1 Shaw RJ, "The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress" 101 : 3329-3335, 2004
2 Marsin AS, "The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase" 277 : 30778-30783, 2002
3 Jung CH, "Syzygium aromaticum ethanol extract reduces high-fat diet-induced obesity in mice through downregulation of adipogenic and lipogenic gene expression" 4 : 409-414, 2012
4 Yeh GY, "Systematic review of herbs and dietary supplements for glycemic control in diabetes" 26 : 1277-1294, 2003
5 Tu Z, "Subdomain VIII is a specificity-determining region in MEKK1" 278 : 48498-48505, 2003
6 Price Nathan L, "SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function" 15 : 675-690, 2012
7 Sun C, "SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B" 6 : 307-319, 2007
8 Tu Z, "Rosemary (Rosmarinus officinalis L.) extract regulates glucose and lipid metabolism by activating AMPK and PPAR pathways in HepG2 Cells" 61 : 2803-2810, 2013
9 Zhou G, "Role of AMP-activated protein kinase in mechanism of metformin action" 108 : 1167-1174, 2001
10 Lagouge M, "Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha" 127 : 1109-1122, 2006
1 Shaw RJ, "The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress" 101 : 3329-3335, 2004
2 Marsin AS, "The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase" 277 : 30778-30783, 2002
3 Jung CH, "Syzygium aromaticum ethanol extract reduces high-fat diet-induced obesity in mice through downregulation of adipogenic and lipogenic gene expression" 4 : 409-414, 2012
4 Yeh GY, "Systematic review of herbs and dietary supplements for glycemic control in diabetes" 26 : 1277-1294, 2003
5 Tu Z, "Subdomain VIII is a specificity-determining region in MEKK1" 278 : 48498-48505, 2003
6 Price Nathan L, "SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function" 15 : 675-690, 2012
7 Sun C, "SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B" 6 : 307-319, 2007
8 Tu Z, "Rosemary (Rosmarinus officinalis L.) extract regulates glucose and lipid metabolism by activating AMPK and PPAR pathways in HepG2 Cells" 61 : 2803-2810, 2013
9 Zhou G, "Role of AMP-activated protein kinase in mechanism of metformin action" 108 : 1167-1174, 2001
10 Lagouge M, "Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha" 127 : 1109-1122, 2006
11 Marsin AS, "Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia" 10 : 1247-1255, 2000
12 Austin S, "PGC1a and mitochondrial metabolism–emerging concepts and relevance in ageing and neurodegenerative disorders" 125 : 4963-4971, 2012
13 Centers for Disease Control, "National diabetes fact sheet, national estimates and general information on diabetes and prediabetes in the United States" U.S. Department of Health and Human Services, Atlanta, GA, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention 2011
14 Kirpichnikov D, "Metformin, An Update" 137 : 25-33, 2002
15 Caton PW, "Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5" 205 : 97-106, 2010
16 Kim YD, "Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP" 57 : 306-314, 2008
17 Rahman S, "Mammalian Sirt1, insights on its biological functions" 9 : 11-, 2011
18 Ruderman NB, "Malonyl-CoA, fuel sensing, and insulin resistance" 276 : E1-E18, 1999
19 Lizcano JM, "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1" 23 : 833-843, 2004
20 Prabhakar PK, "Interaction of phytochemicals with hypoglycemic drugs on glucose uptake in L6 myotubes" 18 : 285-291, 2011
21 Tu Z, "IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression" 281 : 6699-6706, 2006
22 Kuroda M, "Hypoglycemic effects of clove(Syzygium aromaticum flower buds)on genetically diabetic KK-Ay mice and identification of the active ingredients" 66 : 394-399, 2012
23 McCloud TG, "High throughput extraction of plant, marine and fungal specimens for preservation of biologically active molecules" 15 : 4526-4563, 2010
24 Purushotham A, "Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation" 9 : 327-338, 2009
25 Raghavan S, "Handbook of Spices, Seasonings, and Flavorings" CRC Press 2007
26 Tennen RI, "Finding a target for resveratrol" 148 : 387-389, 2012
27 Stephanie Jew, "Evolution of the Human Diet: Linking Our Ancestral Diet to Modern Functional Foods as a Means of Chronic Disease Prevention" 한국식품영양과학회 12 (12): 925-934, 2009
28 Bahadoran Z, "Dietary polyphenols as potential nutraceuticals in management of diabetes, a review" 12 : 43-, 2013
29 American Diabetes Association, "Diagnosis and classification of diabetes mellitus" 33 : S62-S69, 2010
30 Ha J, "Critical phosphorylation sites for acetyl-CoA carboxylase activity" 269 : 22162-22168, 1994
31 Viswakarma N, "Coactivators in PPARregulated gene expression" 2010 : 250126-, 2010
32 Karmakar S, "Clove(Syzygium aromaticum Linn)extract rich in eugenol and eugenol derivatives shows bone-preserving efficacy" 26 : 500-509, 2012
33 Nassar MI, "Chemical constituents of clove (Syzygium aromaticum, Fam. Myrtaceae) and their antioxidant activity" 35 : 47-57, 2007
34 Hawley SA, "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase" 271 : 27879-27887, 1996
35 Peeters A, "Carbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK)activation, and peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) suppression" 286 : 42162-42179, 2011
36 Cefalu WT, "Botanicals and the metabolic syndrome" 87 : 481S-487S, 2008
37 Prasad RC, "An extract of Syzygium aromaticum represses genes encoding hepatic gluconeogenic enzymes" 96 : 295-301, 2005
38 Zhang BB, "An emerging drug target for diabetes and the metabolic syndrome" 9 : 407-416, 2009
39 Srinivasan S, "Ameliorating effect of eugenol on hyperglycemia by attenuating the key enzymes of glucose metabolism in streptozotocin-induced diabetic rats" 385 : 159-168, 2014
40 Canto C, "AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity" 458 : 1056-1060, 2009
41 Steinberg GR, "AMPK in health and disease" 89 : 1025-1078, 2009
42 Ruderman NB, "AMPK and SIRT1, a long-standing partnership?" 298 : E751-E760, 2010
43 Viollet B, "AMP-activated protein kinase in the regulation of hepatic energy metabolism, from physiology to therapeutic perspectives" 196 : 81-98, 2009
44 Singh S, "A database for anti-diabetic plants with clinical/experimental trials" 4 : 263-268, 2009
45 Corton JM, "5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?" 229 : 558-565, 1995