<P>Complementary metal oxide semiconductor (CMOS) image sensors have been used previously in the analysis of biological samples. In the present study, a CMOS image sensor was used to monitor the concentration of oxidized mouse plasma glucose (86...
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https://www.riss.kr/link?id=A107672100
2013
-
SCOPUS,SCIE
학술저널
5679-5684(6쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>Complementary metal oxide semiconductor (CMOS) image sensors have been used previously in the analysis of biological samples. In the present study, a CMOS image sensor was used to monitor the concentration of oxidized mouse plasma glucose (86...
<P>Complementary metal oxide semiconductor (CMOS) image sensors have been used previously in the analysis of biological samples. In the present study, a CMOS image sensor was used to monitor the concentration of oxidized mouse plasma glucose (86–322 mg dL<SUP>−1</SUP>) based on photon count variation. Measurement of the concentration of oxidized glucose was dependent on changes in color intensity; color intensity increased with increasing glucose concentration. The high color density of glucose highly prevented photons from passing through the polydimethylsiloxane (PDMS) chip, which suggests that the photon count was altered by color intensity. Photons were detected by a photodiode in the CMOS image sensor and converted to digital numbers by an analog to digital converter (ADC). Additionally, UV-spectral analysis and time-dependent photon analysis proved the efficiency of the detection system. This simple, effective, and consistent method for glucose measurement shows that CMOS image sensors are efficient devices for monitoring glucose in point-of-care applications.</P>
<P>Graphic Abstract</P><P>The complementary metal oxide semiconductor image sensor is an efficient platform for glucose monitoring.
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Multilayered nano-prism vertex tips for tip-enhanced Raman spectroscopy and imaging