조기파막 환자의 혈중 중 , Esstadiol-17B 및 Progesterone치의 동태에 관한 연구 = Maternal Copper, Estradiol-17B and Progesterone Levels in Patients at Term with and without Premature Rupture of Membrances

다국어 초록 (Multilingual Abstract)

Premature rupture of membrances is very important because of its association with prematurity cord prolapse, chorioamnionitis high prenatal mortality and at times serious maternal morbidity. The purpose of this study is to measure the serum copper, estradiol-17B and progesterone levels in patients with and without premature rupture of membranes and to evaluate the relationship between copper, steriod hormone and premature rupture of membranes. The results of the study are as follows; 1. serum copper levels in patients with PROM at term range from 204.6 to 281.4 ug/100ml with a mean+-S.E.M of 241.3+-22.3ug/100ml, whereas in the corresponding control group of normal term pregnancy from 224.9 to 299.9ug/100ml with a mean+-S.E.M of 255.1+-19.2ug/100ml. serum copper levels in patients with PROM significantly lower than in those with control group. 2. Concentration of serum estradiol-17B and progesterone in patients with PROM range from 14.36 to 36.88ng/ml with a mean +-S.E.M of 25.88+-7.00ng/ml and from 90.60 to 191.00ng/ml with a mean +-S.E.M of 141.40+-25.95ng/ml respectively, whereas in corresponding control group range from 15.04 to 44.16ng/ml with a mean +- S.E.M of 30.12+-7.93ng/ml respectively. serum estadiol-17B and progesterone levels are significantly lower in patients with PROM at term as compared with a control group. 3. There is little significant relationship between copper and steroid hormone in both group.