군 훈련병의 스트레스, 성인 주의력결핍 과잉행동장애 증상과 자살사고의 연관성에 관한 연구

이동윤,이철순,박철수,손진욱,김봉조,차보석,이소진 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:This study is conducted to investigate the effect of Attention Deficit and Hyperactivity Disorder(ADHD) symptoms on stress and suicide idea among 224 conscripts. Methods:Total number of subject is 224 conscripts. We evaluate symptoms of adult ADHD with Korean-Wender Utah rating scale(K-WURS) and Korean adult attention-deficit/hyperactivity disorder scale(K-AADHDS), stress with Brief Encounter Psychosocial Instrument-K(BEPSI-K), suicide idea with Scale for suicide ideation(SSI) after basic military training. Multivariate logistic analysis with backward stepwise selection is performed to evaluate risk factors of stress. Multiple linear regression analysis with stepwise selection is performed to evaluate association of suicide idea with adult ADHD symptoms. Results:Stress is significantly associated with K-WURS score, K-AADHDS score and SSI score(p<0.01, p<0.05, p<0.01). K-WURS score are significant risk factor of stress after basic military training(p<0.05, O.R : 1.034, 95% CI : 1.005-1.065). And K-WURS score influence suicide idea after basic military training(p<0.05, β : 0.031). Conclusion:The result suggests that K-WURS score might be a risk factor of stress and could affect suicide idea.

사례기반추론기법을 이용한 선체 횡부재 구조설계 지식 표현 방법론 연구

윤덕영,양동열,차명석 朝鮮大學校 機械技術硏究所 1998 機械技術硏究 Vol.1 No.1

This paper shows the knowledge representation method for the possibility of the automation of the design and modeling of ship web frame in the level of detailed design using parametric design and case-based reasoning technique. It turns out that Case-Based Reasoning(CBR) based on casual model is successfully applied for the design automation.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

Tripledecker 착물, (CpCo)_2(C_4R_4)과 Alkyne과의 반응

嚴在國,李元植,金碩峯,車震淳,李炯秀,李東鎬,金洪碩,沈相喆 대구효성가톨릭대학교 자연과학연구소 1993 基礎科學硏究論集 Vol.1993 No.1

트리플데카 착물류, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt들은 Jonas시약과 2-hexyne 또는 3-hexyne을 실온에서 동량으로 반응시킬때, 50% 이상의 최대 수율이 얻어졌다. 한 종류의 트리플데카 착물인 bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt(13)는 실온에서 3-hexyne과 반응시키면, 착물 (η^5-cyclopentadienyl)cobalt-acyclopentadiene-μ-(η^4-2,4-cobaltacyclope-ntadiene)(η^5-cyclopentadienyl)cobalt(15)로 이성화되었다. 다른 한 종류의 트리플데카 착물, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,3-dimethyl-2,4-dipropyl-cyclobutadiene)dicobalt(14)를 2-hexyne 과 반응시켰더니 1,3,5-tri-methyl-2,4,6-tripropyl benzene화합물이 생성되었다. The tripledecker complexes, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt were produced by the reaction of Jonas reagent with 2-hexyne and 3-hexyne in the maxi-mum yield(above 50%) when they were reacted in eq-molar amounts at room temperature. A tripledecker complexes,bis-(η^2-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt(13) was isomerized to (η^5-cyclopentadienyl)cobalt-acyclopentadiene-μ-(η^4-2,4-cobaltacyclope-ntadiene)(η^5-cyclopentadienyl)cobalt(15) on reacting with 3-hexyne at room temperature. Another tripledecker complex, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,3-dimethyl-2,4-dipropyl-cyclobutadiene)dicobalt(14) was decomposed to give 1,3,5-trimethyl-2,4,6-trip-ropylbenzene through an intermediate complex by the reaction of 2-hexyne.

동아의료원에서 실시한 양수천자 90례의 세포유전학적 분석

한진영,이경미,신상동,차문석,제구화 동아대학교의과대학 1997 동아의대학술지 Vol.9 No.2

感冒처방 晴崗醫鑑 '加味普正散'의 의학역사적 이해

이병욱(Byung-Wook Lee),김동율(Dong-Ryul Kim),차웅석(Wung-Seok Cha) 한국의사학회 2011 한국의사학회지 Vol.24 No.2

This paper aims to find out the unique Oriental Medical characteristics of the prescription Gami-Bojeongsan(加味普正散), which can only be found in 『Cheong-gang Euigam(晴崗醫鑑』 and the records of diagnosis by Kim Yeong Hoon. First, clues regarding Gami-Bojeongsan (加味普正散) in 『Cheong-gang Euigam(晴崗醫鑑)』 and the records of diagnosis by Kim Yeong Hoon have been collected, and then the origin of Gami-Bojeongsan(加味普正散) has been studied. Moreover, changes of prescriptions for common cold in East Asian Medicine have been looked into from historical perspective, and their connection to Gami-Bojeongsan(加味普正散) has also been researched. Lastly, connection of prescriptions for common cold found in royal records of the Chosun Dynasty to Gami-Bojeongsan(加味普正散) has been confirmed. The results are as follow: 1) Gami-Bojeongsan(加味普正散) is a most frequently used prescription in the records of diagnosis by Kim Yeong Hoon, and was used mostly in winter. It includes various modified versions. 2) Prescriptions that adopt Cyperi Rhizoma(香附子) as the sovereign medicinal, such as Gami-Bojeongsan(加味普正散), include Hyangsosan(香蘇散) of 『Hejijufang(和剂局方)』 and Hyang-gal-tang (香葛湯) of 『Dexiaofang(得效方)』 Hyang-gal-tang(香葛湯) is thought to have adopted Korean characteristics through Dong-Eui-Bo-Gam(東醫寶鑑) and 『Je-Jung-Shin-Pyeon』 and have continued its existence until it reached Gami-Bojeongsan(加味普正散) 3)These characteristics can be found in the royal records of the Chosun Dynasty, and also in Shin-Su- Tae-Eul-San(神授太乙散) of 『Euibang-Yuchui (醫方類聚)』.

Influence of Ginseng Saponins on the Isolated Aortic Contractile Response of the Spontaneously Hypertensive Rat

Dong-Yoon Lim(Dong-Yoon Lim),Dong-Seok Cha(Dong-Seok Cha) 고려인삼학회 2002 Journal of Ginseng Research Vol.26 No.4

The present study was attempted to investigate the effects of total ginseng saponin (GTS), panaxadiol-type (PDS) and panaxatriol-type saponin (PTS) on contractile responses of vasoconstrictors in aortic smooth muscle stripes of normotensive (NR) and spontaneous hypertensive rats (SHR). Phenylephrine (an adrenergic α1-receptor agonist) and high potassium (a membrane depolarizing agent) caused greatly contractile responses in both NR and AHR aorta, respectively. Phenylephrine- and high potassium-induced contractile responses were greater in NA than those in SHR aortic smooth<br/> muscle stripes. In NR, the contractile responses of high potassium (5.6×10.2 M) were not affected in the presence of GTS (300 μg/ml), PDS (300 μg/ml), and PTS (300 μg/ml), respectively whereas phenylephrine (10.6 M)-induced contractile responses were markedly inhibited. In SHR, the contractile responses of high potassium (5.6×10.2 M) were not affected in the presence of GTS (300 μg/ml), PDS (300 μg/ml), and moderate doses of PTS (150-300 μg/ml), respectively but greatly blocked by high concentration of PTS (600 μg/ml). Phenylephrine (10.6 M)-induced contractile responses were<br/> inhibited in a dose dependent fashion (150-600 μg/ml) by the pretreatment with PTS while not altered in the presence of GTS (300 μg/ml) and PDS (300 μg/ml), respectively. Taken together, these experimental results suggest that ginseng saponins cause vascular relaxation through blockade of adrenergic α1-receptors and some unknown mechanisms, and that there is some difference in sensitivity of vascular smooth muscle between NR and SHR in responses to ginseng saponins. It seems that panaxatriol type of some ginseng saponins has the greatest potency in vascular relaxation.

Differential subcellular localization of DNA topoisomerase-1 isoforms and their roles during <i>Caenorhabditis elegans</i> development

Cha, Dong Seok,Hollis, Sarah E.,Datla, Udaya Sree,Lee, Sejin,Ryu, Jinsun,Jung, Hey Rim,Kim, Eunsuk,Kim, Kyuhyung,Lee, Myeongwoo,Li, Chris,Lee, Myon-Hee Elsevier 2012 Gene expression patterns Vol.12 No.5

<P><B>Highlights</B></P><P>► TOP-1β is broadly expressed in the nuclei of cells and concentrated in nucleoli. ► TOP-1α is specifically localized to centrosomes, neuronal cells, excretory cells and chromosomes of germ cells. ► TOP-1 proteins are required for chromosomal segregation and germline development in <I>Caenorhabditis elegans</I>.</P> <P><B>Abstract</B></P><P>DNA topoisomerase-1 (TOP-1) resolves the topological problems associated with DNA replication, transcription and recombination by introducing temporary single-strand breaks in the DNA. <I>Caenorhabditis elegans</I> TOP-1 has two isoforms, TOP-1α and TOP-1β. TOP-1β is broadly localized to the nuclei of many cells at all developmental stages and concentrated in nucleoli in embryo gut and oogenic cells. However, TOP-1α is specifically localized to centrosomes, neuronal cells, excretory cells and chromosomes of germ cells in embryonic and larval stages. Reporter gene analysis also shows that <I>top-1</I> transcription is highly activated in several sensory neurons, speculating the possible role of TOP-1α in neuronal development. From RNA interference (RNAi) experiments, we demonstrated that <I>C. elegans</I> TOP-1 is required for chromosomal segregation, germline proliferation and gonadal migration, which are all correlated with the expression and activity of TOP-1. Therefore, our findings may provide an insight into a new role of TOP-1 in development of multicellular organisms.</P>

초등학생의 부정적 스마트폰 사용행태가 건강에 미치는 영향: 부모양육태도의 조절효과를 중심으로

차동석 ( Cha Dong-seok ) 한국학교사회복지학회 2017 학교사회복지 Vol.0 No.38

본 연구의 목적은 초등학생의 부정적 스마트폰 사용행태와 부모의 양육태도가 아동·청소년의 건강에 미치는 영향을 탐색하고, 이를 바탕으로 부모양육태도가 부정적 스마트폰 사용이 건강에 미치는 영향을 조절(완화)하는지 분석하는 것이다. 이를 위해 경북지역의 초등학생 761명을 대상으로 구조화된 설문지를 통해 자료를 수집하고, SPSS 20.0 통계프로그램을 이용하여 다중회귀분석(Hierarchical Multiple Regression)하였다. 연구결과 첫째, 스마트폰의 부정적 사용행태는 아동·청소년의 신체적, 정신적, 사회적 건강에 부정적인 영향을 미치는 것으로 나타났다. 둘째, 부모의 양육태도가 수용-자율통제적일수록 아동·청소년의 신체적, 정신적, 사회적 건강에 유의미한 영향을 미치는 것으로 나타났다. 셋째, 부모의 수용-자율통제적 양육태도는 부정적 스마트폰 사용이 아동·청소년의 신체적, 사회적 건강에 미치는 영향을 완화하는 것으로 나타났다. 이러한 연구 결과는 아동·청소년의 건강을 위해 올바른 스마트폰 사용 교육과 더불어 부모의 올바른 양육태도의 필요성을 시사한다. The purpose of this study is to investigate the effects of the negative smartphone usage of elementary school students and parenting attitudes on the health of children and adolescents and based on this, analyze whether parenting attitudes moderate the effects of the negative smartphone use on health.For this, a structured questionnaire was conducted on 761 elementary students in Gyeongbuk province for the collection of data, and Hierarchical Multiple Regression was performed by using SPSS 20.0 statistical program. As a result, first the negative usage of the smartphone was found to give negative effects to the physical, mental, and social health of children and adolescents. Second, as the parenting attitude is more accepting and self-regulating, significant effects on the physical, mental, and social health of children and adolescent are more increased. Third, the accepting and self-regulating parenting attitude was found to relieve the effects of the negative smartphone usage on the physical and social health of children and adolescents.This result suggests the necessity of right parenting attitudes along with education on right smartphone usage for the health of children and adolescents.

Projections of High-resolution Climate Changes over South Korea using Five RCMs Based on the Four RCP Scenarios

Myoung-Seok Suh,Seok-Geun Oh,Joong-Bae Ahn,Dong-Hyun Cha,Dong-Kyou Lee,Seung-Ki Min,Seong-Chan Park,Hyun-Suk Kang 한국기상학회 2015 한국기상학회 학술대회 논문집 Vol.2015 No.10