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두충(杜沖) 전탕액(煎湯液)이 흰쥐의 혈청(血淸) 지질(脂質) 대사(代謝)에 미치는 영향(影響)
한상환,Han, Sang-Hwan 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.3
The effects of 3% Cortex Eucommiae extracts on serum lipid contents were evaluated in rats. Forty-two male Sprague-Dawley rats weighing $100{\pm}10g$ were divided into seven groups and fed different fat diets for four weeks. Each group was administered with following group: Control, basal fat diet, saturated fat diet and unsaturated fat diet respectively was fed 1% cholesterol, Cortex Eucommiae extracts 3%. The contents of serum lipid contents triglyceride in the basal fat diet group were higher than those of control group. The contents of total-cholesterol in serum of the saturated fat diet group was significantly higher than other group. The contents of HDL-cholesterol in serum of the 3% Cortex Eucommiae extract group were higher than those other fat diet group. The contents of LDL-cholesterol in serum of the 3% Cortex Eucommiae ex1ract group was lower than other fat diet groups. These results suggest that 3% Cortex Eucommiae extract group may reduced elevated levels of serum lipid contents in rats different fed fat diet.
오미자(五味子) 전탕액(煎湯液)의 투여(投與)가 흰쥐의 혈청(血淸) cholesterol 대사(代射)에 미치는 영향(影響)
한상환,Han, Sang-Hwan 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.1
It was investigated effect of Fructure schizandra chinesis Water extract on the white rat which was induced hypercholesterolemia by fatty diet. The results obtained were summarized as follows; Neutral lipid level in blood lipid was greatly decreased on the group being fed animal fat diet and Fructure schizandra chinesis Water extract, total cholesterol was decreased on the group being fed vegetative fat diet, HDL-cholesterol was shown that the group being fed vegetative fat diet and Fructure schizandra chinesis Water extract at a time more increased HDL-cholesterol in a little than the other group, and normal fat diet group show to highest figure,38.5mg/dl. Animal fat diet group is 20.75 mg/dl. but, the group being fed Fructure schizandra chinesis Water extract was increased to 31.00mg/dl. LDL-cholesterol had no difference between fat diet group and the group being fed Fructure schizandra chinesis Water extract.
유한요소 해석을 이용한 WUF-W 접합부 최적의 파단 예측 반응지표 선정
한상환,김영우,김태오,Han, Sang Whan,Kim, Young Woo,Kim, Tae O 한국지진공학회 2017 한국지진공학회논문집 Vol.21 No.5
The WUF-W moment connection is a pre-qualified connection that can be used for special moment frames specified in current seismic design specifications. Since the stress distribution near the connection varies according to access hole configuration, the cyclic performance of WUF-W connections is strongly affected by the access hole configurations. To evaluate the connection performance according to various access hole configurations, it is expensive to conduct experiments with many connection specimens. Instead, finite element analyses (FEA) can be performed. Throughout the FEA, stress and strain distribution in the connection can be monitored at each loading step. The purpose of this study is to construct nonlinear 3-dimensional FE models for accurately predicting the cyclic behavior of WUF-W connections. For predicting connection fracture using FEA, an appropriate response index detecting the incidence of connection rupture is proposed.
목표스펙트럼에 근사한 평균응답스펙트럼을 갖는 지반운동집단의 효율적인 선정방법
한상환,석승욱 한국지진공학회 2011 한국지진공학회논문집 Vol.15 No.5
본 연구에서는 지반운동 라이브러리에서 목표스펙트럼에 근사한 평균응답스펙트럼을 갖는 한 개 혹은 다수의 지반운동을 선정하는 효율적인 방법을 제안하고자 한다. 지반운동 선정 시 목표스펙트럼의 형상과 크기를 맞추어야 하는데 이 두 가지를 독립적으로 고려할 수 있다는 기존 연구결과에 따라 본 연구에서도 형상이 가장 유사한 지반운동을 찾고 크기를 맞추기 위하여 배율조정계수를 사용한다. 형상을 맞추기 위해 각 주기에서 목표스펙트럼과 지반운동 평균응답스펙트럼의 차이 값의 표준편차가 최소가 되도록 하여 선정하는 방법을 제안하였다. 형상이 결정된 후 그 크기를 맞추기 위해 본 연구에서 제안한 배율조정계수를 찾는 방법은 기존 연구와 달리 한번에 찾을 수 있도록 제안하였다. 40개의 지반운동 라이브러리로부터 제안한 방법을 이용하여 목표스펙트럼에 근사한 평균스펙트럼을 갖는 7개의 지반운동기록을 선정한 결과, 그 정확성과 계산소요시간에 있어 모두 만족할만한 결과를 보였다. This paper proposes an efficient method for selecting ground motions with the mean response spectrum matching a target spectrum. Since former studies reported that the shape and amplitude of the response spectra can be treated independently for selecting ground motions, this study first selects ground motions such that the shape of their mean response spectrum matches that of the target spectrum, then scales the ground motions. To select the ground motions best matching the shape of the target response spectrum, the standard deviation of the difference between the target response spectrum and the mean response spectrum of the selected ground motions needs to be minimized. Unlike the existing procedure, the scaling factor can be computed without iteration. Based on the selection results of 7 ground motions from a library of 40 ground motions, the proposed method is verified as an accurate and efficient method.
WUF-W 접합부의 액세스 홀 형상변수 타당성 평가를 위한 경험식 제안
한상환,윤용,Han, Sang Whan,Yoon, Yong,Kim, Y. Debbie 한국강구조학회 2017 韓國鋼構造學會 論文集 Vol.29 No.4
WUF-W 접합부는 부재의 접합이 모두 용접으로 이루어진 접합부이며, 특수모멘트골조(SMF) 인증접합부 중 하나이다. 하지만 선행 연구들을 통해 일부 WUF-W 접합부 실험체가 4% 층간변위비의 특수모멘트골조(SMF) 요구성능을 만족하지 못하였으며, 이는 액세스 홀 형상과 연관이 있음이 보고되었다. 본 연구에서는 비선형 유한요소 해석을 이용하여 WUF-W 접합부의 요구성능을 만족하기 위한 주요 액세스홀 형상변수의 허용범위를 결정하였다. 또한 WUF-W 접합부 설계과정에서 주요 액세스 홀 형상변수의 타당성을 평가할 수 있는 간단한 경험식을 제안하였다. The welded unreinforced flange-welded web(WUF-W) connection is an all-welded moment connection, which is qualified for special moment frame(SMF) connections. However, previous studies reported that some WUF-W connections did not meet the drift requirement specified for SMF connections and such unexpected connection performance was resulted from weld access hole geometry. The objective of this study is to determine the permissible ranges of major access hole parameters such as access hole slope and the length of flat portion that lead to the satisfactory performance of WUF-W connections using Nonlinear finite element analyses are conducted. This study also proposes simple empirical equations to check the validity of access hole parameters to be selected in design process.
가스크로마토그래피를 이용한 요중 마뇨산 측정시 새로운 시료 전처리 방법의 검증
조수현,임용현,김선민,권호장,하미나,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1
Urinary hippuric acid was analyzed by gas chromatography/mass spectrometry method. A simple and economical derivatization procedure using excessive methanol in acidic condition was adopted to esterify hippuric acid. Quantitative analysis was performed with two internal standards, heptadecanoic acid and hydrocinnamic acid, to evaluate the derivatization procedure as an analytical method. Using the standard addition method, linear and reproducible calibration curves were obtained for both internal standards. Calibration experiment showed that good quantitative result could also be obtained with the calibration curve obtained without urine matrix. Recovery rates for the urine samples were in the range of 95.6∼111.4%. Using hydrocinnamic acid as internal standard, analysis time could be reduced.
조수헌,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1
The case was described of a 43 year old male who developed burns of the both shins as a result of handling wet cement. After wet cement was spilled into the rubber boots he was wearing, he experienced painful erythema of both lower legs. Several weeks later, medical examination revealed dirty and granulated ulceration of the both shins. The largest ulcer, about 18 by 10 centimeters, was located on the anterior aspect of left lower leg. We concluded that this skin problem resulted from the extreme alkalinity of calcium hydroxide in wet cement, combined with the effects of pressure and occlusion against the skin.