Covalent Modification of Cellulosic-based Textiles: A New Strategy to Obtain Antimicrobial Properties

다국어 초록 (Multilingual Abstract)

In the past years the textile industry haswitnessed new advances in the area of textile fiber chainsengineering, which allow the modification of the structureof such chains so as to produce polymers responsive tochanges in the environment, thus capable of attaching tocells and bioactive molecules. On the other hand, followingour society's trend towards higher hygiene standards, theresearch and development of antimicrobial textiles hasshown a remarkable increase. Applications of such textilescan nowadays be found in underwear, sportswear, homefurnishing, protective clothing, wound-dressings and inmicrobial infection high risk settings, such as health careinstitutions. The present research aims at the developmentof a strong, durable and washable antimicrobial L-Cysteine(L-Cys)-functionalized cotton by means of a covalentmechanism. The covalent binding of L-Cys onto cellulosicfibers was assessed by Scanning Electron Microscopy-Energy Dispersive X-ray Spectroscopy (SEM-EDS) andFourier Transform Infrared Spectroscopy (FTIR) analysis.
Antimicrobial assays showed that the functionalized cottonyielded strong microbial killing rates, exhibiting inhibitionratios of 89 and 83% against K. pneumoniae and S. aureus,respectively. These results demonstrate the effectiveness ofthe covalent modification of cotton fabrics with L-Cysadding antimicrobial properties to cotton fibers and thusopen the door to a world of applications in the area ofincreased risk microbial infections.

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