2P-301 Micro-Patterning of Filamentous Bacteriophages through Self-Assembly Process

곽민지,허광 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.0

피부장벽개선을 위한 글루코실세라마이드와 커큐민의 항산화와 항염증 및 콜라겐활성 탐색

곽민지,고유림,이재현,이해선,배경미,김태완 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

글루코실세라마이드의 피부장벽 및 아토피개선 효과를 증대하기 위한 커큐민, 비타민C, 피쉬콜라겐 혼합제품의 개발가능성을 제시하고자 본 연구를 수행하였다. ABTs 및 DPPH assay로 항산화 활성능을 측정한 결과, ABTs assay IC50은 글루코실세라마이드 250.77 μg/mL, 커큐민 31.41 μg/mL, 비타민C 21.62 μg/mL, DPPH assay IC50 커큐민 35.46 μg/mL였으며, 총폴리페놀 함량도 커큐민이 비교적 높았다. RAW 264.7 대식세포와 HS68 섬유아세포를 배양하여 MTT assay를 실시한 결과, 글루코실세라마이드 30 μg/mL, 커큐민 7.5 μg/mL, 비타민C 400 μg/mL, 피쉬콜라겐 1600 μg/mL에서 세포 생존도 80% 이상으로 세포의 증식과 생존양상이 확인되었다. 개별시료와 혼합시료의 NO 생성 억제능을 비교한 결과, 커큐민 7.5 μg/mL은 60% 이하, 글루코실세라마이드 15 μg/mL은 70% 이하, 글루코실세라마이드 15 μg/mL+커큐민 7.5 μg/mL+비타민C 100 μg/m+피쉬콜라겐 1600 μg/mL 혼합시료에서 25% 이하로 억제되어 혼합시료가 항염증효과가 높았으며, 혼합시료에서 Western blot을 통한 Collagen I 발현증가도 일부 확인하였다. 본 연구를 통해 글루코실세라마이드와 커큐민 혼합물의 항산화, 항염증 효과 및 Collagen I 발현촉진효과가 확인하였으며, 피부장벽개선을 위한 기능성식품 또는 아토피 피부염 치료제의 소재로 활용될 수 있을 것으로 기대된다.

온라인 라이브 스트리밍 공연에서의 촉각 자극이 관람객의 심리적 경험에 미치는 영향

곽민지,이상원 한국감성과학회 2021 춘계학술대회 Vol.2021 No.-

Currently, online live streaming concert has gained increasing attention due to prolonged COVID-19. Various online platform services such as Youtube, VLIVE is actively adopting such form of concert. While such alternative form of concert is gaining broad attention and popularity, viewers’ experience is still limited to passive experience although some of the platforms(e.g. Weverse) provided by entertainment companies are providing visual interaction using cheering stick. Regarding such limit current form of online live streaming concert is facing, this study aims to investigate how vibration stimulation affects viewer’s psychological experience while watching online live streaming concert.

전문대학 비교과 프로그램 인식차이를 통한 방향성 탐색

곽민지,정해수 한국미래교육학회 2020 미래교육연구 Vol.10 No.2

본 연구는 미래사회 인재를 양성하기 위한 전문대학의 학습자, 교수자의 관점에서 기초학습능력 지원 요구를 파악하고 이를 통해 비교과 프로그램의 체계적 지원방안을 모색하고자 하였다. 연구결과, 기초학습 역량의 중요도의 경우 교수자가 학습자보다 더 중요하다고 인식하였다. 비교과 프로그램별 인식 차이 결 과, 기초학습지원 프로그램에서는 전공기초, 학습클리닉 프로그램, 외국어지원 프로그램에서 학습자보다 교수자가 더 중요하다고 인식한 것으로 드러났다. 또한 대학지원 생활 프로그램의 경우에도 교수자가 더 중요하다고 인식한 것으로 드러났다. 마지막으로 취업지원 프로그램의 경우 어깨동무튜터링, 생생멘토링, 전공으뜸이 프로그램 모두에서 교수자가 더 중요하게 인식하는 것으로 나타났다. 결과적으로 모든 프로그 램에서 교수자의 인식이 학습자의 인식보다 높게 나타났다. 연구결과를 기반으로 도출된 전문대학 학습자 의 기초학습역량 강화 및 비교과 프로그램에 대한 제언은 다음과 같다. 첫째, 학습자들을 대상으로 기초학 습역량 인식 개선을 위한 지원방안을 강구해야 한다. 둘째, 기초학습역량 향상을 위한 대학 시스템 구축이 필요하다. 세부적으로 첫째, 기초학습향상을 지원하는 인력풀 확보 및 인센티브 제공 등 유인책이 제공되 어야 한다. 둘째, 대학 특성에 맞는 비교과 프로그램이 개설되어야 한다. 셋째, 비교과 프로그램은 전공별, 학습자 특성에 맞는 과정으로 체계화되어야 한다. 넷째, 학습자 중심형 비교과 프로그램으로 개선될 필요 가 있다. 다섯째, 비교과 프로그램의 선순환 구조를 형성할 필요가 있다. The purpose of this study was to identify the needs of supporting on basic learning ability from the perspectives of learners and instructors of junior colleges, and to seek systematic support measures for extra curricular programs. The results showed that the importance of basic learning competencies was recognized as more important by instructors than by learners. As a result of checking the difference in recognition on extracurricular programs, it was revealed that the instructors perceived that the basic learning support program was more important than the learners in the basic basics, the learning clinic program, and the foreign language support program. In the case of university-sponsored living programs, the instructor also found it more important. Lastly, in the case of employment support programs, instructors perceived 'shoulder tutoring, live mentoring, and majoring majors programs' as more important than leaners did. In all programs, the teacher's perception was higher than the learner's perception. Therefore, first, Measures targeting learners should be sought to improve awareness of basic learning competencies. Second, it is necessary to establish a university system to improve basic learning competencies. In detail, first, incentives should be provided, such as securing a pool of workers and providing incentives to support basic learning. Second, extracurricular programs suitable for university characteristics should be established. Third, extracurricular programs should be organized into processes that suit each major and learner's characteristics. Fourth, it should undergo improvement as learner-oriented extracurricular programs. Fifth, it is necessary to form a virtuous cycle of extracurricular programs.

The Effect of Direct Communication between Emergency Physicians and Interventional Cardiologists on Door to Balloon Times in STEMI

곽민지,김규석,이중의,신중호,서길준,조영석,연태진,정우영,채인호,최동주,Christopher C. Lee,Adam J. Singer 대한의학회 2008 Journal of Korean medical science Vol.23 No.4

We developed an institutional protocol mandating emergency physicians to contact the interventional cardiologist directly in all cases of ST-segment elevation myocardial infarction (STEMI) and hypothesized that this would reduce door-to-balloontimes (DTBT). From January 2004 to July 2006, 208 patients with STEMI were treated with primary percutaneous coronary intervention (PCI). A total of 144 patients were treated before implementing the new protocol (‘‘before’’) and 64 patients were treated after the implementation (‘‘after’’). The DTBT was significantly reduced from 148±101 min to 108±56 min (p<0.05). While only 25% of the ‘‘before’’ patients received PCI within 90 min after arrival, 50% of the ‘‘after’’ patients received PCI within 90 min (p<0.05). There were no significant differences between two groups in other outcomes (postprocedural TIMI flow, mortality, subsequent stroke, heart failure, shock, reinfarction, length of stay in intensive care unit, and the total hospital length of stay). In conclusion, mandating emergency physicians to directly notify interventional cardiologists of all STEMI patients reduces DTBT.

[근로조건] 직장 내 괴롭힘의 ‘인지’ 기준에 대한 검토

곽민지 (주)중앙경제 2024 노동법률 = (The) labor law Vol.- No.393

Displaced Double-Layered Lateral Meniscus That Mimicked the Bucket-Handle Tear: a Case Report

곽민지,김선기,김기준,이범식,강준 대한자기공명의과학회 2016 Investigative Magnetic Resonance Imaging Vol.20 No.3

Among the various types of congenital meniscal anomalies, the double-layered lateral meniscus is extremely rare. The double-layered meniscus consists of both the upper additional and the lower normal meniscus. As the upper additional meniscus is mobile, it can be easily displaced, while the lower lateral meniscus is usually normal in shape and volume. A 42-year-old woman suffering from pain and locking of her left knee underwent Magnetic resonance imaging (MRI) examination and an arthroscopic surgery. A rare meniscal abnormality was seen in her left knee, which presented as a double-layered lateral meniscus with displacement. It was remarkable that the upper additional meniscus was displaced over the intercondylar eminence of the tibia and it mimicked a bucket-handle tear. Even though it is rare, it is necessary to consider the possibility of displaced double-layered meniscus in the differential diagnosis of a bucket-handle tear. Here, we report the MRI and arthroscopic findings of a displaced double-layered lateral meniscus, which was similar to the bucket-handle tear.

Radiological Features of a Fibro-Osseous Pseudotumor in the Digit: A Case Report

곽민지,김선기,이상욱,전선영,이안희 대한영상의학회 2015 대한영상의학회지 Vol.73 No.2

A fibro-osseous pseudotumor is a rare ossifying soft tissue lesion, which is thought to be a reactive rather than a neoplastic lesion, developing due to repeated trauma. The lesion mostly occurs in the subcutaneous tissue of the proximal phalanx of the digit and predominantly affects young adults, with a slight predominance in females. The clinicopathological features can mimic those of malignant soft tissue lesions, and diagnosis can be difficult. Less is known about the radiological appearance of the lesion, including magnetic resonance imaging (MRI) features, than about histological signs. Here, we report radiological findings, including MRI features, of a fibro-osseous pseudotumor of the digit in a young female.

National Trends in Smoking Cessation Medication Prescriptions for Smokers With Chronic Obstructive Pulmonary Disease in the United States, 2007-2012

곽민지,김종오,Viraj Bhise,Tong Han Chung,Gabriela Sanchez Petitto 대한예방의학회 2018 Journal of Preventive Medicine and Public Health Vol.51 No.5

Objectives: Smoking cessation decreases morbidity and mortality due to chronic obstructive pulmonary disease (COPD). Pharmacotherapy for smoking cessation is highly effective. However, the optimal prescription rate of smoking cessation medications among smokers with COPD has not been systemically studied. The purpose of this study was to estimate the national prescription rates of smoking cessation medications among smokers with COPD and to examine any disparities therein. Methods: We conducted a retrospective study using National Ambulatory Medical Care Survey data from 2007 to 2012. We estimated the national prescription rate for any smoking cessation medication (varenicline, bupropion, and nicotine replacement therapy) each year. Multiple survey logistic regression was performed to characterize the effects of demographic variables and comorbidities on prescriptions. Results: The average prescription rate of any smoking cessation medication over 5 years was 3.64%. The prescription rate declined each year, except for a slight increase in 2012: 9.91% in 2007, 4.47% in 2008, 2.42% in 2009, 1.88% in 2010, 1.46% in 2011, and 3.67% in 2012. Hispanic race and depression were associated with higher prescription rates (odds ratio [OR], 5.15; 95% confidence interval [CI], 1.59 to 16.67 and OR, 2.64; 95% CI, 1.26 to 5.51, respectively). There were no significant differences according to insurance, location of the physician, or other comorbidities. The high OR among Hispanic population and those with depression was driven by the high prescription rate of bupropion. Conclusions: The prescription rate of smoking cessation medications among smokers with COPD remained low throughout the study period. Further studies are necessary to identify barriers and to develop strategies to overcome them.

경산지역 PM<SUB>2.5</SUB> 측정 및 농도 특성에 관한 연구

곽민지,서경현,장명기,김경민,황인조 한국대기환경학회 2015 한국대기환경학회 학술대회논문집 Vol.2015 No.11