Malignant Melanoma of Anorectum: Two Case Reports

다국어 초록 (Multilingual Abstract)

Malignant melanoma of the anorectum is a rare disorder. Patients often present with local symptoms similar to benign diseases. The prognosis is very poor, and almost all patients die because of metastases. We report 2 female patients with unremarkable histories. Both of them received previous operations before visiting our center after they were diagnosed with anorectal malignant melanoma. One case underwent abdominoperineal resection and postoperative chemotherapy. The other had been treated with ultralow anterior resection followed by immunotherapy.

참고문헌 (Reference)

1 Malik A, "What is the best surgical treatment for anorectal melanoma?" 19 : 121-123, 2004

2 Morton DL, "Validation of the accuracy of intraoperative lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: a multicenter trial. Multicenter Selective Lymphadenectomy Trial Group" 230 : 453-463, 1999

3 Yeh JJ, "The role of abdominoperineal resection as surgical therapy for anorectal melanoma" 244 : 1012-1017, 2006

4 Chang AE, "The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society" 83 : 1664-1678, 1998

5 Tien HY, "Sentinel lymph node metastasis in anal melanoma: a case report" 32 : 53-56, 2002

6 Coté TR, "Primary melanomas of the esophagus and anorectum: epidemiologic comparison with melanoma of the skin" 19 : 58-60, 2009

7 Kim KW, "Primary malignant melanoma of the rectum: CT findings in eight patients" 232 : 181-186, 2004

8 Ragnarsson-Olding BK, "Primary ano-rectal malignant melanomas within a population-based national patient series in Sweden during 40 years" 48 : 125-131, 2009

9 Iddings DM, "Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients?" 17 : 40-44, 2010

10 Prichard RS, "Positron emission tomography for staging and management of malignant melanoma" 89 : 389-396, 2002

11 Chapman PB, "Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma" 17 : 2745-2751, 1999

12 Schachter J, "Pembrolizumab versus ipilimumab for advanced melanoma:final overall survival results of a multicentre, randomised, openlabel phase 3 study (KEYNOTE-006)" 390 : 1853-1862, 2017

13 Banerjee SS, "Morphological and immunophenotypic variations in malignant melanoma" 36 : 387-402, 2000

14 van’t Riet M, "Melanoma of the anus disguised as hemorrhoids: surgical management illustrated by a case report" 52 : 1745-1747, 2007

15 Nilsson PJ, "Importance of clear resection margins in anorectal malignant melanoma" 97 : 98-103, 2010

16 Zhang S, "Effect of misdiagnosis on the prognosis of anorectal malignant melanoma" 136 : 1401-1405, 2010

17 Wilson MA, "Chemotherapy for melanoma" 167 : 209-229, 2016

18 Cagir B, "Changing epidemiology of anorectal melanoma" 42 : 1203-1208, 1999

19 Slingluff CI Jr, "Cancer: principles and practice of oncology" Lippincott Williams & Wilkins 1643-1691, 2011

20 Brady MS, "Anorectal melanoma. A 64-year experience at Memorial Sloan-Kettering Cancer Center" 38 : 146-151, 1995

21 Chute DJ, "Anorectal malignant melanoma:morphologic and immunohistochemical features" 126 : 93-100, 2006

22 Arakawa K, "A case report of anorectal malignant melanoma with mucosal skipped lesion" 24 : 206-210, 2016