\circ}C$.

전기응집 반응을 이용한 PFOA의 제거에 관한 연구

김문경 ( Moon-kyung Kim ),김태연 ( Taeyoun Kim ),김태경 ( Tae-kyoung Kim ),조경덕 ( Kyung-duk Zoh ) 한국물환경학회(구 한국수질보전학회) 2018 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2018 No.-

304 스테인리스강의 용접부위의 부식특성에 관한 전기화학적 평가

문경만(Kyung-Man Moon),김윤해(Yun-Hae Kim),김종도(Jong-Do Kim),이명훈(Myung-Hoon Lee),김진경(Jin-Gyeong Kim) 한국해양공학회 2009 韓國海洋工學會誌 Vol.23 No.4

Two kinds of welding methods are used for austenitic 304 stainless steel: laser welding and TIG welding. The difference in the corrosion characteristics if the welded zone between these two welding methods was investigated using electrochemical methods, such as corrosion potential measurements, polarization curves, cyclic voltammograms, etc. The Vickers hardnesses if all the welded zones (WM: Weld Metal, HAZ: Heat Affected Zone, BM: Base Metal) showed relatively higher values in the case if laser welding than for TIG welding. Furthermore, the corrosion current densities if all the welding zones showed lower values compared to TIG welding. In particular, the corrosion current density if the HAZ with TIG welding had the highest value if all the welding zones, which suggests that chromium depletion due to the formation if chromium carbide appears in the HAZ, which is in the range of the sensitization temperature. Thus, it can easily be corroded with a more active anode. Consequently, we found that the corrosion resistance if all of the welding zones for austenitic 304 stainless steel could apparently be improved by using Loser welding.