혈우병 소견을 가진 뇌출혈 환자 치험(治驗) 1례(例)

정인태,서병관,이현종,하지영,강미경,홍장무,백용현,박동석,최도영,Jung, In-tae,Seo, Byung-kwan,Lee, Hyun-jong,Ha, Ji-young,Kang, Mi-kyeong,Hong, Jang-moo,Baek, Yong-hyeon,Park, Dong-suk,Choi, Do-young 대한침구의학회 2003 대한침구의학회지 Vol.20 No.4

Objective : Hemophilia, a genetically determined disorder, is characterized by abnormality of the coagulation mechanism due to functional deficiency of a specific factor, namely VIII or IX. In this study, the effect of Dong-Si acupuncture therapy on the cerebral hemorrhage patient with hemophilia was evaluated. Methods : We treated him with acupuncture by stimulating Dong-Si acupuncture point(Yuk Wan) and assessed the effect by using manual dynamic evaluation of MRC(Medical Research Council) and Modified Barthel Index. Results : After treatment, the bleeding tendency was grossly reduced and bleeding lesion was absorbed gradually. And manual dynamic evaluation of the upper extremity increased from 4 grade to 5 grade. Conclusions : This result suggest that Dong-Si acupuncture therapy on the cerebral hemorrhage patient with hemophilia was effective. And futher studies are required to concretely prove the effectiveness of Dong-Si acupuncture therapy for treating hemorrhagic diseases.

갑상선 종양에서 thrombin receptor (PAR-1)의 발현 양상

박지영,목지오,김여주,박형규,김철희,변동원,서교일,유명희,조현득,오미혜,김상진 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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잠김 금속판을 이용한 대퇴골 전자하 골절의 치료 : 압박 고 나사와 비교

손현철, 김용민, 김동수, 최의성, 박경진, 조병기, 박지강, 배승환 충북대학교 의과대학 충북대학교 의학연구소 2011 忠北醫大學術誌 Vol.21 No.2

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내시경적 절제로 진단된 폴립 형태의 심재성 낭종성 위염 2예

허종현,조영화,성용완,유재훈,구동영,김갑식,노지훈,문원 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Gastritis cystica profunda (GCP) is a disease characterized by hyperplastic and significant extension of cystic dilatation of the gastric mucous glands, which results in a cystic lesion in gastric submucosa. It often occurs on the part of gastroenterostomy, but can be found in the stomach without any previous surgery. GCP has variable gross finding including solitary polyps, diffuse ones, submucosal tumors, and rare giant gastric mucosal fold. It is difficult to tell GCP from a cancerous lesion by gross finding that the disease demands a necessary tissue biopsy, though GCP is commonly showed as a benign in the progress. We report a case of GCP in polypoid types diagnosed by endoscopic polypectomy.

편마비 환자의 정상측과 마비측의 비복근 운동점에서의 근육 두께 차이

김동건,도현경,김현동,황지선,정규영,정호중 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

Objective : To investigate any difference of muscle thickness in the motor points of the gastrocnemius between the paretic and non-paretic legs in hemiplegics. Method : Ultrasonography was used to assess in vivo the gastrocnemius muscle thickness at the motor points in the paretic and non-paretic legs of twenty-four patients with stroke. Results : Muscle thickness at the motor points were reduced in the paretic legs compared to the non-paretic legs (p<0.05). There was no correlation between muscle thickness and duration of hemiplegia, site of hemiplegia. However, it did not take regular pattern of the muscular atrophy in the paretic legs. Conclusion : The gastrocnemius muscle of the paretic leg had smaller thickness compared with the non-paretic leg. The present results indicate that paresis in hemiplegics may affect the accuracy of intramuscular injection of botulinum toxin A. Therefore, we recommend ultrasonography for visually controlled, anatomically precise injection of botulinum toxins.

얼굴 연조직 강화를 위한 자가지방 이식 후 발생한 급성 경계부위 뇌경색

민경현, 이혜림, 여민주, 김지선, 이성현, 이상수, 신동익 충북대학교 의과대학 충북대학교 의학연구소 2016 忠北醫大學術誌 Vol.26 No.1

본문참고

인공지반의 조경적 활용에 관한 국내 연구동향 : 옥상녹화를 중심으로

김동찬,서주환,김옥경,승지현,김홍균,최선주,박선영 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

This study aims at understanding the trend of researches carried out on the subject of rooftop afforestation. The issue of rooftop afforestation is receiving attention as one of the plans to secure green zones in urban area. While the actual execution of rooftop afforestation in Korea in only in the initial state, thus in not activated, studies on this subject have been actively carried out particularly in terms of the methods of rooftop afforestation. Recently, studies are being actively performed on the creation and effect of rooftop afforestation. However, these studies tend to focus on specific areas. This leads to the necessity to approach the issue of rooftop afforestation with a wider perspective. Therefore, in the study, the previous studies on rooftop afforestation carried out both in and outside the country are categorized as the study on the methods, effect and activation plans of rooftop afforestation, thus are examined to understand the recent trend in the study of rooftop afforestation. The results indicate that domestic studies. which was centered on the methods to promote rooftop afforestation. have been expanding into the study on the methods to establish eco-habit at on rooftop as well as on the environmental and economic effect rooftop afforestation.

CAI를 활용한 프로그램이 청각장애아동의 듣기 및 말하기 능력 향상에 미치는 효과

이지현,석동일 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.1

The purpose of this study was to find out whether a child's hearing disorder was improved through CAI program. The experiment was conducted on three children with hearing disorder for fourty minutes a session, three times a week. The experiment was performed using subjects that consisted of three stages: baseline stage, treatment stage and maintenance stage. The ability to improve hearing and speaking was evaluated. The results were as follows; Firstly, the ability of hearing on different words through CAI program was improved after the treatment on all subjects. The result persisted. Secondly, the ability of hearing on various sentences through CAI program was improved after the treatment on all subjects. The result persisted. Finally, the subjects ability on speaking through CAI program was improved after treatment in all subject. The result persisted. CAI(Computer Assisted Instruction)를 활용한 프로그램은 소프트웨어 형태로서 컴퓨터에 프로그램만 설치하게 되면, 물리적인 공간에 상관없이 동일한 자극을 반복해서 줄 수 있다. 따라서 아동이 집에서 공부할 때도 치료사와 공부했던 기억을 되살리는 데 많은 도움을 주게 되며, 부모가 가정에서 지도 시 치료사와 동일한 자료로 공부하게 됨으로써 가정에서 교육할 때 교재로 인한 부담감을 줄일 수 있다. 또한 물리적 환경의 약점을 보완해 줄 수 있으며, 아동의 흥미를 유발하는 것과 동시에 집중력을 높여주고, 즉각적인 피드백을 제공하며 아동 스스로 프로그램을 진행시키면서 학습할 수 있다는 데 본 연구의 필요성을 가진다. 이와 같은 필요성에 기초하여 본 연구에서는 CAI를 활용한 프로그램이 청각장애 아동의 듣기 및 말하기 능력에 미치는 효과를 밝히는데 목적을 두었다. 이 연구의 대상자는 대구 OO 치료실에 다니는 청각장애 아동 3명을 대상으로 하였으며, 사용한 CAI 프로그램은 언어치료실과 가정에서 사용할 수 있도록 Macromedia사의 Directer 8.5를 이용하여 CD-Title로 제작하였다. 이 연구는 세 명의 대상아동에 대한 CAI 프로그램의 효과를 평가하기 위해서 피험자 간 중다기초선 설계법(multiple baseline design)을 적용하였다. 본 연구는 CAI를 활용한 프로그램을 청각장애아동에게 적용시켰을 때, 단어수준 및 문장수준 듣기 능력 향상과 말하기 능력 향상에 대한 효과를 알아보기 위해서 실시하였다. 본 연구에서 얻은 주요 결과를 요약하면 대상 아동 모두에게서 단어수준과 문장수준에서 듣기 능력이 향상되었고, 아울러 말하기 능력도 향상되었다. 이 결과는 치료를 종결한 후에 실시한 유지평가에서도 유지되는 것으로 나타났다. 이런 결과에 비추어 CAI 프로그램은 청각장애아동 언어치료의 한계성을 극복할 수 있는 방법 중의 하나로 보여 진다.

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

여러 식품 및 사료로부터 분리된 미생물로부터 유용 박테리오신의 탐색

백현동,허지운 慶南大學校 附設 工業技術硏究所 1998 硏究論文集 Vol.15 No.3

박테리오신은 미생물로부터 생산되는 천연의 무독성 방부제로서 주목받고 있는 항균성 단백질이다. 단백질로 구성되어 있기 때문에 인체에 섭취되면 소화기관의 단백질 가수분해효소에 의해 분해되므로써, 인체에 무독하고 잔류성이 없다는 점에서 식품, 화장품, 농약 및 기타 분야에서의 천연 항생물질로서의 효용성이 증대되고 있다. 대부분의 박테리오신은 생산균주와 매우 가까운 그람 양성균만을 억제하는 매우 제한된 항균범위를 가지고 있어, 우수한 내열성에도 불구하고, 산업화하는데 문제점으로 지적되어 왔다. 따라서 본 연구에서는 여러 식품 및 사료로부터 GRAS로 인정받고 있는 유용 미생물을 분리하고, 이 분리균주들로부터 항균범위가 넓은 유용 박테리오신을 탐색하였다. 우선 각종 분리원에서 propionibacteria를 선택적으로 분리하기 위한 PAGSA배지를 확립하였다. 50종의 김치시료로부터 150종의 젖산균을 분리하였으며, 이 중에서 3종의 균주가 항균범위가 넓은 것으로 확인되었다. 그러나 주 항균효과가 젖산에 의한 가능성에 대해 향후 추가 실험이 필요하다. 치이즈로부터 15종의 미생물을 분리하고, 이 중 3종의 다른 propionibacteria를 확인하였고 많은 그람 음성균에 항균효과가 있슴이 확인되었다. Silage로부터 propionibacteria와 젖산균을 15종 분리하였으며, JWS15균주가 가장 항균범위가 넓은 균주로 밝혀졌고, 그람 음성균인 E. coli, Pseudomonas속균주에 항균효과가 있었다. 각종 식품으로부터 35종의 바실러스 균주를 분리하였으며, 이 중 SS704균주는 테스트한 대부분의 바실러스 균주와 대부분의 그람 음성균에 매우 큰 활성을 보였고, 주요 식물병원균인 Erwinia herbicola, Pseudomonas syringae, Xanthomonas campestris에 뚜렷한 항균활동을 보여 이 들 식물병원성균의 선택적인 방제에 활용이 가능하리라 판단된다. Bacteriocins are proteins produced by a heterogeneous group of bacteria have a bactericidal effect on closely related organisms. Because bacteriocins are natural products of many microorganisms associated with foods, there is currently an enhanced interest in their use as natural food preservatives. The GRAS microorganisms were isolated from various food and feed sources and the antibacterial activity of 215 isolates was determined by the deferred and a modified well diffusion assay. Bacillus strain SS704 showed a broad antibacterial spectrum of activity against all Gram-positive and Gram-negative bacteria tested, but not against yeasts tested. Especially, strain SS704 was active against major plant pathogens, such as Erwinia herbicola, Pseudomonas syringae, and Xanthomonas campestris. Thus, the exploitation of this strain in agriculture will be focused in the near future on the retardation of spoilage by plant pathogens and for grain preservation.