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結核性 肺肋膜 疾患의 肺臟機能에 關한 硏究 : 第五編 肺內 GAS 分布에 關하여 Ⅴ. On Intrapulmonary Mixing of Gas
朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1
Index of intrapulmonary mixing was determined by Cournand's open circuit method on 147 patients with tuberculous pleuro-pulmonary diseases and the result was compared with that of normal control. The mean values of 20 healthy Korean males and 20 females were 1.61% and 1.55%, respectively, the highest value obtained being 2.30%. The results obtained from various groups of patients were uniformly higher than those of healthy subjects, However, index of intrapulmonary mixing showed no close correlation with the extent of disease process and severity of dyspnea.
朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1
A study was carried out to evaluate the clinical and pathophysiological significance of oxygen consumption and ventilation equivalent in tuberculous pleuro-pulmonary diseases based on an analysis of 225 cases in lying and sitting position, and during exercise. Oxygen consumption in lying and sitting position showed no significant difference, regardless of type and extent of disease process, and degree of dyspnea on exertion, from that of normal value. During exercise, however, a marked decrease was noted in patients, particularly in those with moderately to far advanced pulmonary tuberculosis, pleurisy, and with dyspnea on slight exertion. Ventilation equivalent showed marked individual variation but the mean values in lying and sitting position were about the same as those of normal, without close correlation to extent and type of disease process, and degree of dyspnea on exertion. However, it was higher than normal during exercise, particularly in those with far advanced pulmonary tuberculosis, pleurisy, and with dyspnea on slight exertion, probably as a result of decreased oxygen uptake in these groaps of patients. The fact that oxygen consumption and ventilation equivalent showed significant difference from those of normal only during exercise is probably due to impaired functional reserve of the lung, which emphasizes the importance of exercise test for the evaluation of pulmonary function.
朴熙明,Herrmann, George R.,Hejtmancik, Milton R. 慶北大學校 醫科大學 1959 慶北醫大誌 Vol.2 No.1
Ten years have elapsed since a study of paroxysmal ventricular tachycardia (PVT) was made at the University of Texas Medical Branch Hospitals. In this decade more effective and accurate diagnostic criteria have been established by improvements in electrocardiography. In addition, new antiarrhythmic and supportive agents have become available. The present analysis includes 83 episodes of PVT in 59 patients treated since the previous publication. There were 38 persistent and 45 intermittent episodes. Although the youngest patient was 9 months of age and thd oldest 97 years, 80% of the patients were between the 5th and 7th decades. There were 33 males and 26 females. Rate of the tachycardia varied from 104 to 231, and the duration varied from a few seconds to over 7 days. Electrocardiograms before and after the paroxysms were available in 40 and 42 of 59 patients, respectively. In about 30% atrial fibrillation was recorded before and after the PVT. Coronary artery disease with or without hypertension was present in 42 case (71%), and 13 of these had acute myocardial infarction. Rheumatic heart disease occurred in 7 patients (12%). Six patients (10%) had no organic heart disease. Digitalis had been given to 32 patients (54%), and in 16 of these there was digitalis intoxcation. Congestive heart failure was precipitated or aggravated by the PVT in 60% of the patients. Dyspnea and weakness were the most frequent symptoms, but there were often chest pain and palpitation, and occasionally cerebral manifestations. In about 30% of the persistent cases, the blood pressure had to be maintained with vasopressor agents. The effectiveness of quinidine therapy was confirmed. However, many PVT episodes reverted upon administration of procaine amide, which appeared the most effective intravenous preparation. Potassium therepy was a valuable adjunct in the cases due to digitalis overdosage. Combinations of drugs were occasionally necessary in refractory cases. Newer drugs, such as chloroquin offers promise, and deserve more extensive trial. Although most of episodes responded well to therapy, the long term prognosis was poor, as 31 of these patients (54%) died within 10 months after the onset of ventricular tachycardia The mortality rate was even higher (77%) in the patients in whom PVT complicated acute myocardial infarction.
結核性 肺肋膜 疾患의 肺臟機能에 關한 硏究 : 第三編 AIR TRAPPING에 關하여 Ⅲ. On air Trapping
朴熙明 慶北大學校 醫科大學 1961 慶北醫大誌 Vol.3 No.1
Timed vital capacity, air trapping index, Leslie's index, air velocity index and capacity ratio were determined on 225 cases with tuberculous pleuro-pulmonary diseases. In addition, timed vital capacity, air velocity index and capacity ratio were measured on 141 normal Koreans, and Leslie's index and air trapping index were determined on 40 healthy Koreans for the establishment of normal standards of these tests. The mean values of the first, second and third second timed vital capacity showed no significant difference from those of healthy Americans. However, the first second timed vital capacity showed marked individual variations in the normal as well as in the diseased, making the evaluation of this value unreliable and unsuitable. In patients with pulmonary tuberculosis, the second and third second vital capacity was generally decreased, and it was particulaly true in patients with far advanced pulmonary lesions or severe dyspnea on exertion. Air trapping index and Leslie's index also showed marked individual variations suggesting that these tests cannot be of great help for the individual case analysis in a patient with suspected pulmonary insufficiency. However, it was noted that abnormally increased air trapping index and Leslie's index were more frequently found in patients with advanced pulmonary lesions or marked dyspnea. Air velocity index and capacity ration in normal Koreans were essentially similar to those of Americans, and mean values of these two tests in various groups of patients were all within normal limits, However, abnormal data were more frequently found in patients with advanced pulmonary lesions, pleural involvement and marked dyspnea on exertion. Decreased air velocity index and capacity ratio were resulted from decrease in maximal breathing capacity in most cases and from decrease in both maximal breathing capacity and vital capacity in some.
중국산 샤페이 개에서 발생한 림프구성-형질구성 장염의 발생예
박희명,오태호,황철용,한홍율,윤순식 한국임상수의학회 1998 한국임상수의학회지 Vol.15 No.1
A two-year-old male Chinese Shar poi dog was admitted to the hospital because of chronic diarrhea. Abnormalities detected on physical examination were thickened intestinal loops and thin or cachexic body condition.4 complete blood count revealed a mild neutrophilia. The blood chemistry panel indicated no significant abnormalities. On proctoscopic examinations colonic mucosa was reddened and edematous. Numerous Iymphocytes, plasma cells and epithelial cells were observed in the cytologic examination of the rectal scraping.4 treatment was initiated with sulfasalazinei metronidazole and prednisolone and dietary management with rice and cottage cheese was performed simultaneously. Although antibiotic therapy and dietary management were donee the dog's condition deteriorated and died suddenly. Lymphocytic-plasmacytic enterocolitis was diagnosed by postmortem pathologic examination.