Reductive Acetylation of Carbonyl Compounds to Acetates with Pyridine Zinc Borohydride

다국어 초록 (Multilingual Abstract)

Reductive acetylation of a variety of carbonyl compounds such as aldehydes, ketones and a,b-unsaturated enals/enones was carried out efficiently with pyridine zinc borohydride, (Py)Zn(BH4)2, in a mixture of THF-EtOAc at room temperature or under reflux condition. The corresponding acetates were obtained in high to excellent yields. In addition, chemoselective reductive acetylation of aldehydes over ketones was achieved perfectly with the reagent at room temperature.

참고문헌 (Reference)

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