RISS 검색 - 국내학술지논문 상세보기

다국어 초록 (Multilingual Abstract)

Purpose: This study evaluated differences and shifting patterns in the health-related quality of life (HRQoL) of 5-year gastric cancer survivors after either a distal subtotal gastrectomy (DSG) or total gastrectomy (TG).
Materials and Methods: We analyzed the prospectively collected HRQoL data of 528 patients who survived 5 years without recurrence using the European Organization for the Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire and the EORTC Quality of Life Questionnaire-Stomach module according to the type of surgery. The purpose was to identify the proportion of patients with deteriorating HRQoL and to assess the clinical significance of these changes.
Results: Deteriorating HRQoL was prevalent in both groups, including a large proportion of the DSG group. Decreased overall health status and scores on several function scales were less in the DSG group, while increases on the symptom scales were higher in the TG group. For most of the scales, gaps in HRQoL during the early postoperative period did not merge within the 5 years. Scores on the diarrhea and body image scales revealed “moderate changes” in both groups.
Conclusions: During the 5-year period after surgery, the TG group suffered from inferior HRQoL compared to the DSG group. However, a large proportion of the DSG group also suffered HRQoL deterioration. In general, the TG group experienced more HRQoL decline, with diarrhea and body image being the major concerns for both groups. To improve HRQoL after gastrectomy, patients must be better informed about post-gastrectomy symptoms. These symptoms must be vigorously investigated, and medical interventions should be available parallel to nutritional support. Favorable evidence of function-preserving gastrectomy should be established and disseminated to improve the HRQoL of early gastric cancer patients.

참고문헌 (Reference)

1 Climent M, "Weight loss and quality of life in patients surviving 2 years after gastric cancer resection" 43 : 1337-1343, 2017

2 Yun YH, "Validation of the Korean version of the EORTC QLQ-C30" 13 : 863-868, 2004

3 An JY, "The difficult choice between total and proximal gastrectomy in proximal early gastric cancer" 196 : 587-591, 2008

4 Maruyama K, "Surgical treatment of gastric cancer in Japan, trend from standardization to individualization" 109 : 722-730, 2014

5 박수진, "Serial Comparisons of Quality of Life after Distal Subtotal or Total Gastrectomy: What Are the Rational Approaches for Quality of Life Management?" 대한위암학회 14 (14): 32-38, 2014

6 Tyrväinen T, "Quality of life in the long-term survivors after total gastrectomy for gastric carcinoma" 97 : 121-124, 2008

7 Lee SS, "Quality of life in cancer survivors 5 years or more after total gastrectomy : a case-control study" 12 : 700-705, 2014

8 Lee SS, "Quality of life beyond the early postoperative period after laparoscopy-assisted distal gastrectomy : the level of patient expectation as the essence of quality of life" 15 : 299-304, 2012

9 Takahashi M, "Quality of life after total vs distal gastrectomy with Roux-en-Y reconstruction : use of the Postgastrectomy Syndrome Assessment Scale-45" 23 : 2068-2076, 2017

10 Goh YM, "Quality of life after total and subtotal gastrectomy for gastric carcinoma" 13 : 267-270, 2015