Gradual Increase in Hematologic Malignancy in Korea from 2005 to 2015 Based on the National Health Insurance Service Data

다국어 초록 (Multilingual Abstract)

Background: Hematologic malignancies have a relatively lower prevalence than major solid cancers, although the incidence of hematologic malignancies has significantly increased in recent years. However, understanding the current status of hematologic malignancy is significantly challenging because basic data regarding this malignancy are insufficient in the Korean population. Methods: From 2005 to 2015, the status of seven codes of hematologic malignancy, containing 24 subcodes defined using a classification defined by the Korean Classification of Disease-6, was analyzed. The number of new patients, crude incidence rate, prevalence rate, and age-standardized incidence rate were also investigated. Results were analyzed based on National Health Insurance Service (NHIS) data. Results: The number of new patients showed an overall increase over time and a rate of increase up to 56.7% for 10 years. The number of male patients was higher than that of female patients, with the majority of patients aged greater than 60 years. The incidence and prevalence rates have increased steadily. Conclusions: Consistent with the previous studies, this study might be useful to understand the current status of hematologic malignancy and might contribute to the improvement of national public healthcare.

참고문헌 (Reference)

1 Hasserjian RP, "WHO classification of tumours of haematopoietic and lymphoid tissues" International Agency for Research on Cancer 98-120, 2017

2 Hyeon Jin Park, "Statistics of hematologic malignancies in Korea: incidence, prevalence and survival rates from 1999 to 2008" 대한혈액학회 47 (47): 28-38, 2012

3 Noone AM, "SEER Cancer Statistics Review, 1975-2015"

4 Eun-Hye Park, "Nationwide statistical analysis of myeloid malignancies in Korea: incidence and survival rate from 1999 to 2012" 대한혈액학회 50 (50): 204-217, 2015

5 이혜원, "Nationwide Statistical Analysis of Lymphoid Malignancies in Korea" 대한암학회 50 (50): 222-238, 2018

6 Montalban-Bravo G, "Myelodysplastic syndromes : 2018 update on diagnosis, risk-stratification and management" 93 : 129-147, 2018

7 Statistics Korea, "Korean Standard Classification of Diseases and Causes of Death(KCD-6)" Statistics Korea 2011

8 Chihara D, "Incidence of myelodysplastic syndrome in Japan" 24 : 469-473, 2014

9 Sant M, "Incidence of hematologic malignancies in Europe by morphologic subtype : results of the HAEMACARE project" 116 : 3724-3734, 2010

10 송태양, "Improvement of treatment outcome over 2 decades in children with acute myeloid leukemia" 대한혈액학회 53 (53): 25-34, 2018

11 Li J, "Estimating the prevalence of hematological malignancies and precursor conditions using data from Haematological Malignancy Research Network(HMRN)" 27 : 1019-1026, 2016

12 Korea Central Cancer Registry and National Cancer Center, "Annual report of cancer statistics in Korea in 2015" Ministry of Health and Welfare 2017

13 Terwilliger T, "Acute lymphoblastic leukemia : a comprehensive review and 2017 update" 7 : e577-, 2017