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      KCI등재 SCOPUS

      Computed Tomography Features of Follicular Thyroid Carcinoma: Comparison with Papillary Thyroid Carcinoma

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      https://www.riss.kr/link?id=A104530082

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      다국어 초록 (Multilingual Abstract)

      Purpose: The purpose of this study is to analyze the computed tomography (CT) features of follicular thyroid carcinoma (FTC) as compared to those of papillary thyroid carcinoma (PTC) to identify the characteristic imaging features of FTC.
      Materials and Methods: The following CT features were analyzed to compare FTCs (n = 17) and PTCs (n = 27): size, shape, margin, internal composition, calcification, enhancement homogeniety, extrathyroidal extension, lymph node (LN) metastasis and the density and degree of enhancement (qualitatively and quantitatively).
      Results: There were no significant differences between the patients with FTCs and those with PTCs with respect to age and gender, and the internal composition, calcification and enhancement homogeneity of the tumor. However, the FTCs tend to show a larger size (32 mm vs. 15 mm; respectively, p < 0.001), a round to oval shape (52.9% vs. 14.8% respectively, p = 0.001), a well-defined smooth margin (58.8% vs. 14.8% respectively, p = 0.009), less extrathyroidal extension (11.8% vs. 51.9% respectively, p = 0.007) and less LN metastasis (0% vs. 29.6% respectively, p = 0.016) compared to that of the PTCs. Furthermore, the FTCs showed significantly stronger enhancement in the early phase (146.4±42.4 vs. 98.5±38.2 respectively, p < 0.001) and a greater decrement of the late enhancement (-44.6±25.2 vs. -18.7±27.9 respectively, p = 0.003) compared to that of the PTCs.
      Conclusion: FTCs had a tendency to be observed on neck CT as well-defined, smooth, round to oval nodules with strong early enhancement and a definite decrement of late enhancement as compared to the PTCs.
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      Purpose: The purpose of this study is to analyze the computed tomography (CT) features of follicular thyroid carcinoma (FTC) as compared to those of papillary thyroid carcinoma (PTC) to identify the characteristic imaging features of FTC. Materials an...

      Purpose: The purpose of this study is to analyze the computed tomography (CT) features of follicular thyroid carcinoma (FTC) as compared to those of papillary thyroid carcinoma (PTC) to identify the characteristic imaging features of FTC.
      Materials and Methods: The following CT features were analyzed to compare FTCs (n = 17) and PTCs (n = 27): size, shape, margin, internal composition, calcification, enhancement homogeniety, extrathyroidal extension, lymph node (LN) metastasis and the density and degree of enhancement (qualitatively and quantitatively).
      Results: There were no significant differences between the patients with FTCs and those with PTCs with respect to age and gender, and the internal composition, calcification and enhancement homogeneity of the tumor. However, the FTCs tend to show a larger size (32 mm vs. 15 mm; respectively, p < 0.001), a round to oval shape (52.9% vs. 14.8% respectively, p = 0.001), a well-defined smooth margin (58.8% vs. 14.8% respectively, p = 0.009), less extrathyroidal extension (11.8% vs. 51.9% respectively, p = 0.007) and less LN metastasis (0% vs. 29.6% respectively, p = 0.016) compared to that of the PTCs. Furthermore, the FTCs showed significantly stronger enhancement in the early phase (146.4±42.4 vs. 98.5±38.2 respectively, p < 0.001) and a greater decrement of the late enhancement (-44.6±25.2 vs. -18.7±27.9 respectively, p = 0.003) compared to that of the PTCs.
      Conclusion: FTCs had a tendency to be observed on neck CT as well-defined, smooth, round to oval nodules with strong early enhancement and a definite decrement of late enhancement as compared to the PTCs.

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      참고문헌 (Reference)

      1 정진향, "초음파를 이용한 갑상선 결절의 감별 진단" 대한외과학회 70 (70): 349-356, 2006

      2 Sillery JC, "Thyroid follicular carcinoma: sonographic features of 50 cases" 194 : 44-54, 2010

      3 Sillery JC, "Thyroid follicular carcinoma: sonographic features of 50 cases" 194 : 44-54, 2010

      4 Yoon DY, "The Prevalence and Significance of Incidental Thyroid Nodules Identified on Computed Tomography" JCAT 32 : 810-815, 2008

      5 Lang BH, "Staging systems for follicular thyroid carcinoma: application to 171 consecutive patients treated in a tertiary referral centre" 14 : 29-42, 2007

      6 Shetty SK, "Significance of incidental thyroid lesions detected on CT: correlation among CT, sonography, and pathology" 187 : 1349-1356, 2006

      7 Smith RB, "Preoperative FDG-PET imaging to assess the malignant potential of follicular neoplasms of the thyroid" 138 : 101-106, 2008

      8 Kondo T, "Pathogenetic mechanisms in thyroid follicular-cell neoplasia" 6 : 292-306, 2006

      9 Talbot JN, "PET in thyroid cancers" 35 : 1377-1385, 2006

      10 Ponikiewska D, "Oxyphilic and follicular thyroid tumors: the correlation between the cytopathologic diagnosis and the histopathologic examination" 57 (57): 7-11, 2006

      1 정진향, "초음파를 이용한 갑상선 결절의 감별 진단" 대한외과학회 70 (70): 349-356, 2006

      2 Sillery JC, "Thyroid follicular carcinoma: sonographic features of 50 cases" 194 : 44-54, 2010

      3 Sillery JC, "Thyroid follicular carcinoma: sonographic features of 50 cases" 194 : 44-54, 2010

      4 Yoon DY, "The Prevalence and Significance of Incidental Thyroid Nodules Identified on Computed Tomography" JCAT 32 : 810-815, 2008

      5 Lang BH, "Staging systems for follicular thyroid carcinoma: application to 171 consecutive patients treated in a tertiary referral centre" 14 : 29-42, 2007

      6 Shetty SK, "Significance of incidental thyroid lesions detected on CT: correlation among CT, sonography, and pathology" 187 : 1349-1356, 2006

      7 Smith RB, "Preoperative FDG-PET imaging to assess the malignant potential of follicular neoplasms of the thyroid" 138 : 101-106, 2008

      8 Kondo T, "Pathogenetic mechanisms in thyroid follicular-cell neoplasia" 6 : 292-306, 2006

      9 Talbot JN, "PET in thyroid cancers" 35 : 1377-1385, 2006

      10 Ponikiewska D, "Oxyphilic and follicular thyroid tumors: the correlation between the cytopathologic diagnosis and the histopathologic examination" 57 (57): 7-11, 2006

      11 Lo CY, "Follicular thyroid carcinoma: the role of histology and staging systems in predicting survival" 242 : 708-715, 2005

      12 Lin JD, "Follicular thyroid carcinoma: from diagnosis to treatment" 53 : 441-448, 2006

      13 Lee B, "Follicular thyroid carcinoma metastasis to the esophagus detected by 18FDG PET/CT" 18 : 267-271, 2008

      14 Carling T, "Follicular neoplasms of the thyroid: what to recommend" 15 : 583-587, 2005

      15 Oertel YC, "Follicular lesions of the thyroid gland: from hyperplasia to neoplasia" 14 : 251-252, 2008

      16 Su-kyoung Jeh, "Evaluating the Degree of Conformity of Papillary Carcinoma and Follicular Carcinoma to the Reported Ultrasonographic Findings of Malignant Thyroid Tumor" 대한영상의학회 8 (8): 192-197, 2007

      17 손규리, "Diagnostic Value of CT for the Detection of Cervical Lymph Node Metastases in Papillary Thyroid Carcinoma" 대한영상의학회 60 (60): 383-389, 2009

      18 Miyakawa M, "Diagnosis of thyroid follicular carcinoma by the vascular pattern and velocimetric parameters using high resolution pulsed and power Doppler ultrasonography" 52 : 207-212, 2005

      19 Fukunari N, "Clinical evaluation of color Doppler imaging for the differential diagnosis of thyroid follicular lesions" 28 : 1261-1265, 2004

      20 Choi YJ, "Clinical and ultrasound features of cytology diagnosed follicular neoplasm" 56 : 383-389, 2009

      21 Albores-Saavedra J, "Changing patterns in the incidence and survival of thyroid cancer with follicular phenotype--papillary, follicular, and anaplastic: a morphological and epidemiological study" 18 : 1-7, 2007

      22 Frates MC, "Can color Doppler sonography aid in the prediction of malignancy of thyroid nodules" 22 : 127-131, 2003

      23 Gharib H, "American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules" 12 : 63-102, 2006

      24 AACE/AME Task Force, "American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules" 12 : 63-102, 2006

      25 Paramo JC, "Age, tumor size, and in-office ultrasonography are predictive parameters of malignancy in follicular neoplasms of the thyroid" 14 : 447-451, 2008

      26 Widder S, "A pathologic re-review of follicular thyroid neoplasms: the impact of changing the threshold for the diagnosis of the follicular variant of papillary thyroid carcinoma" 144 : 80-85, 2008

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      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
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      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.1 0.1 0.07
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.06 0.05 0.258 0.01
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