腹腔渗出細胞를 移入받은 마우스에서의 肝吸蟲에 대한 免疫應答

權泰燦(Tae-Chan Kwon),姜眞無(Chin-Moo Kang),崔東翊(Dong-Wik Choi) 대한기생충학열대의학회 1987 The Korean Journal of Parasitology Vol.25 No.1

재발한 급성 혼합형 백혈병에 동반된 골수괴사 1례의 MRI 소견

박주영,박억,박샛별,전동석,이희정,김흥식,강진무,Park, Joo Young,Park, Euk,Park, Seat Byeoul,Jeon, Dong Seok,Lee, Hee Jung,Kim, Heung Sik,Kang, Chin Moo 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.2

Bone marrow necrosis is a rare complication of a variety of diseases affecting the marrow. The cause and incidence are unknown, and reports of treatment response are rare. We describe a case of relapsed acute mixed type leukemia with bone marrow necrosis. The patient was a 10 year old female diagnosed with acute mixed type leukemia four years ago. She had been on second remission state for 1 year, presented with severe back pain, tenderness in lower extremities, low-grade fever and general weakness. Her level of serum lactic dehydrogenase on admission was increased. Bone marrow aspiration from both posterior iliac crest showed marrow necrosis. Subsequent examination showed the same feature. Hip MRI showed heterogenous low signal intensity in both iliac bone on T-1 weighted image and heterogenous high signal intensity on T-2 wieghted image. Remission induction therapy was started but she expired on 59th hospital day due to the complication of sepsis.

소아 알레르기성 자반증의 위장관 내시경 소견

이동훈,박철한,박지민,박근수,김흥식,강진무,Lee, Dong Hoon,Park, Chul Han,Park, Ji Min,Park, Geun Soo,Kim, Heung Sik,Kang, Chin Moo 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.6

Purpose : This study was performed to analyze the endoscopic findings in Henoch-Schonlein purpura patients, and to compare the differences in endoscopic findings according to age and gastrointestinal symptoms. Methods : We examined children with Henoch-Schonlein purpura aged 3 to 15 years between September 1996 and October 2002. The total number studied was 65, consisting of 41 boys and 24 girls. Endoscopy was performed and the results were analysed. Results : Among 65 cases, 12 cases of duodenitis, nine cases of gastritis and duodenitis, six cases of duodenal erosion, five cases of gastritis, five cases of duodenal ulcer, two cases of gastric ulcer and one case of colonic erosion were noted. Endoscopic abnormality was found in 38 of 53 who had gastrointestinal symptoms, and in two of 12 who didn't have gastrointestinal symptoms. Conclusion : Most of the gastrointestinal symptoms in Henoch-Schonlein purpura patients were relieved without complication. But in some cases severe symptoms such as hematemesis, melena, and abdominal pain localized to epigastric area were developed when diagnosis was delayed. Prompt endoscopy will be helpful for diagnosis and therapy of Henoch-Schonlein purpura with gastrointestinal involvement.

신생아에서 Vancomycin 내성 장구균 감염 1례

배수정,최귀전,김천수,이상락,김홍식,강진무,Bae, Soo Jung,Choi, Gui Jean,Kim, Chun Soo,Lee, Sang Lak,Kim, Heung Sik,Kang, Chin Moo 대한소아감염학회 1999 Pediatric Infection and Vaccine Vol.6 No.2

Vancomycin-resistant enterococcus(VRE) was first isolated from various specimens of patients with renal failure or leukemia in 1988. Thereafter VRE has been increasing gradually and became one of the clinically important palhogenic organisms currently. We experienced a case of E. faecalis sepsis in a 4 day old neonate. She was born at 39 weeks gestational age with 2,900gm weight by Cesarean section delivery due to breech presentation. She had had swelling and motion limitation of the left knee joint with fever for one day at age of 4 day and was transfered to our hospital. Ultrasonographic examination of her left knee joint showed some inflammatory change. E. faecalis was isolated from the blood. The organism showed resistance to vancomycin on drug susceptibility test using BHI agar screening test and disk diffusion method. After treatment with ampicillin-sulbactam for 3 weeks the baby was improved. Although VRE infection has been considered rare in Korea. considerable number of demonstrative studies about VRE isolation have been reported recently thus adequate countermeasures are needed to reduce the emergence and prevent nosocomial spreading of this organism.

요추천골부 수막척수류가 동반된 전두간형 뇌류 1례

김동석 ( Dong Seok Kim ),이상락 ( Sang Lak Lee ),강진무 ( Chin Moo Kang ),김동원 ( Dong Won Kim ) 대한주산의학회 1994 Perinatology Vol.5 No.2

Changing patterns of Clonorchis sinensis infection in Kyongbuk, Korea

Chong-Yoon JOO(주종윤),Myung-Sook CHUNG(정명숙),Sun-Jin KIM(김선진),Chin-Moo KANG(강진무) 대한기생충학열대의학회 1997 The Korean Journal of Parasitology Vol.35 No.3

상부 위장관 이물에 대한 임상적 고찰 : 내시경적 진단과 적출

안성훈(Sung Hoon Ahn),허정욱(Jung Wook Hur),강영우(Young Woo Kang),이준호(Jun Ho Lee),박승국(Seoung Kook Park),박태원(Tae Won Park),강진무(Chin Moo Kang) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5

Today upper gastrointestinal (UGI) endoscopy is widely used in diagnosis and management of foreign bodies. A clinical study of 76 cases with the foreign bodies in the upper gastrointestinal tract diagnosed by flexible UGI endoscopy in Dangsan Hospital from January 1982 to December 1992 was performed. Foreign bodies were common in male (rate 1,6: 1) and in 6th decade (28 cases, 36.8%). Bezoar was the most common foreign body (57 cases, 75.0%) and foreign bodies were mostly lodged in stomach (50 cases, 65.8%). Endosopic removal or destruction was successful in 31 cases (35.4%) including all 19 cases other than bezoar. 52 cases (68.4%) hacl combined diseases, 17 cases (22.4%) had past history of operation and 9 cases (11.8%) had history nf ingestion of foreign bodies. In conclusion, UGI endoscopy and endoscopic removal is required to diagnose and manage foreign bodies in UGI tract

Alobar형 Holoprosencephaly 1례

강진무,서은숙,허상명,백태원 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.4

We experienced a case of alobar type holoprosencephaly without extracranial abnormalities except microcephaly in a 8 months old male infant. The diagnosis was made by brain CT scan, which showed the findings compatible to alobar type of holoprosencephaly. The patient is living up to the age 18 months with severe mental retardation. A brief review of literature was made.

소아 뇌종양의 임상 및 방사선 소견에 대한 고찰

조성범,김동원,강진무,우영훈,김명성,김흥식 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.4

The analysis of the clinical and radiological findings were performed on 41 cases of brain tumor in children under the age of 15 years who were admitted to Pediatric department of Dongsan Medical Center,Keimyung University, School of Medicine between May 1987 and September 1992. The clinical and rediological findings were analysed retrospectively. The results were as follows : The male to female ratio was 2.7 : 1 and the peak incidence of age was between 10 and15 years(39.0%). The supratentorial tumors were found more frequently(60.9%) than the infratentorial tumors(39.1%). Histopathologically, the astrocytoma was most common(24.4%), followed by medulloblastoma, ependymoma, craniopharyngioma. The main symptoms of the supratentorial tumors were headache(64.0%), vomiting(56.0%), nausea(44.0%),visual disturbance(32.o%), convulsion(24.0%), and endocrine dysfunction(8.0%), in order of frequency. Those of the infratentorial tumors were vomiting(87.5%), nausea(75.0%), headache(62.5%),papilledema(37.5%), ataxia(25.0%), convulsion(18.8%). The brain CT findings were different according to the histopathological findings. Most of the astrocytoma showed cystic nature, low density, and inhomogenous enhancement. Medulloblastoma was mostly located at infratentorium, and showed well enhancement and hydrocephalus in all cases. Craniopharyngioma showed suprasella hypodensed mass lesions with calcificaion in all cases. Ependymoma showed well enhancement and marked hydrocephalus in cases. 40 cases except one case of metastatic ganglioneuroblastoma had undergone complete or partial resection. Twelve patients were irradiated and 3 patients received chemotherapy after surgery. Eight patients received combind therapy with surgery, radiotherapy and chemotherapy. Out of 40 cases who received surgery, the follow up study was possible on 24 cases of which 11 cases have been alive, including 5 cases who has been survive more than 2 years.

Sydenham 무도증의 임상적 고찰

강진무,김준식,김동석 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.3

1985년 1월 부터 1992년 12월까지 계명대학교 농신의료원에 입원하여 Sydenham무도증으로 진단된 12예를 조사대상으로 선정하여 임상관찰을 하였다. 평균 연령은 14.5세, 남녀비는 3:1이었으며 Pure무도증 7예, 류마티성 무도증 5예이었고 계절별 발병빈도는 봄,가을에 많았으며 류마티일의 증상 및 괴기력이 있었던 5례에서 동반된 증상은 관절염4예, 십입 1예이었다. 진단시까지의 무도증 지속기간은 평균 1개월이었고 ASO치의 증가는 83%에서, ESR증가는 25%에서 관찰 할 수 있었으며, 뇌파 검사를 시행한 6예중 1예에서 비정상적인 Spike 소경을 보였다. 10례(85%)에서 prednisolone과 halopcridol의 병합 요법을 시행 하였으며 반응 기간은 평균3일이었으며 평균 196개월의 추적기간중 1예에서 재발이 있었다. A clinical study was carried out on twelve cases of Sydenham chorea which were hospitalized at Pediatric department of Dong San Medical Center, Keimyung University, Taegu, Korea during the period of eight years from 1985 to 1992. The following results were obtained. 1) Pure chorea without evidence of rheumatic fever was dominant(58%). 2) The age onset of chorea ranged from 11 to 19 and the mean age was 14.6 years. The male to female ratio was 3:1. 3) Sydenham chorea occurred mainly in the winter and spring(83%) 4) The duration of choreic movement before diagnosis was mostly less than 1 month. 5) They were treated with haloperidol and valproic acid(83%). The mean response time to therapy was 14.3 days. 6) The mean follow-up duration was 19.6 months and the recurrence was seen in one case. 7) No cases were expired and no neurologic sequelaes were seen.