레이저절제술을 받은 조기성문암 환자의 음성평가 = Voice Evaluation after Laser Resection of Early Glottic Cancer

다국어 초록 (Multilingual Abstract)

Voice quality may be an important issue for choosing treatment options of early glottic cancer. It has
been reported that voice quality is worse after laser cordectomy compared to that of radiation therapy. But, with developed visualization
tools, the precise localization of lesions became possible enabling surgeons to decide the appropriate surgical extent to preserve
voice after laser cordectomy. The authors assessed the postoperative voice quality of patients who underwent laser cordectomy according
to the classification by the European Laryngological Society. Subjects and Method：Thirty patients who were diagnosed with
glottic cancer and treated with laser cordectomy between April, 1999 and January, 2006, were evaluated. All the patients were
followed-up more than 6 months. Objective evaluations included maximal phonation time, fundamental frequency, jitter, shimmer,
noise-to-harmonics ratio and subjective evaluation was performed by the GRBAS scale. Results：The type II laser cordectomy group
and some cases of the type III cordectomy showed no significant differences compared with the normal control group in both objective
and subjective evaluations. Conclusion：This study shows that the group of laser cordectomy type II and some cases of type III
had acceptable results compared to that of the normal control group. Thus, laser cordectomy could be considered as an alternative
to radiation therapy in selected patients with early glottic cancer, even when preserving the quality of voice is an important issue.
(Korean J Otorhinolaryngol-Head Neck Surg 2008;51:250-5)

참고문헌 (Reference)

1 Wedman J, "Voice results in patients with T1a glottic cancer treated by radiotherapy or endoscopic measures" 259 (259): 547-550, 2002

2 Krengli M, "Voice quality after treatment for T1a glottic carcinoma-radiotherapy versus laser cordectomy" 43 (43): 284-289, 2004

3 Hocevar-Boltezar I, "Voice quality after radiation therapy for early glottic cancer" 126 (126): 1097-1100, 2000

4 Rydell R, "Voice evaluation before and after laser excision vs. radiotherapy of T1A glottic carcinoma" 115 (115): 560-565, 1995

5 Peretti G, "Vocal outcome after endoscopic cordectomies for Tis and T1 glottic carcinomas" 112 (112): 174-179, 2003

6 Hirano M, "Vocal function following carbon dioxide laser surgery for glottic carcinoma" 94 (94): 232-235, 1985

7 Haddad L, "Vocal assessment in patients submited to CO2 laser cordectomy" 72 (72): 295-301, 2006

8 Bless DM, "Videostroboscopic evaluation of the larynx" 66 (66): 289-296, 1987

9 Karim AB, "The quality of voice in patients irradiated for laryngeal carcinoma" 51 (51): 47-49, 1983

10 Mendenhall WM, "T1- T2 vocal cord carcinoma: A basis for comparing the results of radiotherapy and surgery" 10 (10): 373-377, 1988

11 Epstein BE, "Stage T1 glottic carcinoma: Results of radiation therapy or laser excision" 175 (175): 567-570, 1990

12 Rudoltz MS, "Prognostic factors for local control and survival in T1 squamous cell carcinoma of the glottis" 26 (26): 767-772, 1993

13 Zeitels SM, "Premalignant epithelium and microinvasive cancer of the vocal fold: The evolution of phonomicrosurgical management" 105 (105): 1-51, 1995

14 Verdonck-de Leeuw IM, "Multidimensional assessment of voice characteristics after radiotherapy for early glottic cancer" 109 (109): 241-248, 1999

15 Ledda GP, "Functional outcomes after CO2 laser treatment of early glottic carcinoma" 116 (116): 1007-1011, 2006

16 Benninger MS, "Factors associated with recurrence and voice quality following radiation therapy for T1 and T2 glottic carcinomas" 104 (104): 294-298, 1994

17 Remacle M, "Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society" 257 (257): 227-231, 2000

18 Rosier JF, "Comparison of external radiotherapy, laser microsurgery and partial laryngectomy for the treatment of T1N0M0 glottic carcinomas: A retrospective evaluation" 48 (48): 175-183, 1998

19 McGuirt WF, "Comparative voice results after laser resection or irradiation of T1 vocal cord carcinoma" 120 (120): 951-955, 1994

20 Lehman JJ, "An objective assessment of voice production after radiation therapy for stage I squamous cell carcinoma of the glottis" 98 (98): 121-129, 1988