1 Brugnera E, "Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex" 4 : 574-582, 2002
2 Toda S, "Two-step engulfment of apoptotic cells" 32 : 118-125, 2012
3 Ferris RL, "Too much of a good thing? Tim-3 and TCR signaling in T cell exhaustion" 193 : 1525-1530, 2014
4 Nishi C, "Tim4-and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages" 34 : 1512-1520, 2014
5 Tan X, "Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway" 436 : 119-128, 2018
6 Liu W, "Tim-4 in health and disease: friend or Foe?" 11 : 537-, 2020
7 Nakayama M, "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation" 113 : 3821-3830, 2009
8 Flannagan RS, "The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis" 25 : 1511-1522, 2014
9 Park D, "The phosphatidylserine receptor TIM-4 does not mediate direct signaling" 19 : 346-351, 2009
10 Reddien PW, "The engulfment process of programmed cell death in caenorhabditis elegans" 20 : 193-221, 2004
1 Brugnera E, "Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex" 4 : 574-582, 2002
2 Toda S, "Two-step engulfment of apoptotic cells" 32 : 118-125, 2012
3 Ferris RL, "Too much of a good thing? Tim-3 and TCR signaling in T cell exhaustion" 193 : 1525-1530, 2014
4 Nishi C, "Tim4-and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages" 34 : 1512-1520, 2014
5 Tan X, "Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway" 436 : 119-128, 2018
6 Liu W, "Tim-4 in health and disease: friend or Foe?" 11 : 537-, 2020
7 Nakayama M, "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation" 113 : 3821-3830, 2009
8 Flannagan RS, "The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis" 25 : 1511-1522, 2014
9 Park D, "The phosphatidylserine receptor TIM-4 does not mediate direct signaling" 19 : 346-351, 2009
10 Reddien PW, "The engulfment process of programmed cell death in caenorhabditis elegans" 20 : 193-221, 2004
11 Rodriguez-Manzanet R, "The costimulatory role of TIM molecules" 229 : 259-270, 2009
12 Zhu C, "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity" 6 : 1245-1252, 2005
13 Meyers JH, "The TIM gene family regulates autoimmune and allergic diseases" 11 : 362-369, 2005
14 Monney L, "Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease" 415 : 536-541, 2002
15 Jemielity S, "TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine" 9 : e1003232-, 2013
16 Zhang Q, "TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner" 113 : 1484-1492, 2015
17 Meyers JH, "TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation" 6 : 455-464, 2005
18 Chen TT, "TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis" 202 : 955-965, 2005
19 Umetsu SE, "TIM-1 induces T cell activation and inhibits the development of peripheral tolerance" 6 : 447-454, 2005
20 Kobayashi N, "TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells" 27 : 927-940, 2007
21 Su EW, "TIM-1 and TIM-3 proteins in immune regulation" 44 : 9-13, 2008
22 Freeman GJ, "TIM genes : a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity" 235 : 172-189, 2010
23 Lemke G, "TAM receptors and the clearance of apoptotic cells" 1209 : 23-29, 2010
24 Anderson AC, "T-bet, a Th1 transcription factor regulates the expression of Tim-3" 40 : 859-866, 2010
25 DeKruyff RH, "T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells" 184 : 1918-1930, 2010
26 de Souza AJ, "T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase" 180 : 6518-6526, 2008
27 Santiago C, "Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds" 27 : 941-951, 2007
28 Santiago C, "Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family" 26 : 299-310, 2007
29 Shakhov AN, "SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling" 34 : 494-503, 2004
30 He M, "Receptor for advanced glycation end products binds to phosphatidylserine and assists in the clearance of apoptotic cells" 12 : 358-364, 2011
31 Park SY, "Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor" 15 : 192-201, 2008
32 Wong K, "Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages" 107 : 8712-8717, 2010
33 Kinchen JM, "Phagosome maturation : going through the acid test" 9 : 781-795, 2008
34 Wang Y, "Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages" 171 : 331-345, 2017
35 Morioka S, "Living on the Edge : efferocytosis at the Interface of Homeostasis and Pathology" 50 : 1149-1162, 2019
36 Czuczman MA, "Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread" 509 : 230-234, 2014
37 Ichimura T, "Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells" 118 : 1657-1668, 2008
38 Tsai RK, "Inhibition of"self"engulfment through deactivation of myosin-II at the phagocytic synapse between human cells" 180 : 989-1003, 2008
39 Tami C, "Immunoglobulin A(IgA)is a natural ligand of hepatitis A virus cellular receptor 1(HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions" 81 : 3437-3446, 2007
40 Hanayama R, "Identification of a factor that links apoptotic cells to phagocytes" 417 : 182-187, 2002
41 Miyanishi M, "Identification of Tim4 as a phosphatidylserine receptor" 450 : 435-439, 2007
42 McIntire JJ, "Identification of Tapr(an airway hyperreactivity regulatory locus)and the linked Tim gene family" 2 : 1109-1116, 2001
43 Binne LL, "Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals" 178 : 4342-4350, 2007
44 Devitt A, "Human CD14 mediates recognition and phagocytosis of apoptotic cells" 392 : 505-509, 1998
45 Curtiss ML, "Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1(Tim-1)" 48 : 1424-1431, 2011
46 Fadok VA, "Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages" 148 : 2207-2216, 1992
47 Wilker PR, "Evidence for carbohydrate recognition and homotypic and heterotypic binding by the TIM family" 19 : 763-773, 2007
48 Ravichandran KS, "Engulfment of apoptotic cells : signals for a good meal" 7 : 964-974, 2007
49 Doran AC, "Efferocytosis in health and disease" 20 : 254-267, 2020
50 Mazaheri F, "Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia" 5 : 4046-, 2014
51 Savill J, "Corpse clearance defines the meaning of cell death" 407 : 784-788, 2000
52 Park B, "Coreceptors are dispensable for tethering receptor-mediated phagocytosis of apoptotic cells" 6 : e1772-, 2015
53 Park D, "Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein" 477 : 220-224, 2011
54 Segawa K, "Constitutive exposure of phosphatidylserine on viable cells" 108 : 19246-19251, 2011
55 Kumanogoh A, "Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2" 419 : 629-633, 2002
56 Rhein BA, "Characterization of human and murine T-Cell immunoglobulin mucin domain 4(TIM-4)IgV domain residues critical for ebola virus entry" 90 : 6097-6111, 2016
57 Gumienny TL, "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration" 107 : 27-41, 2001
58 De Maeyer RPH, "Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly" 21 : 615-625, 2020
59 Park D, "BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module" 450 : 430-434, 2007
60 Segawa K, "An apoptotic ‘Eat Me’ Signal : phosphatidylserine exposure" 25 : 639-650, 2015
61 Lee J, "A scaffold for signaling of Tim-4-mediated efferocytosis is formed by fibronectin" 26 : 1646-1655, 2019