직업성 질환에서 유전적인 영향 = Genetic Effects in Occupational Disease

다국어 초록 (Multilingual Abstract)

The differences in disease occurrence varies from country to country. These might be either due to difference in genetic constituency in individuals from different ethnic backgrounds or to environmental factors including diet and personal habits, or more plausibly to the interactive effects of genetic and environmental factors. Post-gencomic era opens the potential application of functional genomics to the fields of occupational health. This mini-review of $quot;genetic effects in occupational diseases$quot; deals with several newly challenging areas of application of genetic information in occupational health Recent reports regarding the genetic susceptibility to occupational asthma, particularly DRB1 or DQB1 HLA class polymorphism give us interesting insights that the genetic information may play an important role in development of occupational asthma and this can be a good example of how genetic information provide us to better understanding for etiology of occupational diseases. Genetic testing for the employees who apply new jobs or genetic monitoring for the employees in certain hazardous environments also stimulate important issues of ethical, social, and economical problems among employees enforced to take the genetic testing. Finally, how genetic information can be used in delineating work-relatedness in compensating cases for occupational diseases was reviewed.

목차 (Table of Contents)

• 1.머 리 말
• 1.직업성 질환에서 생체지표의 이용
• 2.유해인자 허용기준과 생물학적 모니터링에서 유전 정보의 이용
• 3.신체 검사시 유전자 검사의 이용과 문제점
• 4.직업병 판정