희토류원소에 의한 탈황 및 개재물 형태변화에 관한 연구

박종우,문인기,송규섭 대한금속재료학회(대한금속학회) 1983 대한금속·재료학회지 Vol.21 No.4

Together with the deoxidation and desulphurizaton behaviors of RE (rare earth element) treated molten steel, the changes in shape, size, and constitution of the RE inclusions after RE treatment were studied in 0.3%C-1.3%Mn-0.02%S steel using high frequency induction furnace with magnesia crucible. It was found that little additional deoxidation occurred when RE addition was made to the molten steel pre-deoxidized with 0.05% Al, whilst considerable desulphurization was observed. The effectiveness of desulphurization increased with the amount of RE added. It is believed that the desulphurization occurred mainly by the formation of RE-sulphide rather than RE-oxysulphide and the growth of RE-sulphide was accelerated by the induction stirring. During holding after RE treatment, resulphurization and fading of globular RE-inclusions, accompanied by the formation of MnS, occurred possibly due to the reoxidation of the molten steel.

Phenylpropanolamine 음독 후 발생한 심근허혈

박종우,좌민홍,박준석,조광현,Park Jong Woo,Choa Min Hong,Park Joon Seok,Cho Kwang Hyun 대한임상독성학회 2003 대한임상독성학회지 Vol.1 No.1

Phenypropanolamine (PPA) is a sympathetic amine used in over-the-counter cold remedies and weight-control preparations. The side effects are hypertension, dysrhythmias, stroke, etc. The Food and Drug Administration (FDA) is taking steps to remove PPA from all drug products and has requested that all drug companies discontinue marketing products containg PPA due to high risk of hemorrhage stroke. But, in Korea now, patinets take products containg PPA with over the counter. We report here the case of PPA induced myocardial injury in a young woman who takes overdose for suicide.

Targeting epigenetics for cancer therapy

박종우,Jeung-Whan Han 대한약학회 2019 Archives of Pharmacal Research Vol.42 No.2

Cancer can be identified as a chaotic cell state, which breaks the rules that govern growth and reproduction, with main characteristics such as uncontrolled division, invading other tissues, usurping resources, and eventually killing its host. It was once believed that cancer is caused by a progressive series of genetic aberrations, and certain mutations of genes, including oncogenes and tumor suppressor genes, have been identified as the cause of cancer. However, piling evidence suggests that epigenetic modifications working in concert with genetic mechanisms to regulate transcriptional activity are dysregulated in many diseases, including cancer. Cancer epigenetics explain a wide range of heritable changes in gene expression, which do not come from any alteration in DNA sequences. Aberrant DNA methylation, histone modifications, and expression of long non-coding RNAs (lncRNAs) are key epigenetic mechanisms associated with tumor initiation, cancer progression, and metastasis. Within the past decade, cancer epigenetics have enabled us to develop novel biomarkers and therapeutic target for many types of cancers. In this review, we will summarize the major epigenetic changes involved in cancer biology along with clinical and preclinical results developed as novel cancer therapeutics.

玉山書院 소장 조선간본 『夢溪筆談』의 간행과 서지학적 가치

박종우,민관동 고전문학한문학연구학회 2018 고전과 해석 Vol.26 No.-

The paper is based on a Joseon edition of "Monggye-pil-dam(夢溪筆談)". This book was a rare early edition and there was an important bibliographic value. So we researched that what was about historical meaning and bibliographic information of the book. It was confirmed that the edition was published in approximately 1478-1479 [‘Sungjong(成宗)’ 10] in “Gyeongju(慶州)”. The publisher of the Joseon edition was “Kang Hee-meng(姜希孟)”. The publication of the book was initiated by the personal interest of his father “Kang Suk-Duk(姜碩德)”. The historical meaning of this book's publication has been divided into three parts. First of all, it was the first domestic version. Second, the advanced academic and cultural studies and culture of “Song(宋)” Dynasty, had been introduced and expanded in Joseon. The third is that similar forms of encyclopedic writing were sparked. The bibliographic value of this book's publication also has been divided into three parts. First, it is the first Korean edition for of "Monggye-pil-dam(夢溪筆談)". Second, as the literature material of the first half of the 15th century, it is a well-preserved edition. Third, the books of the Joseon Dynasty's local publication can be fully identified. Rare copies of Chinese classical texts published in Joseon have been discovered and reported to the academic community. Therefore, it seems very urgent to continue to investigate and research about that. 이 논문은 옥산서원 소장 조선간본 『몽계필담』을 대상으로 하여 간행 경위, 역사적 의미, 서지학적 가치에 대해 살펴본 것이다. 조선간본 『몽계필담』 하책의 끝부분에 姜希孟의 「跋文」이 있고 작성시기가 기록되어 있어서, 대략 1478∼1479년(성종 10)에 간행된 판본임을 확인하였다. 그리고 상책의 1면 우측 여백에 藏書記가 있어서 경주 옥산서원에 수장된 시기가 1573년임을 밝혔다. 『몽계필담』 간행은 姜希孟의 발문에 따르면 부친 姜碩德에 의해 시작된 것이었다. 부친이 우연히 궁중 서고에서 『몽계필담』을 보았고, 내용이 좋아 필사하여 집안에 소장하였다. 이어 출간을 하려고 했지만 오류가 많아 간행에는 이르지 못했다. 이후 친지가 강희맹에게 중국본 한 질을 갖고 와서 다시 간행 작업을 진행하였고, 친분이 있던 鄭孝常이 경상도관찰사로 부임하자 부탁하여 慶州府에서 간행하게 되었다. 조선간본 『몽계필담』의 간행이 가지는 역사적 의미는, 첫째 최초의 국내 유통본이라는 점이다. 두 번째는 중국 송대의 선진 학술과 문화가 국내에 도입‧확산되었다는 점이다. 세 번째는 유사한 형태의 백과사전식 저술이 촉발되는 계기가 되었다는 점이다. 서지학적 가치로는 첫째 『몽계필담』의 최초의 국내 간본이라는 점이다. 둘째 15세기 전반의 문헌으로서 보존 상태가 양호한 완질의 판본이라는 점이다. 셋째 조선 전기 지방 간본 문헌의 서지와 형태를 온전히 확인할 수 있는 자료라는 점이다.

1960년대 후반 1970년대 초반 서울의 구릉지 저소득층 공동주택에 관한 연구

박종우,이상준,장림종,최성환,양영준,하종효 대한건축학회 2005 대한건축학회논문집 Vol.21 No.12

The study is about an affordable housing, located on hillside, in the aspect of housing policies. It includes Sky apartment housing and Si-min apartments. After the Korean War, Seoul suffered from serious shortage of housing because of the destruction during the war and people's immigration from the country to the city. According to the urbanization, poor people illegally occupied public land, especially hillside area. The wide urban area turned out to shanty town. The government employed an extreme policy focusing on demolition and dislocation of people until 1972. During the last four years of the period, improved policies appeared. On the other hand the study will take three housing cases constructed between the late 1960s and the early 1970s for the closer examination. They are Jeogneung Sky Apartment, Si-Min Apartment, and Yeoido Si-Beom Apartment. As a result the study shows a positive public aspect of housing development in late 1960s through early 1970s.

변압기의 유지관리

박종우 한국조명전기설비학회 1995 조명.전기설비 Vol.9 No.3

DRAM반도체 소자의 최근 기술동향

박종우 한국전기전자재료학회 1994 電氣電子材料學會誌 Vol.7 No.2

DRAM(Dynamic Random Access Memory)은 반도체 소자중 가장 대표적인 기억소자로, switch역활을 하는 1개의 transistor와 data의 전하를 축적하는 1개의 capacitor로 구성된 단순한 구조와 고집적화에 용이하다는 이점을 바탕으로, supercomputer에서 가전제품 및 산업기기에 이르기 까지 널리 이용되어왔다. 한편으로 DRAM사업은 고가의 장치사업으로 조기시장 진입을 위하여 초기에 막대한 자본투자, 급속한 기술발전, 짧은 life cycle, 가격급락등이 심하여, 시한내 투자회수가 이루어져야 하는 위험도가 큰 기회사업이라는 양면성도 가지고 있다. 이러한 관점때문에 새로운 DRAM기술은 매 세대마다 끊임없이 빠른 속도로 개발되어왔다. 그러나 sub-micron이하의 DRAM세대로 갈수록 그에 대한 신기술은 점차 어렵게 되어가고, 한편으로는 system의 다양화에 따른 요구도 강하여, 이제는 통상적인 DRAM의 고집적화/저가의 전략만으로는 생존하기 어려운 실정이므로 개발전략도 수정하여야만 할 것이다. 이러한 어려운 기술한계를 극복하기 위하여 새로운 소자기술 및 공정개발에 대한 breakthrough가 이루어져야 할 것이다. 이러한 관점에서 현재까지의 DRAM개발 추이와 향후의 기술방향에 관하여 몇가지 중요한 item을 설정하여 논의해 보기로 한다.

파열현상이 충격인성 및 천이온도에 미치는 영향

박종우,문인기,김정석 대한금속재료학회(대한금속학회) 1984 대한금속·재료학회지 Vol.22 No.1

Delamination mode and effect of delamination on the impact toughness and transition temperature were studied in (i) conventionally rolled carbon steels with considerable amount of elongated MnS inclusions, and (ii) controlled rolled HSLA steels with only small amount of S and globular sulphide inclusions. The observed phenomena were explained in terms of delamination mechanism, stress state and distribution, stress pulse duration, and fracture energy.

고도 정수처리 공정에 의한 수중의 농약 제거

박종우,장성일,김장억 한국농약과학회 2000 한국농약과학회 학술발표대회 논문집 Vol.- No.-

특집: 당뇨병과 안과질환 -당뇨망막병증 인터뷰 -"증상 없더라도 정기검진 꼭 받으세요"

박종우,Park, Jong-U 사단법인 한국당뇨협회 2011 당뇨 Vol.255 No.-