The differences in disease occurrence varies from country to country. These might be either due to difference in genetic constituency in individuals from different ethnic backgrounds or to environmental factors including diet and personal habits, or m...
The differences in disease occurrence varies from country to country. These might be either due to difference in genetic constituency in individuals from different ethnic backgrounds or to environmental factors including diet and personal habits, or more plausibly to the interactive effects of genetic and environmental factors. Post-gencomic era opens the potential application of functional genomics to the fields of occupational health. This mini-review of $quot;genetic effects in occupational diseases$quot; deals with several newly challenging areas of application of genetic information in occupational health Recent reports regarding the genetic susceptibility to occupational asthma, particularly DRB1 or DQB1 HLA class polymorphism give us interesting insights that the genetic information may play an important role in development of occupational asthma and this can be a good example of how genetic information provide us to better understanding for etiology of occupational diseases. Genetic testing for the employees who apply new jobs or genetic monitoring for the employees in certain hazardous environments also stimulate important issues of ethical, social, and economical problems among employees enforced to take the genetic testing. Finally, how genetic information can be used in delineating work-relatedness in compensating cases for occupational diseases was reviewed.