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      • KCI등재

        The Effects of Patient Safety Culture Perception and Safety Control on the Patient Safety Management Activities of Psychiatric Ward Nurses

        박대규,안효자 한국정신간호학회 2023 정신간호학회지 Vol.32 No.2

        Purpose: To provide basic data to find ways to increase the patient safety management activities of psychiatric ward nurses and establish measures for patient safety. Methods: The research was conducted with psychiatric nurses who had worked for > 6 months in 9 psychiatric hospitals across 3 regions. Data collection spanned June 16 to July 7, 2022, the research tools being patient safety culture perception, safety control, and patient safety nursing activities. Results: A hierarchical regression analysis showed the factors influencing patient safety management activities. In Model 1, factors of the position of the subject and number of accident reports in the past year appeared significant (F=6.63, p<.001); the explanatory power was 9.8 %. In Model 2, patient safety culture perception appeared significant (F=15.26, p<.001); explanatory power increased to 45.1 %. In Model 3, safety control appeared significant (F=14.63, p<.001); explanatory power increased to 46.6 %. Among the perceptions of patient safety culture, communication, and procedures, incident-reporting frequency and hospital environment were identified as significant. Conclusion: The factors for psychiatric nurses' patient safety management activities are patient safety culture perception and safety control. Patient safety culture perception is a particularly important factor, and a strategy is needed to increase it.

      • 배양중인 계배간충직세포의 protein kinase C 활성도 분석

        朴大圭,孫鍾京,鄭在昌 경북대학교 1992 논문집 Vol.24 No.-

        To investigate the relationship between protein kinse C (PKC) and chondrogenesis, PKC activity was assayed in cultures of stage 23/24 chick limb bud mesenchymal cells under various conditions. PKC activities of cytosolic and particulate fractions were low in 1 day cultured cells. As chondrogenesis proceeds, cytosolic PKC activity increased more than 2-fold, while that of the particulate fraction increased only slightly. Three days' treatment of cultures with PMA(5×10 exp (-8)M) inhibited chondrogenesis judged by the accumlation of Alcian blue bound to the extracellular matrix and depressed PKC activity in cytosolic fraction. When cells were grown for 3 days in control medium after 3 days' treatment with PMA, chondrogenesis resumed and PKC activity recovered to normal values. PKC activity in cultures plated at low density (5×10 exp (6) cells/ml) or that in PMA treated cells. On the other hand, staurosporine promoted chondrgenesis without affecting PKC activity. Furthermore, reversal of PMA's inhibitory effect on chondrogenesis by staurosporine was not accompanied by recovery of PKC activity. These data indicate that increases in PKC activity is closely related to chondrogenesis and that PMA inhibits chondrogenesis by depressing PKC. However, staurosporine's enchancing effect of chondrogenesis is not related of PKC activity.

      • 조직의 분권화시스템에 있어서의 의사결정과 회계정보전달에 관한 효과분석

        朴大圭 尙志大學校 産業經營硏究所 1997 産業經營硏究 Vol.6 No.-

        This paper is to analyze the effectiveness of organizational decentralization and centralization in conveying the accounting information for the decision-making. The large-scale of business size and the environment's complexity need the decentralized enterprise. Additionally, this is based upon the report system of departmental performance, evaluations and accounting information. In case of decentralized organization, as for the characteristics of specialized department, and in considering the reality of each department providing only local information, this central headquarters has the necessity to receive the exact report for the sake of rationale on decision-making from a whole members of the department. However, department manager will have the possibility to report private information which may be invalid to the department's interest. This decision-making based on incorrect information will not be the optimum alternative. I think that the development of an evaluation of the performance will be required as for the incentive system that has characteristics to report only a true information. The introduction of evaluation from performance make department managers to report a departmental information exactly as the incentive system. This system induces to be reported with a true information voluntarily. It is because of unexpceting benefits through false reports from each department for central headquarters that manager establishes rational plan in accordance with above contents and will set up optimum decision-making by establishing a budget. Like this, central managers have to device proper incentive compensation systems which make department managers to induce optimum decision-making for the benefits of the enterprise. This is in the case of imbalance intelligence. information reporting system must be established in order to have smooth communication. Departmental decision that do not cause problems like morale hazards if all the necessary information reported completely as a matter of fact. Therefore, is it a valuable concept that departmental decision-making is entrusted to department managers in decentralized organization which uses information reporting systems? Or is it a valuable concept that authorities of decision-making is entrusted to department managers, if there is no communication between central manager and departmental manager? These subjcets must be regarded as important in the dimension of analysis. I will study and review the characteristics of decentralization by managerial accounting, and information acquisition for communication relating to decision-making, possibility of false-information being conveyed and incentive plan for conveying a true information, especially, in the case study of the theory on which M. Loeb and W. A. Magat insists.

      • KCI등재
      • KCI등재후보

        물류시스템의 관리적 요인이 물류성과에 미치는 영향에 관한 실증적 연구

        박대규,이경복,김효선 대한경영학회 2002 大韓經營學會誌 Vol.15 No.1

        Ⅰ. 서 론기업의 원가절감은 생산의 상류에 해당하는 기획 , 또는 연구개발 단계에서부터 원가를 관리해 나가는 방법과 하류에 해당하는 물류비를 합리적으로 관리하는 방법으로 전환하고 있다. 17% 를 차지하여, 미국의 7.5%와 일본의 11.3%를 비교하여 물류비 부담이 과중하다 . 또한 최근에는 매년 19% 씩 물류비가 상승하고 있다는 통계도 나와 있다 . 쟁력에 직결되므로 물류면의 우위를 확보하는 것이 기업의 사활을 좌우하는 문제로 대두되고 있다.이러한 관점에서 물류시스템이 효과적으로 관리되고 , 경쟁력을 갖추기 위해서는 최적화

      • 계배 발생에 따른 닭 alpha-Fetoprotein의 분석

        박대규,유정아 한국통합생물학회 1989 동물학회지 Vol.32 No.4

        배의 발생과 분화에 따른 혈청 alpha-fetoprotein (AFP)의 생리적 기능 규명을 위한 기초실험의 일환으로, 모체와는 완전히 독립된 상태에서 발생과 분화가 이루어지는 계배의 혈청을 재료로 하여 CM-Sephadex C-50, hydroxyapatite 및 DEAE-Sepharose A-25등의 크로마토그라피 방법에 의해 닭 혈청 AFP를 분리하였다. 계 AFP는 분자량이 약 60 Kd로 사람 및 다른 포유동물 AFP의 분자량 (64-74 Kd)보다 작았다. 닭 AFP, 계배혈청 및 닭 혈청 등을 토끼에 면역하여 항체를 제조하였고, 이를 이용하여 닭의 배발생 단계에 따른 혈청 AFP 함량의 변화를 전기영동 및 면역학적 방법으로 정성 및 정량 분석을 실시하였다. 혈청 AFP 함량은 발생 7일-배 (AFP 농도 : 0.81 mg/ml)부터 점차 증가하여 13일-배에서 최고치인 2.46 mgfml로 나타났으며 그 이후 급격히 감소되어 부화 직후에는 매우 낮은 농도 (0.22mg/ml)였고 부화 4일에 거의 없어 졌으며, 이와 같은 AFP 함량의 변화는 혈청 알부민 함량의 변화와 거의 반비례 함을 알았다. For the preliminary step to investigate the site of AFP synthesis, the ontogenic characteristics and the physiological function of AFP, alpha-fetoprotein was isolated from chick embryo serum through the procedures of CM-Sephadex C-50, hvdroxvapatite and DEAE-Sephadex A-50 chro-matography. The isolated AFP was proved to be pure and its molecular weight was found to be about 60 Kd. With this purified AFP, rabbit anti-chick hor was produced. The serum AFP level in chick embryo has been investagated by using polyacrylamide gel electrophoresis, immunoelec-trophoresis and single radial immunodiffusion from 7 days of incubation until 4 days after hatch-ing. It was found that the AFP level is increased from 0.81 mg/ml at daw-7 embryo to maximum value of 2.46 mg/ml at day-13 embryo, followed by rapid decreases until hatching.

      • Methorexate에 依한 鷄胚의 前肢 및 後肢成長에 미치는 影響

        朴大圭 慶北大學校 1975 論文集 Vol.20 No.-

        An antagonist of folic acid, methotrexate, given in a single dose of 3㎍/50㎕ distilled water to chick embryos on day 4 (stage 24) of incubation, resulted in micromelia as diagnosed by atrophyed apical portion in 60% of embryos at day 6 (stage 28). Histological studies show that the ectoderm basal lamina and the underlying mesoderm at day 6 came into being gap as a result of necrosis of mesenchyme cells. The ectoderm of the apical portion at day 8 (stage 34) shows extensive necrosis at a boundary between fore arm and digital plate, shank and toe plate. At peripheral region of the mesenchyme cells in contact with ectoderm shows pycnosis and vaculated cells by macrophages. These observation suggest that the limb malformation induced by methotrexate is brought about by inhibition of cell division to rapidly growth cell of apical portion in addition to phagocytosis of mesenchyme cells of the apical region by the macrophages.

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