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한정현 ( Jung Hyun Han ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7
Background: Lupus miliaris disseminatus faciei (LMDF) is a rare granulomatous disease characterized by eruption of discrete red-brown, dome-shaped papules, predominantly in the lower eyelid. Histopathologically, LMDF could present as caseous necrosis in the central area with granulomas composed of epithelioid cells and giant cells. The pathogenesis of LMDF remains controversial. Some suspect LMDF as a kind of cutanoeus tuberculosis, but others believe LMDF to be a variant of granulomatous rosacea or sarcoidosis. Objective: This study aimed to investigate the clinical and histopathologic features of LMDF. Methods: We reviewed the medical records, clinical photographs, and histopathologic slides of 30 cases of LMDF that were evaluated in our department between February 1991 and May 2009. Results: The average age of the affected patient was 34.6±10.9 years and the ratio of male-to-female patients was 3.3:1. The most common sites of involvement with LMDF was the eyelid (86.7%). cheek (76.7%), philtrum (60.0%), and glabella (56.7%). On histopathologic examination, the epithelioid granulomas had a connection to pilosebaceous structures in 66.7% of the cases. Follicular rupture (33.3%), perifollicular granulomas composed of naked tubercles (53.2%), and sarcoidal granulomas with abscesses (23.3%) were noted. Characteristic caseous necrosis occurred in 7 cases (23.3%). The duration of LMDF was 2 years in 26 cases (86.7%) and the lesion improved leaving scar in 21 cases (70%). Conclusion: We identified the histopathologic changes of LMDF as a function of disease duration. Connections of pilosebaceous units with granulomas were commonly observed. It will be helpful to understand the pathophysiology of LMDF.
한정현 ( Jung Hyun Han ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.6
Extramammary Paget`s disease (EMPD) is an unusual neoplasm that affects apocrine gland-bearing skin, such as the vulva, perianal region, scrotum, and penis. However, EMPD has been rarely observed in the non-apocrine, gland-bearing regions; such cases are referred to as ectopic EMPD. We present a case involving a 46-year-old man in whom ectopic EMPD affected the scalp. Although the clinical appearance was suggestive of pagetoid Bowen`s disease, EMPD was confirmed by biopsy and immunohistochemical studies. In Korea, there has been only one report of EMPD occurring in the scalp. EMPD of the scalp is extremely rare, with few reported cases. We report a case EMPD of the scalp with a review of the literature. (Korean J Dermatol 2011;49(6):550∼553)
한정현 ( Jung Hyun Han ),윤숙정 ( Sook Jung Yun ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ),이지범 ( Jee Bum Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.1
Ambulatory phlebectomy is a procedure for the removal of superficial veins through small incisions. It is commonly used to treat varicose veins in the legs. Compared with alternative procedures such as sclerotherapy and laser therapy, phlebectomy is less likely to cause conditions such as hyperpigmentation, cutaneous necrosis, superficial phlebitis and deep vein thrombosis. Phlebotomy is cosmetically effective for the removal of facial reticular veins, which are currently cosmetic issues. The first patient, a 42-year-old woman, presented with a 3 cm sized bluish linear patch on her right lower eyelid. Color-flow duplex ultrasonography confirmed that it was dilated superficial vein. The second patient, a 51-year-old woman, came to our clinic with reticular vessels on the nasal dorsum and left lower eyelid. Both patients were treated with phlebectomy and they showed a cosmetically satisfactory outcome. This paper reports on two cases of facial reticular vessels that were treated with phlebectomy and the course of the procedure. (Korean J Dermatol 2011;49(1):40~44)
韓正鉉 성신여자대학교 교육문제연구소 1994 교육연구 Vol.28 No.-
자본주의사회에 있어서 사기업의 활동원리인 경쟁은 그 자체 속에 독점의 씨앗을 간직하고 있다. 지금의 형편으로서는 독점금지법을 최대한 보완하고 또한 기업의 양심을 일께우는 일이다. 그동안 정부가 계속하여 각 대기업의 업종 전문화를 유도하여 왔지만 독과점은 여전히 심화되고 있다. 이런 문제점의 해결을 위하여 우선 30대 재벌의 업종전문화의 유도에 힘써야 하고 그것은 대기업의 사회적 책임을 일깨우는 일이다.