원형 탈모 환자 222명의 한의학적 치료 효과에 대한 후향적 연구 = Retrospective Study about the Effectiveness of Korean Medical Treatment on 222 Patients with Alopecia Areata

다국어 초록 (Multilingual Abstract)

Objectives : The purpose of this study is to report the effectiveness of Korean medical treatment on 222 patients with alopecia areata.
Methods : The subjects of this study were 222 patients who had received Korean medical treatment among the patients who visited the Balmer’s Korean Medicine Clinic from January 1, 2016 to December 31, 2017. The extent of the alopecia areata was measured every month to determine the improvement. We analyzed the relationship between the types of alopecia areata, the extent of hair loss, duration of illness, age at first visit, and the treatment of alopecia areata.
Results : 1. There were 100 males(45.0%) and 122 females(55.0%). The mean age of patients was 35.3 years old.
2. Of the 222 patients, 142(64%) were “cured”. 31(14%) showed “good”, 21(9.5%) showed “fair”, 28(12.6%) showed “poor” improvement.
3. According to clinical records, of the 64 patients with alopecia areata(AA), 48(75.0%) were cured. Of the 100 patients with alopecia areata multiplex(AAM), 68 patients (68.0%), 12(50.0%) out of 24 patients with ophiasis, 5(55.6%) out of 9 with alopecia semi-totalis(AST), 3(50.0%) out of 6 patients with alopecia totalis(AT), 6(31.6%) out of 19 patients with alopecia universalis(AU) were cured.
4. Patients with the wider hair loss extent and with more severe type of alopecia areata required longer treatment period to cure, and the cure rate was lowered(p<0.05).
5. The shorter duration of the disease was related to the higher cure rate(p<0.05). If the treatment was started after six months of the duration, the cure rate was lowered. Therefore, beginning treatment within six months of the onset is recommended.
6. The period until terminal hair showed was 1.5 months for AA, 1.7 months for AAM, 1.6 months for ophiasis, 1.9 months for AST, 2.3 months for AT, 3.2 months for AU.
7. The treatment period to cure was 4.9 months for AA, 7.3 months for AAM, 7.7 months for ophiasis, 6.8 months for AST, 7.7 months for AT, 16.3 months for AU.
8. The major prognostic factors were extent and type of alopecia, duration of the disease and relapse.
Conclusions : We analyzed the effectiveness of Korean medical treatment through cure rate according to the prognostic factors. This study will provide useful data for the treatment of alopecia areata.

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