호도약침액의 Nitric Oxide (NO)에 대한 소거효과 = The scavenging effect on nitric oxide (NO) in juglandis semen herbal acupunture solution

다국어 초록 (Multilingual Abstract)

Objectives: Free radical metabolism seems to occupy a remarkably common position in the mechanisms of aging and aging related disease. This study was designed to find out whether Juglandis Semen herbal acupuncture solution (JSHAS) can scavenge Nitric Oxide (NO) or not. Methods: SNAP was used as NO generator. NO concentration was estimated after 2, 6, 12 and 24 hrs in no treatment group, after treatment with Vitamin C or 1, 10, 100㎍/㎖of JSHAS. Results: There was no significant scavenging effect of JSHAS on NO after 2, 6 hrs but significant effect on NO in 10, 100㎍/㎖group after 12hrs. After 24 hrs, there was a significant scavenging effect of JSHAS on NO in 1, 10, 100㎍/㎖group. Conclusions: These results suggest that JSHAS has scavenging effect on NO. This study shows that JSHAS can be used for aging related disease and further studies are required to investigate the antioxidative effects of it.

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