Thoracic Chordoma Misdiagnosed as Primary Adenocarcinoma of the Mediastinum

다국어 초록 (Multilingual Abstract)

Chordoma is a rare malignant bone tumor originating from the embryonic notochord. Herein, we present a case of thoracic chordoma located at T3–T5 that was misdiagnosed as primary mediastinal adenocarcinoma. The patient underwent neoadjuvant chemoradia- tion and the disease showed little response. Due to vertebral body invasion, we performed en bloc mass removal and partial corpectomy (T4–5) in collaboration with orthopedic sur- geons.

참고문헌 (Reference)

1 이승훈, "후종격동 종양으로 나타난 척삭종(Chordoma) 1예" 대한흉부외과학회 36 (36): 707-710, 2003

2 Kim S, "Resection of a posterior mediastinal mass : lessons learned from a failed exploration for presumed schwannoma" 152 : e75-e77, 2016

3 Rahman AM, "Giant mediastinal chordoma" 73 : 1952-1954, 2002

4 Ottavio Rena, "Giant Chordoma of the Upper Thoracic Spine with Mediastinal Involvement: A Surgical Challenge" 대한척추외과학회 8 (8): 353-356, 2014

5 Maesen F, "Chordoma of the thorax" 68 : 68-72, 1986

6 Bakker SH, "Chordoma : a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival" 27 : 3043-3058, 2018

7 Rosenberg AE, "Chondroid chordoma : a variant of chordoma : a morphologic and immunohistochemical study" 101 : 36-41, 1994

8 Stacchiotti S, "Building a global consensus approach to chordoma: a position paper from the medical and patient community" 16 : e71-e83, 2015