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      SCOPUS SCIE

      Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents

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      https://www.riss.kr/link?id=A107571849

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      <P>Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycle <I>via</I> apoptosis.</P> <P>Graphic Abstract</P><P>Two novel molecular prismatic cages were prepared <I>via</I> the self-assembly of a tripodal donor with metallic acceptors and their antitumor activity was screened against various cancer cell lines. The cytotoxicity of nano cage 8 was found to be considerably stronger than that of cisplatin.
      <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cc10167f'>
      </P>
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      <P>Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited t...

      <P>Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycle <I>via</I> apoptosis.</P> <P>Graphic Abstract</P><P>Two novel molecular prismatic cages were prepared <I>via</I> the self-assembly of a tripodal donor with metallic acceptors and their antitumor activity was screened against various cancer cell lines. The cytotoxicity of nano cage 8 was found to be considerably stronger than that of cisplatin.
      <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cc10167f'>
      </P>

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