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권오근,김성환,천병열,박채규,손건호,Kwon, Oh-Geun,Kim, Sung-Hwan,Chun, Byung-Yeol,Park, Chae-Kyu,Son, Kun-Ho 한국생약학회 1999 생약학회지 Vol.30 No.3
To evaluate antimicrobial activity of Moutan cortex the compounds isolated from $CHCl_3$ and EtOAc fractions of Moutan cortex were subjected to eight pathogenic strains. Benzoic acid, witch was identified from the $CHCl_3$ fraction, had MICs with $625{\sim}1,250\;{\mu}g/ml$ against all of the strains tested. Methyl gallate, p-hydroxy benzoic acid, gallic acid and $1,2,3,4,6-penta-O-gallyol-{\beta}-D-glucose$, which were identified from the EtOAc fraction, showed the antimicrobial activity, and the methyl gallate had the widest antimicrobial activity with MICs of $625{\sim}5,000\;{\mu}g/ml$ against all strains tested. p-Hydroxy benzoic acid showed MICs of $1,250{\sim}2,500\;{\mu}g/ml$ against all of the strains tested except C.albicans. Gallic acid had the best antimicrobial activities with MICs against the Shigella dysenteriae and Streptococcus mutans-strains of 78.1 and $312.5\;{\mu}g/ml$, respectively, but not against the C. albicans. And $1,2,3,4,6-penta-O-gallyol-{\beta}-D-glucose$ had the best antimicrobial activitie with MICs against the B. cereus, Staph. epidermidis and C. albicans strains of 39.1, 39.1 and $156.3\;{\mu}g/ml$, respectively, but not against the E. coli and Shig. Dysenteriae.
국화(Chrysanthemum morifolium)꽃으로부터 Flavonoid의 분리 및 동정
김형근 ( Hyoung-geun Kim ),고정환 ( Jung-hwan Ko ),이영근 ( Yeong-geun Lee ),박하승 ( Ha-seung Pak ),김동찬 ( Dong-chan Kim ),손국성 ( Kuk-seong Son ),백윤수 ( Yun-su Baek ),권오근 ( Oh-keun Kwon ),신학기 ( Hak-ki Shin ),백남인 ( 한국응용생명화학회 2016 Journal of Applied Biological Chemistry (J. Appl. Vol.59 No.4
국화(C. morifolium)의 꽃을 80 % MeOH 수용액으로 추출한뒤, 감압농축한 추출물을 EtOAc, n-butyl alcohol 및 물분획으로 나누었다. EtOAc 분획과 n-butyl alcohol 분획에 대하여SiO2 및 ODS column chromatography를 반복 실시하여 4종의 flavonoid를 분리, 정제하였다. Nuclear magnetic resonance, infrared spectrometry 및 FAB-MS data를 해석하여, 화합물 1-4를 각각 apigenin, acacetin, cosmetin (apigenin-7-O-β-Dglucopyranoside), acacetin-7-O-β-D-glucoside으로 구조 동정 하였다. Chrysanthemum morifolium flowers were extracted with 80 % aqueous MeOH, and the concentrated extract was partitioned into EtOAc, n-butyl alcohol (n-BuOH), and water fractions. The repeated silica gel and octadecyl silica gel column chromatographies for the EtOAc and n-BuOH fractions led to isolation of four flavonoids. The chemical structures of the compounds were determined as acacetin (1), apigenin (2), apigenin- 7-O-β-D-glucopyanoside (3), acacetin-7-O-β-D-glucopyranoside (4) based on spectroscopic data analyses including nuclear magnetic resonance, mass spectrometry, and infrared spectrometry.
과도안정도와 미소신호안정도 관점에서 국내 전력계통의 임계관성계수 평가
백종오(Jong-Oh Baek),정인주(In-Joo Jeong),하정민(Jung-Min Ha),맹창엽(Chang-Yeop Maeng),권오근(Oh-Geun Kwon),이배근(Bae-Geun Lee),김수배(Soobae Kim) 대한전기학회 2019 전기학회논문지 Vol.68 No.9
The increase of inverter-based renewable energy sources reduces inertia constant of power systems and the loss of the system inertia may cause power system stability problems. To ensure a secure energy delivery system, these problems should be analyzed thoroughly from various perspectives about power system stability. This paper presents the estimation of the critical inertia of Korean power systems, which is the minimum amount of inertia required to maintain power system dynamic securities. The estimation has been made by gradually reducing the system inertia of Korean power systems and then by analyzing the change of dynamic securities in terms of transient and small signal stabilities. In the transient stability aspect, the decrease of critical clearing time(CCT) has been analyzed with four different reduced inertial models of Korean power systems. With the small signal stability perspective, the change of the system damping ratio has been studied. Based on the results from the stability studies, the critical inertia has been determined and it can be considered as the indirect limit of renewable energy shares in Korean power systems.
적색 국화의 화색발현에 있어 고온에 민감한 생육 단계와 품종별 고온적응성 비교
허은주(Eun Joo Huh),신학기(Hak Ki Shin),최성렬(Seong Youl Choi),권오근(Oh Geun Kwon),이영란(Young Ran Lee) 한국원예학회 2008 원예과학기술지 Vol.26 No.4
국화의 화색발현에 있어 고온에 민감한 화아발달단계를 구명하고자 국화의 화아 발달 과정을 4단계로 나누어 고온 처리하였다. 그 결과 꽃봉오리가 터지는 시기에 고온에 접하였을 때 안토시아닌 함량이 가장 많이 감소되어 ‘Relance’의 경우 35/20℃ 처리시 안토시아닌 함량이 25/20℃ 처리구의 48% 수준으로 감소하였다. 고온에 대한 화색의 반응은 ‘Relance’와 ‘Wembley’에서 다소 다르게 나타났다. ‘Relance’의 안토시아닌 함량은 35/20℃에 접할 경우 25/20℃에 비해 약 43.4% 감소한 반면 ‘Wembley’는 약 10% 정도만 감소하여 고온의 영향을 적게 받는 것으로 나타났다. 안토시아닌 생합성 유전자의 발현을 분석한 결과 dihydroflavonol reductase(DFR)와 anthocyanin synthase(ANS)는 두 품종 모두에서 고온에 의해 발현이 현저히 감소하였다. 그러나 고온에 의한 flavanone 3-hydoxylase(F3H)의 발현의 감소 정도는 ‘Wembley’ 품종에서 다소 적게 나타났다. The study showed that among the four different flower developmental stages, anthocyanin content was extremely decreased by high temperature when plants were exposed at bud opening stage for seven days. During that stage, anthocyanin content of ‘Relance’ flowers subjected to 35/20℃ was about 48% that of flowers exposed to 25/20℃. On the other hand, the color response to high temperature differed between two red chrysanthemum cultivars, ‘Relance’ and ‘Wembley’. Anthocyanin content of ‘Relance’ was reduced by 43.4% at high temperature (35/20℃) when compared with those exposed to 25/20℃. However, that of ‘Wembley’, which was less affected by temperature, resulted in only 10% reduction at 35/20℃. The gene transcripts, especially dihydroflavonol reductase (DFR) and anthocyanin synthase (ANS), were reduced extremely by high temperature in both cultivars. Reduction in flavanone 3-hydoxylase (F3H) expression by high temperature was less in ‘Wembley’ than in ‘Relance’.