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      • KCI등재

        Understanding the attitudes toward sunless tanning product use: implication of tanning product consumption

        JeongJu Yoo,Hyeon Jeong Cho 한국의류학회 2018 Fashion and Textiles Vol.5 No.1

        The goal of this study is to test the antecedents of overall attitudes toward sunless tanning product use. The data collected from 302 US female college students with an average age of 20.11 were included in the analysis. A structural equation modeling was performed to test the hypothesized relationships. The results revealed that body surveillance and social ostracism influenced the individuals’ cutaneous body image dissatisfaction, which also influenced perceived attractiveness and fitness of tanned appearance. Perceived tanning attractiveness and perceived tanning physical fitness positively influences attitudes toward tanning product use. It is evident that seeing one’s own body through the lens of others is at the root of positive attitudes toward sunless tanning products. Positive attitudinal changes toward sunless tanning products can be successfully established emphasizing sunless tanning products as fashion consumption. The findings in this study have important relevance, in that tanning products can be marketed as cosmetic appearance-enhancement products for people to look attractive, toned, and fit.

      • 신고리 지역 기상관측을 통한 계절별 대기안정도 특성분석

        송상근,김유근,오인보,정주희,조윤미,우경은,강태훈 부산대학교 환경문제연구소 2003 環境硏究報 Vol.21 No.-

        In this study, we analyzed the characteristics of atmospheric stability to investigate local environment change at an atomic power plant in Gori region. The used data was obtained from field observation of major meteorological variables such as wind direction and speed, air temperature, relative humidity, and solar radiation using AWS (Automatic Weather System) in Gori region from February to September in 2003. As a result, when strong northerly winds (more than 4~6 m/s) and weak northwesterly winds (2~3m/s) blow, atmospheric stability was neutral and stable from winter to spring, respectively. Atmospheric stability (neutral) in summer was similar to that in two other seasons (winter and spring), but it was stable for weak southwesterly winds (2~3 m/s). Finally, atmospheric stability was neutral for strong winds (over 4~6 m/s) in fall without respect to wind direction, while that was stable for very weak winds (less than 2 m/s).

      • 국내 상급종합병원과 종합병원 간호사의 정맥주입간호실무지침의 확산정도

        은영(Young Eun),구미옥(Mee Ok Gu),조용애(Young Ae Cho),정재심(Jae Shim Jeong),권정순(Jeong Soon Kwon),유정숙(Cheong Suk Yoo5),정영선(Young Sun Jeong),정인숙(In Sook Jung),김경숙(Kyeong Sug Kim),이선희(Seon Heui Lee),서현주(Hyun Ju S 한국근거기반간호학회 2015 근거와 간호 Vol.3 No.1

        Purpose: This study was conducted to investigate the extent of diffusion of Intravenous infusion nursing practice guideline among nurses in advanced general hospitals and general hospitals in Korea. Methods: The subjects were 234 nurses who practice the intravenous infusion in 24 advanced general hospitals and general hospitals. Data were collected between October 5 and November 2, 2015 by mail (return rates: 97.5 %). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/ WIN 21. Results: The average guideline diffusion score and levels of diffusion was 3.39±0.58 (level of “use sometimes”). 44 recommendations (46%) were in level of “use always” and 50 recommendations (53%) were in “use sometimes”. Extent of diffusion were significantly different according to present status (F=2.81, p=.040) and education (F=4.35, p=.014). The facilitating factors to use the guideline were education by department of nursing service, convenient composition of guideline and barrier factors were “no time to use the guideline”, “don’t know the guideline” and “there is no guideline at ward”. Conclusion: Extent of diffusion of Intravenous infusion nursing practice guideline among nurses was moderate level. The strategies for promoting the implementation of guideline in clinical practice is needed. Further study of outcome evaluation of guideline implementation will be needed.

      • SCOPUSKCI등재

        Acute kidney injury in patients with acute-on-chronic liver failure: clinical significance and management

        ( Jeong-ju Yoo ),( Moo Yong Park ),( Sang Gyune Kim ) 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.3

        Acute-on-chronic-liver failure (ACLF) refers to a phenomenon in which patients with chronic liver disease develop multiple organ failure due to acute exacerbation of underlying liver disease. More than 10 definitions of ACLF are extant around the world, and there is lack of consensus on whether extrahepatic organ failure is a main component or a consequence of ACLF. Asian and European consortiums have their own definitions of ACLF. The Asian Pacific Association for the Study of the Liver ACLF Research Consortium does not consider kidney failure as a diagnostic criterion for ACLF. Meanwhile, the European Association for the Study of the Liver Chronic Liver Failure and the North American Consortium for the Study of End-stage Liver Disease do consider kidney failure as an important factor in diagnosing and assessing the severity of ACLF. When kidney failure occurs in ACLF patients, treatment varies depending on the presence and stage of acute kidney injury (AKI). In general, the diagnosis of AKI in cirrhotic patients is based on the International Club of Ascites criteria: an increase of 0.3 mg/dL or more within 48 hours or a serum creatinine increase of 50% or more within one week. This study underscores the importance of kidney failure or AKI in patients with ACLF by reviewing its pathophysiology, prevention methods, and treatment approaches.

      • KCI등재

        Recent research trends and updates on nonalcoholic fatty liver disease

        Jeong-Ju Yoo,김원,Moon Young Kim,김상균,Jong Eun Yeon,이진우,조용균,Sang Hoon Park,Joo Hyun Sohn,KASL-KNSG 대한간학회 2019 Clinical and Molecular Hepatology(대한간학회지) Vol.25 No.1

        Nonalcoholic fatty liver disease (NAFLD), together with metabolic syndrome and obesity, has shown a rapid increase in prevalence worldwide and is emerging as a major cause of chronic liver disease and liver transplantation. Among the various phenotypes of NAFLD, nonalcoholic steatohepatitis (NASH) is highly likely to progress to development of endstage liver disease and cardiometabolic disease, resulting in liver-related and non-liver–related mortality. Nonetheless, there is no standardized pharmacotherapy against NASH and many drugs are under development in ongoing clinical trials. To develop a successful anti-NASH drug, it is necessary to select an appropriate target population and treatment outcomes depending on whether the mode of action is anti-metabolic, anti-inflammatory or anti-fibrotic. Recently, innovative surrogate markers have been investigated to replace hard outcomes such as liver histology and mortality and reduce the clinical trial duration. Currently, several drugs with fast track designation are being tested in phase III clinical trials, and many other drugs have moved into phase II clinical trials. Both lean NAFLD and typical obese NAFLD have been extensively studied and genetic variants such as PNPLA3 and TM6SF2 have been identified as significant risk factors for lean NAFLD. In the near future, noninvasive biomarkers and effective targeted therapies for NASH and associated fibrosis are required to develop precision medicine and tailored therapy according to various phenotypes of NAFLD.

      • KCI등재

        Distribution Characteristics of Dioxins in Soils under Different Land Use in Busan, Korea

        Jeong, Tae-Uk,Seo, Dong-Cheol,Jeong, Seung-Ryul,Cho, Jeong-Gu,Yoo, Pyung-Jong,Kim, Gi-Gon,Cho, Ju-Sik,Heo, Jong-Soo Korean Society of Soil Science and Fertilizer 2011 한국토양비료학회지 Vol.44 No.4

        In this study, distribution characteristics of dioxins in soils in Busan, Korea were investigated regarding different land use types. Soil sampling sites that distributed through the Busan city showed dioxin concentration ranging from 0.489 to $322.736pg-TEQ\;g^{-1}$ dry weight with a mean value of $26.257pg-TEQ\;g^{-1}$ dry weight. The mean dioxin concentrations of investigated soils ranged from 1.554 to $50.357pg-TEQ\;g^{-1}$ dry weight in consideration of each land use type. That in metal refinery sites with $50.357pg-TEQ\;g^{-1}$ dry weight was higher than any other sites, followed by waste incinerator sites with $44.285pg-TEQ\;g^{-1}$ dry weight. The majority of soil samples had the same dioxin congener profiling despite the different range of dioxin concentration. Octa-CDD was the major contributor among seventeen dioxin congeners with the range from 29.5 to 70.1% in real values. In contrast to real values, dioxin congener profiles in TEQ values were dominated by 2,3,4,7,8-PeCDF which contributed about 35.3~43.8% to the total dioxin concentrations. It was judged by these results that penta-CDF was the major contributor of soil samples in Busan city. The mean ratio of PCDFs/PCDDs in real values was about 0.71, but that in TEQ values was, in contrast to it, approximately 3.03.

      • Inhibitory Regulation of Chicken Mx against Avian Viruses in Chicken Spermatogonial Stem Cells

        Ju-Young Ji,Kuppannan Gobianand,Jong-Ju Park,Jin-Gu No,Ju Sung Yang,Man Sung Park,Dong Kee Jeong,Dong-Hoon Kim,Jin Ki Park,Sung-June Byun,Chang Sun Song,Jae Gyu Yoo 한국동물생명공학회(구 한국동물번식학회) 2013 Reproductive & Developmental Biology(Supplement) Vol.37 No.2s

        Mx is regulated by type I interferons and contains a typical GTP-binding motif like other members of the GTPase dynamin family. However, the functions and working mechanisms of the Mx protein in chicken spermatogonial stem cells (SSCs) are not well documented. In the present study, Mx-overexpressing chicken SSCs (chMx-SSCs) were established and the antiviral activity of chMx-SSCs against Newcastle disease virus, avian influenza viruses was investigated in vitro. For chicken SSCs isolation, day 20 fetal males derived testes were initially subjected to digestion by collagenase IV followed by 0.25% trypsin–EDTA. After discarding the supernatant, the cells were cultured in SSC medium. SSC colonies expressed pluripotent markers such as stagespecific embryonic antigen-1, Oct-4, Nanog, and Sox-2. Chicken Mx gene was constructed in plasmid DNA vector (pcDNA3.1/V5-His A-chMX) and ChMx-SSCs lines were established with chMX constructs. The antiviral activity of ChMx-SSCs was determined by real-time RT-PCR, flow cytometry, and western blot analyses after infection with Newcastle disease virus-green fluorescent protein (GFP) and avian influenza viruses (H9N2 and H1N1). ChMx-SSCs inhibited recombinant Newcastle disease virus (rNDV)- GFP replication as determined by the calculation of the proportion GFP signal- positive cells by FACS analysis. When SSCs showed 100% GFP expression, chMx- SSCs had only 3.6% GFP expression. At 24 h after avian influenza virus infection, chMx-SSCs had a lower hemagglutinin protein level and a higher level of Mx protein. When the number of released virion particles was estimated by plaque-formation assay, chMx-SSCs had significantly fewer stained visible plaques in the MDCK layer than SSCs. Our results suggest that overexpression of chicken Mx directly stimulates antiviral activity resulting in downregulation of viral progeny release. Chicken Mx overexpression in chicken SSCs can be applied for the production of virus resistant transgenic chicken via direct transplantation of chMx-SSCs into the testis.

      • KCI등재

        Prognostic Value of Biochemical Response Models for Primary Biliary Cholangitis and the Additional Role of the Neutrophil-to-Lymphocyte Ratio

        ( Jeong-ju Yoo ),( Eun Ju Cho ),( Bora Lee ),( Sang Gyune Kim ),( Young Seok Kim ),( Yun Bin Lee ),( Jeong-hoon Lee ),( Su Jong Yu ),( Yoon Jun Kim ),( Jung-hwan Yoon ) 대한소화기학회 2018 Gut and Liver Vol.12 No.6

        Background/Aims: Recently reported prognostic models for primary biliary cholangitis (PBC) have been shown to be effective in Western populations but have not been wellvalidated in Asian patients. This study aimed to compare the performance of prognostic models in Korean patients and to investigate whether inflammation-based scores can further help in prognosis prediction. Methods: This study included 271 consecutive patients diagnosed with PBC in Korea. The following prognostic models were evaluated: the Barcelona model, the Paris-I/II model, the Rotterdam criteria, the GLOBE score and the UK-PBC score. The neutrophil-to-lymphocyte ratio (NLR) was analyzed with reference to its association with prognosis. Results: For predicting liver transplant or death at the 5-year and 10-year follow-up examinations, the UK-PBC score (areas under the receiver operating characteristic curve [AUCs], 0.88 and 0.82) and GLOBE score (AUCs, 0.85 and 0.83) were significantly more accurate in predicting prognosis than the other scoring systems (all p< 0.05). There was no significant difference between the performance of the UK-PBC and GLOBE scores. In addition to the prognostic models, a high NLR ( >2.46) at baseline was an independent predictor of reduced transplant-free survival in the multivariate analysis (adjusted hazard ratio, 3.74; p<0.01). When the NLR was applied to the prognostic models, it significantly differentiated the prognosis of patients. Conclusions: The UK-PBC and GLOBE scores showed good prognostic performance in Korean patients with PBC. In addition, a high NLR was associated with a poorer prognosis. Including the NLR in prognostic models may further help to stratify patients with PBC. (Gut Liver 2018;12:714-721)

      • Relationship between Timing of Endoscopy and Mortality in Cirrhotic Patient with Variceal Bleeding

        ( Jeong-ju Yoo ),( Young Chang ),( Eun Ju Cho ),( Sang Gyune Kim ),( Young Seok Kim ),( Yun Bin Lee ),( Jeong-hoon Lee ),( Su Jong Yu ),( Yoon Jun Kim ),( Jung-hwan Yoon ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The optimal timing of emergency endoscopy in patients with variceal bleeding is remains unclear. Most guidelines recommend performing endoscopic evaluation and treatment within 12 hours after patient’s arrival, but there are few related studies. The aim of this study was to examine the association between timing of endoscopy and mortality of esophageal variceal bleeding in cirrhotic patients. Methods: This retrospective study included 274 of consecutive patients admitted to two tertiary hospitals in Korea due to esophageal variceal bleeding. Using descriptive statistics and Kaplan-Meier survival analyses, we analyzed the association between the timing of endoscopy and patients’ mortality. We adjusted confounding factors and balanced the baseline characteristics of the subjected patients using Cox proportional hazards model and inverse probability weighting (IPW) method. Results: A total of 173 patients received endoscopy within 12 hours after admission and 101 patients, after 12 hours. Endoscopy was performed after a median of 7.6 hours (interquartile range [IQR], 2.9-16.5) after admission. The median overall survival (OS) was 8.2 months (IQR, 1.4-25.9) months, and in-hospital mortality was 8.0%. Performing endoscopy within 12 hours was associated with longer OS than performing after 12 hours (33.2 vs. 23.5 months, log-rank P=0.01). Early endoscopy was independently associated with longer OS after adjusting presence of hepatocellular carcinoma, MELD score, and Glasgow-Blatchford score (adjusted hazard ratio [aHR] 1.61, 95% confidence interval [CI]=1.05-2.46, P=0.03). Also, after balancing baseline characteristics using IPW, endoscopy within 12 hours group consistently showed longer OS than endoscopy after 12 hours group (aHR 2.17, 95% CI=1.56-3.03; P=0.03). However, outcomes were not significantly different between the urgent (within 6 hours) and early endoscopy groups. Conclusions: Timing of endoscopy is associated with mortality in patients with esophageal variceal bleeding. It is important to perform emergency endoscopy within 12 hours, especially for high-risk patients.

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