골수흡인물 농축액 및 기질유래연골형성 수술 이후 관찰된 거골의 골연골병변의 골유합: 증례 보고 = Bony Union of Osteochondral Lesion of the Talus after Bone Marrow Aspirate Concentrate and Matrix-Induced Chondrogenesis: A Case Report

다국어 초록 (Multilingual Abstract)

Traditionally, arthroscopic microfracture and autologous osteochondral autograft transplantation have been the primary surgical treat- ments for osteochondral lesions of the talus. On the other hand, recent advancements have introduced alternative approaches, such as autologous chondrocyte transplantation, matrix-derived autologous chondrocyte transplantation, intra-articular injection of concen- trated bone marrow aspirate concentrate, and the use of fibrin glue to address chondral defects. Furthermore, some studies have ex- plored a combination of bone marrow aspirate and matrix-derived chondrogenesis. In light of these developments, this report presents a case study of a young male patient in his early twenties with a relatively large osteochondral lesion exceeding 1.5 cm2 on the medial talar dome. Instead of removing the osteochondral lesion, a surgical approach was employed to retain the lesion while addressing the unstable cartilage in the affected area. This approach involved a combination of bone marrow aspirate concentrate and matrix-derived chondro- genesis. The treatment yielded favorable clinical outcomes and ultimately successfully induced the bony union of osteochondral lesions.
This paper reports the author’s experience with this innovative approach with a review of the relevant literature