Pharmacological studies on Shihogesikungang-Tang water extract were conducted. Analgesic activity as evaluated by writhing syndrome in mice was noted. A decrease in spontaneus movement, muscle relaxant activity and a prolongation of duration of thiope...
Pharmacological studies on Shihogesikungang-Tang water extract were conducted. Analgesic activity as evaluated by writhing syndrome in mice was noted. A decrease in spontaneus movement, muscle relaxant activity and a prolongation of duration of thiopental-induced sleep were significantly shown in mice. An antipyretic activity in endotoxin febrile rats was recognized. Antiinflammatory activity in carrageenin-induced edema in rats was significantly noted. Negative inotropic action on isolated frog heart, vasodilative action in rabbit peripheral blood vessel and hypotension in anesthetized rabbit were remarkably recognized.