한국 도시생태환경 관리를 위한 비오톱 평가지표 개발

김영선 호남대학교 2014 국내박사

논 문 개 요 한국 도시생태환경 관리를 위한 비오톱 평가지표 개발 제 출 자 김영선 지도교수 오구균 본 연구에서는 한국의 도시생태환경 관리를 위한 포괄적 지도화 방법에 적용가능한 공통된 평가지표를 도출하였다. 이를 위해 국내·외에서 비오톱에 관한 기존문헌을 토대로 상위 비오톱 평가요인을 구분하고, 델파이기법을 통한 평가지표 도출, 의사결정나무(CHAID)방법을 통한 평가지표의 설명예측력을 분석하였다. 이 결과를 토대로 포괄적 지도화 방법에 적용가능성을 검토하였다. 본 연구결과는 다음과 같다. 첫째, 상위 비오톱 평가요인은 생물적 요인, 무생물적 요인, 인간행태적 요인 등 3개 요인으로 구분하였다. 둘째, 델파이기법을 통해 도출한 비오톱의 평가지표는 생물적 요인에서 층위구조와 식생유형, 무생물적 요인에서 하천정비종류와 천이진행단계, 인간행태적 요인에서 산림훼손유형과 인공림 위치 등 총 6개 지표이었다. 또한 비오톱 평가지표의 가중치는 식생유형(0.980)이 가장 높게 나타났으며, 산림훼손유형(0.935), 층위구조(0.940), 하천정비종류(0.888), 인공림 위치(0.717), 천이진행단계(0.552) 순으로 높게 나타났다. 셋째, 의사결정나무(CHAID)방법을 통한 평가지표의 설명예측력 분석결과 비오톱 평가지표는 식생유형, 층위구조, 천이진행단계, 하천정비종류, 산림훼손유형 5가지 지표로 도출되었다. 하지만 5개 지표는 한국의 도시생태환경 관리를 위한 비오톱 평가지표로 적용하기엔 지표의 편중, 지표의 중복성, 용어의 혼용 등 대표성이 부족한 결과로 나타났다. 넷째, 한국의 도시생태환경 관리를 위한 포괄적 지도화 방법에 적용가능한 비오톱 평가지표는 자연성(헤메로비) 등급, 층위구조, 천이진행단계, 하천정비종류 4가지 지표로 도출되었다. Abstract Evaluation Index of Biotopes for Urban Environment Management in Korea Kim Young-Sun Directed by Prof. Oh, Koo-Kyoon Dept. of Landscape Architecture, Graduate School, Honam University, Gwangju, Korea Derived in this study are commonized evaluation indicators that are applicable to the comprehensive mapping method for the management of urban ecological environment in Korea. To this end, based on the existing domestic and overseas literature on biotope, the top-level biotope evaluation factors were identified and the descriptive predictability of evaluation indicators, which were derived through the Delphi technique and the decision tree(CHAID) method, was analyzed. Based on these results, the applicability to the comprehensive mapping method was discussed. The results of this study are as follows. First, the top-level biotope evaluation factors were divided into 3 factors: biological factors, abiological factors and human behavioral factors. Second, the biotope evaluation factors derived through the Delphi technique were comprised of a total of 6 indicators: layer structure in biological factors, type of vegetation in biological factors, type of river maintenance in abiological factors, transition phase in abiological factors, type of deforestation in human behavioral factors, and location of artificial forests in human behavioral factors. In addition, regarding the weighted values for the biotope evaluation indicators, the type of vegetation (0.980) was found to be the highest, followed by, in a descending order, the layer structure (0.940), type of river maintenance (0.888), location of artificial forests (0.717), and the transition phases (0.552). Third, as a result of analysis of the descriptive predictability of the evaluation indicators through the decision tree (CHAID) method, 5 biotope evaluation indicators were derived: type of vegetation, layer structure, transition phase, type of river maintenance and type of deforestation. However, the 5 indicators were found to be insufficient to be applied as biotope evaluation indicators for the management of urban ecological environment in Korea due to their biasness, redundancy, mixed use of the terms, etc. Fourth, the biotope evaluation indicators applicable to the comprehensive mapping method for the management of urban ecological environment in Korea were derived as 4 indicators: nature characteristic (hemeroby) level, layer structure, transition phase and type of river maintenance.

산뽕나무에서 분리한 2,5'-dihydroxy-4,3'-di(β-D-glucopyranosyloxy)-trans-stilbene의 생리활성 평가

김영선 강원대학교 2006 국내박사

생체내에 존재하는 활성산소와 관련된 자유라디칼은 노화, 염증, 동맥경화, 혈관질환 및 암 등과 같은 여러 가지 질병들과 관련되어 있다. 자연계에 존재하는 많은 천연물로부터 활성산소 장해를 방해하는 항산화 물질 등과 같은 생리활성 물질이 질병에 대한 치료제로서의 가능성과 연계되어 많은 주목을 받고 있다. 따라서 본 연구는 산뽕나무(Morus bombycis Koidzumi) 추출물을 대상으로 항산화 활성이 있는 화합물을 단리하였고 약리작용으로 간 기능에 미치는 영향 및 항당뇨 작용 등 다각적인 생리활성을 탐색하였다. 산뽕나무의 생리활성 기능을 탐색하기 위하여 부위별로 각종 추출물을 조제하여 분석한 결과 80% 메탄올 뿌리 추출물에서 높은 항산화 활성을 나타내었다. UVB 및 UVA 영역에서의 자외선 차단효과에서는 80% 에탄올 뿌리 추출물과 80% 메탄올 뿌리 추출물에서 자외선 흡수력이 높게 측정되었다. 항산화 효과 및 자외선 차단효능이 탁월한 산뽕나무 뿌리 추출물을 ESR spectrometer로 superoxide radical 소거 활성을 측정한 결과 뿌리 물 추출물에서 가장 높았다. 100 mg/kg body의 물 추출물을 투여한 군은 사염화탄소군보다 유의적인 간보호 활성을 나타내었다. 또한 뿌리 물 추출물은 FeCl2-ascorbic acid에 의해 유도된 쥐 간균질물의 과산화지질에 대한 억제작용을 나타냈다. 항산화 활성이 높은 산뽕나무 80% 메탄올 뿌리 추출물에서 분리, 동정하여 2,5'-dihydroxy-4,3'-di(β-D-glucopyranosyloxy)-trans-stilbene (DGTS)인 화합물을 밝혀냈다. ESR에 의한 superoxide radical의 소거활성을 측정한 결과 소거활성이 높게 나타났고 과산화지질의 억제작용도 높았다. 이 stilbene 화합물로 사염화탄소에 의한 간보호 기능에 미치는 영향을 알아본 결과 DGTS 투여군이 사염화탄소군보다 AST, ALT량이 유의적인 감소를 나타냈고 400~600 mg/kg body양으로 투여하였을 때 silymarin 100 mg/kg body 투여군과 비슷한 효과를 나타내었다. 사염화탄소에 의한 간손상 회복은 조직학적 관찰에서도 관찰할 수 있었다. 또한 DGTS의 항당뇨에 미치는 영향을 알아보았다. 결과 높은 α-amylase 저해활성을 나타내었고 STZ로 처리한 β세포인 HIT-T15에 대한 보호작용을 나타내었다. In vivo에서 STZ로 유도된 당뇨쥐에서 DGTS의 항당뇨 작용을 알아본 결과 DGTS 투여군의 혈청 AST, ALT, BUN, 과산화지질의 함량이 STZ군보다 유의적인 감소를 나타내었고 insulin함량은 유의적인 증가를 나타내었다. 췌장의 조직학적 관찰에서 보면 STZ군에서 췌장 β-cell이 많이 손상된 것을 알 수 있는 반면에 DGTS투여군에서는 β-cell이 많이 회복된 것을 관찰할 수 있었다. RT-PCR로 CYP2E1과 TNF-α의 발현량을 알아본 결과 STZ군에서 제일 강하게 발현되는 반면에 DGTS투여군에서는 STZ군보다 약하게 발현되였다. stilbene 화합물인 DGTS에 대한 생리활성연구를 통하여 간기능보호제, α-amylase 저해제와 항당뇨제로의 개발이 가능할 것으로 생각된다. Free radicals and other reactive oxygen species, from both endogenous and exogenous sources, are implicated in the etiology of several degenerative diseases, such as coronary artery diseases, stroke, rheumatoid arthritis, diabetes and cancer. Studies proved dietary intake of antioxidant compounds will reduce oxidative damage resulted from these free radicals. Synthetic antioxidants, such as butylated hydroxyanisole (BHA), have restricted use in foods as these synthetic antioxidants are suspected to produce side effects. Therefore, the search for natural antioxidants, especially of plant origin, has greatly increased in recent years. Morus bombycis Koidzumi is widely distributed in Asia and is used in traditional medicine on account of its apparent anti-inflammatory, antibiotic, and antioxidant effects, and its lowering of blood hyperlipemia. However, its mode of action is obscure. The present study was carried out for the purpose of developing antioxidant from Morus bombycis Koidzumi. When antioxidant activities were examined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical, the 80% methanol extract from the root of Morus bombycis Koidzumi showed strong antioxidant activity. While, aqueous extracts from the root of M. bombycis Koidzumi had higher superoxide radical scavenging activity than other types of extracts. The aqueous extract at a dose of 100 mg/kg showed significant hepatoprotective activity when compared with that of a standard agent. The biochemical results were confirmed by histological observations indicating that M. bombycis Koidzumi extract together with CCl₄ treatment decreased ballooning degeneration. Also, the water extract recovered the CCl₄-induced liver injury and showed antioxidant effects in assays of FeCl₂–ascorbic acid-induced lipid peroxidation in rats. We have identified 2,5'-dihydroxy-4,3'-di(β-D-glucopyranosyloxy)-trans-stilbene(DGTS) as the active factor from Morus bombycis Koidzumi and investigated the protective effect of the purified compound against CCl₄-induced hepatotoxicity in rats and the mechanism underlying the protective effects. The DGTS displayed dose-dependent superoxide radical scavenging activity(IC50=430.2 μg/mL), as assayed by the electron spin resonance(ESR) spin-trapping technique. The increase in aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activities in serum associated with carbon tetrachloride(CCl₄)-induced liver injury was also inhibited by DGTS. The DGTS at a dose of 400~600 mg/kg had hepatoprotective activity comparable to the standard agent, silymarin. The biochemical assays were confirmed by histological observations showing that the DGTS decreased cell ballooning in response to CCl4 treatment. We also investigated DGTS effects on STZ-induced diabetes in rats. DGTS inhibited the increases in aspartate aminotransferase(AST), alanine aminotransferase(ALT) and blood urea nitrogen(BUN) in the serum associated with STZ-induced diabetes. At doses of 200~800 mg/kg, DGTS had antidiabetic activity comparable to the standard agent, tolbutamide. The biochemical assays were confirmed by histological observations showing that DGTS prevented atrophy of β-cells and vascular degenerative changes in the islets. DGTS reversed STZ-induced diabetes and had an antioxidant action in assays of lipid peroxidation in serum. Levels of cytochrome P450 2E1(CYP2E1) and TNF-α mRNA, as measured by RT-PCR, were lower in the livers of DGTS-treated rats than those of the control group. These results demonstrate that DGTS is an antidiabetic with a protective action against STZ-induced diabetes.

냉동만두류의 미생물학적 위해요소에 대한 노출평가 및 HACCP 모델개발

김영선 조선대학교 2011 국내박사

The purpose of this research is to offer scientific resources and activate HACCP application of frozen dumplings, to set critical control point/critical limit and develop education manual by conduct of hazrd factors and hazzrd analysis in the manufacturing process. To conduct of hazard factors of frozen dumplings had investigated references about manufacturing processes, raw materials, hazard factors of processes and HACCP model. To find the domestic hazardous factors and outbreak possibility, the diagrams of manufacturing processes and methods of 7 frozen dumplings manufacturers had been investigated in the fields, and other research papers and related literatures also had been surveyed. Sample preparation and analysis: Raw materials and sample contamination level of 238 manufacturing processes, surface contamination level of 70 manufacturing equipments, surface contamination level of 28 worker and aerial microbe of 74 work areas had been tested to find biological hazard factors, analyzed from 7 frozen dumplings manufacturers and for the verification of physical and chemical hazrd factors. Analyzed foodborne bacteria such as E. coli, E. coli O157:H7, B cereus, Staphylococcus aureus, Salmonella spp, and L. monocytogenes as well as total counts, yeast and mold, and coliform. Also, microbial analysis was compared between HACCP applied complany and non-HACCP applied company. As a results, total count and coliforms were decreased after steaming process. Toal counts and coliforms from raw materials were not decreased by washing process. The metal detection process was determined as CCPs. The CCP and critical limits for frozen dumplings were provide by evaluation the experimental results and literatures and then the HACCP plan was prepared. 5 Staphylococcus aureus, 5 Bacillus cereus, 2 E. coli and 2 Salmonella ssp. had been found in before steam process and this results were offered as the managerial sources of cross-contamination. Applying the test results and research data, conduct of hazard factors in the manufacturing process and evaluation of outbreak possibilities could be performed to develop HACCP models, so that it can be applied to more scientific and reliable certification process of HACCP and after-management. Also, hazard factors can be different because of the equipments and health control levels of each manufactururs. Data of this research could be cited with through self-verification. It is more easily than the current conduct of hazard factors and hazard analysis to reference the results from this research.

한라산 구상나무림의 임상변화와 직경생장 특성에 대한 고찰

金永善 국민대학교 1996 국내석사

GPS를 이용한 세부측량의 정밀도 분석

김영선 조선대학교 1996 국내석사

As a satelite positioning system, GPS is designed to provide the information on three dementional position, velocity, and time all over the world. Nowadays the use of GPS is highly admird in view of precision and economy, inside and outside the country. This study aimes to indicate a technique for practical using of GPS surveying to decide cadastral control points GPS surveying is carried out at cadastral points and supplementary control points. This paper includes uses of GPS in managing regional resource and controlling activities within large areas. GIS which is a computer based geographically oriented data base that helps manage resources on both regional and local levels. GPS ofen plays a key role in providing ground control for the base mapping. GPS can also be used- to update GIS information and enter new information in the file. I suggested potentiality of updating GIS information using GPS carrier phase by comparing result of point positioning, cadastral surveying, differential positioning, and combinations of methods.

『컴퓨터 일반』 교과서 구성체계의 개편방안

김영선 인하대학교 교육대학원 2008 국내석사

고도로 기술화되고 전문화되어 있는 현대사회에서 컴퓨터의 존재 중요성은 누구나 인지하고 있으며, 컴퓨터의 필요성은 지속적으로 커질 것이므로 컴퓨터 교육의 필요성에 대해서는 두말할 나위가 없다. 교육 분야에서의 컴퓨터의 존재는 시간과 공간에 제약을 넘어설 수 있는 학습도구로써의 무한한 활용을 제공하고 있다. 특히, 기본지식을 습득하기 위한 학교 교육을 통한 컴퓨터 교육은 국민전체의 기본 소양을 높이기 위하여 그 중요성이 크다고 할 수 있다. 상업계 고등학교에서의 컴퓨터 교육은 실생활에 도움이 되는 차원을 벗어나 직업 현장에서 직접적이고 곧바로 활용되어질 수 있는 실무 교육을 필요로 하는 바, 컴퓨터 일반 교과서의 중요성이 크다고 할 수 있다. 컴퓨터 일반 과목은 상업 정보 계열에서 컴퓨터를 입문하는데 필요한 기초 지식을 배양하고 실무 능력을 배양하기 위한 ‘자료 처리’, ‘정보처리 실무’, ‘프로그래밍 실무’, ‘사무 관리 실무’ 과목들의 선수 과목이므로 이들 과목에 대한 전문적인 이론 지식을 습득해야 하다. 컴퓨터 일반 교과서는 다른 교과보다는 실습위주의 구성을 취하고 내용전개를 하는 면이 많지만, 하루가 다르게 급변하는 지식을 전달하기 위해서는 새로운 형태와 구성의 교과서가 절실하다. 본 연구는 상업계고등학교 『컴퓨터 일반』교과서 구성 체계에 대한 개편방안을 제시하는 데 목적이 있다. 본 연구는 상업계고등학교의 실무기본과목인『컴퓨터 일반』3종 교과서의 구성 체계를 분석하고, 외국교과서인 일본의 『정보』교과서 2종을 선정하여 구성 체계를 비교ㆍ분석하였으며 실증분석을 통하여 상업계 교사들의 컴퓨터 일반 교과서에 대해 가지는 의견들을 조사하였다. 한국 3종 교과서와 일본 2종 교과서의 특성 및 내용 구성 분석한 결과를 살펴보면, 두 나라의 교과서 모두 설명식 중심으로 전개하는 유사한 학습전개방식을 취하긴 했으나 일본식 교과서가 그 구성적인 면에서 한국의 교과서와 차이점이 보이고 내용적인 면에서도 한국의 교과서보다 더욱 실생활에 관련된 내용을 다루고 있음이 밝혀졌으며, 한국의 교과서는 산업계 직무에 도움이 되는 내용이나 최신 경향을 반영하여 실무에 도움을 주는 데는 부족한 점이 있었다. 즉, 현재의 교과서가 많이 좋아진 점이 있지만 아직까지는 문자를 중심으로 이론적인 교과서로서의 부족한 점이 있고 개별주도 학습을 하기에 역부족이며 이에 따라 자기 주도적 학습 및 수준별 학습을 위한 교재로의 개편이 시급하다고 할 수 있다. 실증분석 결과에 따르면 현재 컴퓨터 일반 교과서는 학생들의 흥미와 관심을 유발시키는데 한계가 있고 학생들로 하여금 자기 주도적 학습과 개별학습을 하기에는 부족한 편으로 조사되었고 재 교과서는 학생들의 전반적인 수준을 두루 맞추지 못했으며 은 모듈식 교과서 체제의 구성에는 찬성하는 반응이 나타났다. 결론적으로 본 연구에서는 컴퓨터 일반 교과서를 분석하여 문제점을 반영한 모듈식 교과서를 제안한다. 현재 주를 이루는 강의 중심의 교수 방법에서 탈피하여 소규모 그룹 학습, 모듈화 된 교육과정 운영, 프로젝트 연계 수업 등을 통하여 내용 전달만을 위한 교재 개발인 아닌, 학습자 중심의 교재 개발로의 전환점으로서 모듈식 교과서를 제시한 것이다. 컴퓨터 일반 교과서의 분석과 개편방안에 대한 본 연구를 바탕으로 앞으로 좀 더 많은 연구가 이루어져 교육현장에서 보다 긍정적이며 적극적으로 활용되어 질 수 있는 자료가 출현하기를 기대한다. In the modernized era nobody deny the importance of the value of computers, and the necessity of computers is gradually increasing. so it is natural to say that the education for computers is greatly important. Especially, the school education for computer concerning to learn basic knowledge is very remarkable for enhancing common senses. Computer education in business high school is not only for the helping real life, but also needs teaching practical service, so textbook 'Introduction to computer' is greatly momentous. Although compared to other subjects 'Computer' textbook is organized to actual training, it isn't enough for current textbook to keep up with the rapidly changing society. This study is to propose a plan to restructure the Computer textbook 'Introduction to computer' in business high school. For this study, we analyzed the structure of four textbooks of 'Computer textbooks', which are one of basic practical subjects in business high school in Korea, and compared them with one Computer textbook in Japan. In addition, teachers’ opinions on 'Cost Accounting' were collected through empirical analysis. According to the results of analyzing the characteristics and contents of the three textbooks in Korea and the one in Japan, the three textbooks in Korea were similar in unit structure and contents, there are significant difference between them - ones in Japan have proved to have dealt with efficient way in industry. Namely, current textbooks in Korea are improved to some extent, It is still designed with character-based pattern and has difficulty in promoting self-learning study, making it necessary to make module-based and level-based textbooks. In this study, respecting the structure of 'Introduction to computer' textbooks and the modular textbook composition, the current Computer textbooks were known to be inadequate for stimulating students’ interests and for students’ self?directed learning, but the modular textbook composition was considered positively. On conclusion, based on the results of analyzing 'Introduction to computer' textbooks, we propose a modular textbook, reflecting problems in the current textbooks. A modular textbook arranges the contents systematically using modules that enable level?based learning, self?directed learning and individual learning.

우리나라 女性의 나트륨攝取量 測定 및 나트륨.칼슘代謝에 관한 硏究

김영선 淑明女子大學校 1987 국내석사

The purpose of this study was to measure daily Na intake, to find more accurate and suitable methods to estimate Na intake, and to examine the effect of dietary sodium on calcium excretion in 30 healthy Korean female college students. Dietary survey by food intake record and urine samples were collected for 3 consecutive days and duplicate food samples was collected on one of the 3 study days. Optimum gustation of salt was tested using beef broths with different salt concentration and blood pressure was measured from each subject. Nondiscretionary Na intake and intakes of K, Ca and animal protein from egg and meat were calculated by dietary intake record, total Na intake was measured by duplicate food samples, pooled 3-day urine samples were analyzed for mean 24-hour urinary Na, K. Ca, creatinine excretion. The results obtained were summarized as follows: 1. Mean age of subjects was 21.8±2.17, mean systolic and diastolic blood pressures were 112.8±7.8, 69.7±6.8 mmHg respectively. 2. From dietary intake record, mean daily intake of energy was 1652.27±312.07 Kcal, protein was 52.67±10.74g, carbohydrate was 283.03±63.87g, fat was 34.26±10.3g, providing 12.75%, 68.52%, 18.66% of total energy respectively. Mean daily intake of calcium was 509.26±208.32mg, phosphorus was 825.12±235.23mg, dietary Ca/P ratio was 1.62, potassium was 38.15 mEq.. 3. Mean values of total, discretionary and nondiscretionary Na intakes were 169.6 mEq., 46.2 mEq. and 123.4 mEq. respectively. Discretionary Na intake was about 72.8% of total Na intake. 4. Mean 24-hour urinary Na excretion was 137.9 mEq., which was about 84.5% of total Na intake. Mean 24-hour urinary K excretion and Na/K ratio were 33.69 mEq. and 2.58 respectively. Mean 24-hour urinary creatinine, Na/g creatinine excretion were 852.1mg, 176.61 mEq.Na/g creatinie respectively. Mean 24-hour urinary Ca excretion was 164.75mg. 5. Mean 24-hour urinary Ca excretion of subjects were significantly correlated with total Na intake (p < 0.05), mean 24-hour urinary Na excretion (p < 0.001), 24-hour urinary K excretion (p < 0.05), mean daily protein intake (p < 0.05). 6. Subjects with optimum gustation of salt equal to or higher than 0.5% had significantly higher total Na intake (p < 0.05), mean 24-hour urinary Na excretion (p < 0.001) and mean 24-hour urinary Ca excretion (p < 0.05) compared to subjects with optimum gustation of salt lower than 0.5%. 7. Total Na intake of subjects were significantly correlated with optimum gustation of salt (p < 0.001), nondiscretionary Na intake (p < 0.01), discretionary Na intake (p < 0.001), mean 24-hour urinary Na excretion (p < 0.001), mean 24-hour urinary Ca excretion (p < 0.05) but were not significantly correlated with systolic and diastolic blood pressure. 8. From multiple regression analysis, the best estimate of total Na intake is obtained when both optimum gustation of salt and nondiscretionary Na intake were used as independent variables (r = .7071). Among the equations using one independent variable, regression equation with mean 24-hour urinary Na intake provides the best approximation (r = .6627) of total Na intake. The above results show that an increase in the dietary intake of sodium increase the calcium excretion as well as sodium excretion in urine and total Na intakes of the subjects depend on discretionary Na intake. Thus, if the subjects decrease optimum gustation of salt, total Na intake would decrease.

조개류의 이미지를 응용한 다용도 합(盒) 제작에 관한 연구

김영선 檀國大學校 産業디자인大學院 2002 국내석사

인류의 정착생활이 시작된 이후 사회와 문명의 발달과 더불어 일상생활에 필요한 용기도 많은 변화와 발전을 거듭해왔다. 또한 농경생활의 시작으로 인해 양식의 저장과 보관에 필요한 용기를 제작하기 시작하였다. 다양한 용기의 종류 중 일상생활에 필요한 여러 가지 물건의 보호와 보관을 위하여 뚜껑이 얹힌 그릇을 만들게 되었으며 이러한 뚜껑있는 그릇, 즉 합(盒)은 도자기의 예술적 가치와 더불어 용과 미를 겸한 생활용기로서 일상생활과 밀접한 관계를 유지해 오면서 발전되어 왔다. 합은 실용적인 용기로서 종류와 용도가 광범위해 졌지만 시대속의 욕구에 충족될 수 있는 새로운 형태의 도자제 합(盒)으로 주변생활 공간과 잘 어울릴수 있는 디자인이 요구되어진다. 본 논문은 연구방법은 합(盒)의 개념과 시대성을 여러문헌을 통해 역사적으로 고찰하였고 현대사회에 쓰이고 있는 다양한 합의 종류를 분석 연구하였다. 또한 제품의 조형성과 다양하게 표현할 수 있는 디자인을 위해 조개류의 종류와 형태적 특징을 문헌과 실물을 보고 조개류의 디자인을 분석 하였다. 본 연구는 다양한 형태와 아름다운 색상을 가진 조개류를 소재로하여 인간에게 자연적 정서와 동감을 느낄수 있게 하고 실용성과 심미성이 추구된 다용도합(盒)을 제작하려는 목적을 가지고 있다. 또한 작품의 정신적 근원과 내적욕구의 연관성을 조개류와 돌의 형태를 통해 표현하려 하였으며 구체적 접근에 있어서는 조개류와 돌맹이의 자연스러운 형태에 조개류의 다양한 무늬를 응용해 장식해가는 방법을 주로 작업하였다. 제작방법은 틀을 제작함에 있어 돌맹이의 표면과 석고를 보다 쉽게 분리시키기 위해 리스를 바른후 틀을 만들거나 점토로 원형을 제작한 후 석고틀을 이용한 가압성형법을 사용하였으며 태토는 색감표현을 강조하기 위해 백토를 주로 사용하였고. 작품에 따라 부분적으로 백토에 조합토, 청자토를 혼합하여 사용하여 무늬를 자연스레 표현하고자 하였다. 본 논문의 시작품은 물레성형이나 주입성형과는 다른 제작방법을 통해 여러 가지 태토의 질감과 색감을 표현할 수 있었고 시유는 다양한 색유를 분무후 문양에 따라 닦아 내는 방법을 주로 사용하였으며 형태나 태토의 질감에 비례해 붓시유 기법도 부분적으로 사용하였다. 1차소성은 소지의 강도를 높이고 시유시 파손을 방지하기 위해 소성온도를 조금높여 900℃로 소성하였고 2차소성은 기물에 유약을 고르게 입히기 위해 담금 시유와 분무시유 후 1250℃로 소성하였다. 본 연구를 통해 조개류와 돌의 다양한 선과 무늬를 알게되었고 자연물을 소재로 다용도합(盒)을 제작함으로써, 보다 자연스럽고 친숙한 이미지의 다용도 합(盒)제작이 되었던 것 같다. Since men had settled down, society and culture developed. and along with that vessels for every-day life went through a lot of change & improvement. Agricultural activity made it necessary to produce vessels for the storage/depositing of grains . Among various kinds of vessels, the ones with 'lids ' were invented to protect / store lots of daily stuff. These vessels are called Converded Bowl and had artistic value as well as practicality, and got better and better in relation to every-day lives. Converded Bowl came to cover wide range of practical vessels. and now we need new designs of Converded Bowl of pottery to become well with surrounding modern living spaces. Research method of this thesis is the historical review of concept and stages of Converded Bowl by means of searching many related documents. Also, analization of kinds of Converded Bowl still used in modern times was performed. To get a variety of designs, we analized the patterns of shells by consulting records and real shells. The aim of this thesis is to make potteries with both practicality and beauty by using shells of variety of patterns and beautiful coiors. We tried to express the linkage between spiritual origin and internal desire of pieces of works by using patterns of shells and stones. In the approach, we applied many kinds of patterns of shells to natural shape of stones and shells. To easily separate the stones from plaster, we made molds after applying varnish to them. Or we first made molds of earth and then used press-forming method using plaster molds. For better color expression we mainly used white earth for body , and we partially used mixed clay and celadon clay for natural expression of patterns. A trial product of this thesis was made in methods different from throwing or slip casting to express various kinds of matiere (texture) and colors of body. We sprayed many colors of glaze and then scraped them of according to patterns. We partially used brush - glazing in proportion to the shape and matiere of body. The temperature of first firing was 900 degrees centigrade ( = slightly high ) to strengthen the ware sand to protect from breaking. The temperature of second firing was 1250 degrees centigrade to evenly coat glaze. As a result of this thesis we gathered many kinds of patterns of shells and stones. And by producing pottery work of natural material, we could create more unartificial, familiar images and designs.

Rat에서 인진쑥 배양 노루궁뎅이버섯 균사체(HEAC) 추출물과 그의 주성분들의 간손상 및 고지혈증 치료효과

김영선 순천향대학교 일반대학원 2010 국내석사

노루궁뎅이버섯 균사체를 인진쑥 배지에서 배양시킨 배양물(HEAC)을 80%(v/v) 에탄올로 추출하고, 추출물에 대하여 간손상 및 고지혈증 치료효과를 확인하였다. 사염화탄소 투여로 급성 간손상이 유발된 흰쥐에 대하여 80% 에탄올 추출물과 주요성분의 치료효과를 조사하였다. 그 결과, AST, ALT 감소율로서 80% 에탄올 추출물은 각각 75.2, 83.9%, 주요성분인 scoparone은 각각 78.3, 85.4%로 대조약제인 UDCA의 75.3, 85.4%와 유사한 급성 간손상 치료효과가 확인되었으며, 간세포 손상에 의한 간의 비대화에 대하여 80% 에탄올 추출물이 우수한 치료효과가 있는 것으로 확인되었다. 이러한 급성 간손상 치료효과 결과들을 살펴보면, 인진쑥의 성분이 배양 중 다른 성분으로 변화를 일으키며, 이들 성분이 UDCA와 유사한 급성 간손상 치료효과가 있음을 확인하였다. 또한, 고지방식이 급여로 간손상 및 고지혈증이 유발된 흰쥐에 대하여 80% 에탄올 추출물, 주요성분과 복합제의 치료효과를 조사하였다. 100 ㎎/㎏/day의 동일한 용량을 투여한 결과, AST, ALT 감소율로서 80% 에탄올 추출물은 각각 37.0, 64.7%, 주요성분인 ethyl linoleate는 각각 42.0, 68.6%로 대조약제인 simvastatin의 31.6, 58.7%과 유사한 치료효과가 확인되었으며, 간의 비대화와 간손상에 대한 조직학적 분석결과에서도 우수한 치료효과가 확인되었다. 심혈관 위험지수가 80% 에탄올 추출물은 1.95 ±0.13, 주요성분인 ethyl linoleate는 1.82 ±0.15로서 대조약제인 simvastatin의 2.56 ± 0.17과 유사한 치료효과가 있는 것으로 확인되었다. 단일제제로서 치료효과가 우수한 HEAC와 ethyl linoleate를 복합제제로 제조하여 효과를 조사한 결과, simvastatin과 HEAC가 각각 50%씩 함유된 100 ㎎/㎏/day 용량에서도 우수한 간손상 및 고지혈증 치료효과가 있는 것으로 확인되었다. 앞으로 독성 및 임상시험을 더 진행하여 HEAC 80% 에탄올 추출물과 HEAC-ethyl linoleate 복합제들은 새로운 간질환 및 심혈관계 질환 치료제 후보물질로 개발 될 수 있을 것으로 기대된다. 80%(v/v) ethanol extracts of Hericium erinaceum Hypha cultivated with Artemisia capillaris(HEAC) were prepared and assayed for evaluating their therapeutic effect on hepatic damage and hyperlipidemia induced by CCl4 and high fat diet. Extracts of HEAC with 80% ethanol showed potent therapeutic effect on hepatic damage and hyperlipidemia. After induction of acute hepatic damage by CCl4 and fatty liver, hyperlipidemia by high fat diet in rats, the extracts of HEAC, main components of HEAC, UDCA, simvastatin and mixture were administrated with continuous normal diet for 3 days and 2 weeks. And the serum level change of liver function, lipid metabolism, atherogenic index(AI), cardiac risk factor(CRF) and histological change of liver tissue were examined. With this result, serum concentration of AST and ALT were increased in CCl4 group compared with normal diet group. By treatment of HEAC, scoparone and UDCA with normal diet, their activities of AST and ALT were significantly decreased. AST and ALT decrease rate of HEAC, scoparone and UDCA is each 75.2, 83.9%, 78.3, 85.4% and 75.3, 85.4%. As well as, serum concentration of total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, AI, CRF, AST and ALT were increased in high fat diet group compared with normal diet group. By treatment of HEAC, ethyl linoleate, simvastatin and HEAC-ethyl linoleate mixture with normal diet, their activities of liver function, lipid concentration, AI, CRF and histological activities of liver tissue were significantly decreased. Among them, HEAC 100 ㎎/㎏/day and HEAC-ethyl linoleate mixture 200 ㎎/㎏/day showed strong therapeutic effect on hepatic damage and hyperlipidemia. Therefore, it might be considered as a potent candidate of new medicine as 80% ethanol extract of HEAC and HEAC-ethyl linoleate mixture for liver and cardiovascular diseases.

정공수송층/광활성층의 스프레이 증착을 이용한 유기 태양전지 제작

김영선 경북대학교 대학원 2011 국내석사

In this study, organic solar cells (OSCs) were fabricated by hole transport layer and active layer with substrate heating spray deposition method. As PEDOT:PSS (AI4083, PH500, PH750) was used as hole transport layer(HTL), and DMF and DMSO were added to the PEDOT:PSS for improving the conductivity of HTL. To confirm the characteristics of spray deposited HTL, conductivity, transmittance and surface morphology were measured. The modified PH750 was measured the conductivity of 77.28 S/cm, surface morphology of 83 nm, transmittance of 91% (at 400 nm ∼ 500 nm). The thickness of HTL was controlled by deposition time - 1 min, 2 min, and the OSCs which were fabricated in each condition were measured. The OSC which was fabricated with HTL deposited for 1 min was showed Voc of 0.62 V, Jsc of 14.02 mA/cm2, FF of 0.34 and PCE of 2.95%. OSC which were fabricated with HTL deposited for 2 min, was showed Voc of 0.61 V, Jsc of 9.56 mA/cm2, FF of 0.22 and PCE of 1.28%. Also HTL thickness increase, the sheet resistance of OSCs also increased and the transmittance was decreased consequently the efficiency of OSCs were decreased. If, the OSCs can be increased of PCE, after optimized the large area fabrication. The proposed spray technique can be available for low-coas, large area OSCs fabrication processes.