Double-sided electrohydrodynamic jet printing of two-dimensional electrode array in paper-based digital microfluidics

다국어 초록 (Multilingual Abstract)

<P><B>Abstract</B></P> <P>Double-sided electrohydrodynamic jet printing of circuitry using silver nanowires (AgNWs) and dispensing of high viscosity silver nanoparticles (AgNPs) is demonstrated for the first time in the fabrication of a two-dimensional array of electrodes (3D circuitry) on a single sheet of paper. The penetration of AgNW ink through the paper’s thickness by capillary imbibition allows for multilayer electrical access to connect the individual electrodes. This makes it an automated and efficient choice as the functional area of the device is conserved and the surface of the paper is preserved. This allows for two-dimensional droplet manipulation on a paper-based digital microfluidics (PBDMF) platform. Compared to printed circuit board technology, paper-based electronics offer a range of desirable properties: they are light weight, portable, economical, flexible, biodegradable, and the materials are abundantly available. The fabricated PBDMF chip is demonstrated to be a low-cost, fully reconfigurable, and disposable point-of-care diagnostic platform for the environmental sensing of pesticide using organophosphorus hydrolase enzyme through colorimetric detection via smartphone.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Silver nanowires penetrated through paper’s thickness for making 3D interconnects. </LI> <LI> High viscosity silver nanoparticles dispensed on paper reveal no penetration. </LI> <LI> 3D circuitry in single sheet of paper printed using double-sided EHD jet printing. </LI> <LI> Two-dimensional droplet actuation achieved on a paper-based digital microfluidics. </LI> <LI> Cellphone-based colorimetric detection of methyl paraoxon from 10 to 100 μM concentration. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>