Spatial Allocation and Specification of Cardiomyocytes during Zebrafish Embryogenesis

다국어 초록 (Multilingual Abstract)

Incomplete development and severe malformation of the heart result in miscarriage of embryos because of its malfunction as a pump for circulation. During cardiogenesis, development of the heart is precisely coordinated by the genetically-primed program that is revealed by the sequential expression of transcription factors. It is important to investigate how spatial allocation of the heart containing cardiomyocytes and other mesoderm-derived cells is determined. In addition, the molecular mechanism underlying cardiomyocyte differentiation still remains elusive. The location of ectoderm-, mesoderm-, and endoderm-derived organs is determined by their initial allocation and subsequent mutual cell-cell interactions or paracrine-based regulation. In the present work, we provide an overview of cardiac development controlled by the germ layers and discuss the points that should be uncovered in future for understanding cardiogenesis.

참고문헌 (Reference)

1 Guner-Ataman B, "Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function" 140 : 1353-1363, 2013

2 Liu J, "Zebrafish in the study of early cardiac development" 110 : 870-874, 2012

3 McCulley DJ, "Transcription factor pathways and congenital heart disease" 100 : 253-277, 2012

4 Driever W, "The zebrafish: heritable disorders in transparent embryos" 97 : 1788-1794, 1996

5 Long S, "The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry" 130 : 2303-2316, 2003

6 Begemann G, "The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain" 128 : 3081-3094, 2001

7 Roxo-Rosa M, "The zebrafish Kupffer’s vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR" 4 : 1356-1366, 2015

8 Sakaguchi T, "The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish" 133 : 4063-4072, 2006

9 Osborne N, "The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish" 18 : 1882-1888, 2008

10 Kawahara A, "The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors" 323 : 524-527, 2009

11 Pennekamp P, "The ion channel polycystin-2 is required for left-right axis determination in mice" 12 : 938-943, 2002

12 Hoffman JI, "The incidence of congenital heart disease" 39 : 1890-1900, 2002

13 Patton EE, "The art and design of genetic screens: zebrafish" 2 : 956-966, 2001

14 Amack JD, "The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry" 14 : 685-690, 2004

15 Mendelson K, "Sphingosine 1-phosphate signalling" 141 : 5-9, 2014

16 Clay H, "Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development" 418 : 157-165, 2016

17 D’Amico LA, "Spatially distinct domains of cell behavior in the zebrafish organizer region" 75 : 563-577, 1997

18 Lahvic JL, "Small heat shock proteins are necessary for heart migration and laterality determination in zebrafish" 384 : 166-180, 2013

19 Mizoguchi T, "Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation" 135 : 2521-2529, 2008

20 Fukui H, "S1PYap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish" 31 : 128-136, 2014

21 Rao DR, "Role of cilia in structural birth defects: insights from ciliopathy mutant mouse models" 102 : 115-125, 2014

22 Keegan BR, "Retinoic acid signaling restricts the cardiac progenitor pool" 307 : 247-249, 2005

23 Marques SR, "Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart" 321 : 397-406, 2008

24 Knowles MR, "Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease" 188 : 913-922, 2013

25 Delling M, "Primary cilia are not calciumresponsive mechanosensors" 531 : 656-660, 2016

26 Keegan BR, "Organization of cardiac chamber progenitors in the zebrafish blastula" 131 : 3081-3091, 2004

27 Tong YF, "Mutations of NKX2.5 and GATA4 genes in the development of congenital heart disease" 588 : 86-94, 2016

28 Schier AF, "Molecular genetics of axis formation in zebrafish" 39 : 561-613, 2005

29 Lazic S, "Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish" 354 : 123-133, 2011

30 Xiang SY, "Lysophospholipid receptor activation of RhoA and lipid signaling pathways" 1831 : 213-222, 2013

31 Ramsdell AF, "Left-right asymmetry and congenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination" 288 : 1-20, 2005

32 Zhou Y, "Latent TGF-beta binding protein 3 identifies a second heart field in zebrafish" 474 : 645-648, 2011

33 Essner JJ, "Kupffer’s vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut" 132 : 1247-1260, 2005

34 Yuan S, "Intraciliary calcium oscillations initiate vertebrate left-right asymmetry" 25 : 556-567, 2015

35 Sarmah B, "Inositol polyphosphates regulate zebrafish left-right asymmetry" 9 : 133-145, 2005

36 Wilcox AJ, "Incidence of early loss of pregnancy" 319 : 189-194, 1988

37 Santoriello C, "Hooked! Modeling human disease in zebrafish" 122 : 2337-2343, 2012

38 Chen JN, "Genetics of heart development" 16 : 383-388, 2000

39 Reiter JF, "Gata5 is required for the development of the heart and endoderm in zebrafish" 13 : 2983-2995, 1999

40 Okabe N, "Fluid dynamics in zebrafish Kupffer’s vesicle" 237 : 3602-3612, 2008

41 Tanaka Y, "FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination" 435 : 172-177, 2005

42 Neugebauer JM, "FGF signalling during embryo development regulates cilia length in diverse epithelia" 458 : 651-654, 2009

43 Regan L, Rai R, "Epidemiology and the medical causes of miscarriage" 14 : 839-854, 2000

44 Marques SR, "Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality" 328 : 472-482, 2009

45 Kennedy MP, "Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia" 115 : 2814-2821, 2007

46 Kramer-Zucker AG, "Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer’s vesicle is required for normal organogenesis" 132 : 1907-1921, 2005

47 McGrath J, "Cilia are at the heart of vertebrate left-right asymmetry" 13 : 385-392, 2003

48 Matsui T, "Cell collectivity regulation within migrating cell cluster during Kupffer’s vesicle formation in zebrafish" 3 : 27-, 2015

49 Kikuchi Y, "Casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish" 15 : 1493-1505, 2001

50 Moller JH, "Cardiovascular health and disease in children: current status. A Special Writing Group from the Task Force on Children and Youth, American Heart Association" 89 : 923-930, 1994

51 Stainier DY, "Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formation" 119 : 31-40, 1993

52 Yelon D, "Cardiac patterning and morphogenesis in zebrafish" 222 : 552-563, 2001

53 Rottbauer W, "Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart" 99 : 323-331, 2006

54 Matsui T, "Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer’s vesicle organogenesis" 108 : 9881-9886, 2011

55 Auer TO, "CRISPR/Cas9 and TALEN-mediated knock-in approaches in zebrafish" 69 : 142-150, 2014

56 Reiter JF, "Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5" 234 : 330-338, 2001

57 Ueno S, "Biphasic role for Wnt/betacatenin signaling in cardiac specification in zebrafish and embryonic stem cells" 104 : 9685-9690, 2007

58 Takao D, "Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left-right axis formation" 376 : 23-30, 2013

59 Zeng XX, "Apelin and its receptor control heart field formation during zebrafish gastrulation" 12 : 391-402, 2007

60 Kupperman E, "A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development" 406 : 192-195, 2000

61 Dickmeis T, "A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene" 15 : 1487-1492, 2001