2주 동안의 율무 추출물 경구 투여가 복강대식세포의 사이토카인 IL-1β, IL-6, TNF-α, IL-10 생성에 미치는 영향 = Effect of Job's Tear(Yul-Moo) Extracts on Mouse Oral Administration IL-1β, IL-6, TNF-α, IL-10 Cytokine Production by Peritoneal Macrophage for Two Weeks

다국어 초록 (Multilingual Abstract)

The present study examined the ex vivo effect of Job's tear on immune function. Seven to eight week old mice(Balb/c) were fed a chow diet ad libitum two different concentrations (50 and 500 ㎎/㎏ BW) of water extract of Job's tear were orally administ every other day for two weeks. The results indicated that macrophage activation had occurred in the mice receiving 50 ㎎/㎏ B. W. of Job's tear water extract. Overall, using a mouse model, this study demonstrated that Job's tear extract may enhance immune function by regulating the IL-1β, IL-6, TNF-α and IL-10 cytokine production capacity of activated macrophages in mice. This study may suggest that supplementation of Job's tear water extracts may enhance the immune function by regulating the enhancing the cytokine production by activated macrophage ex vivo.

참고문헌 (Reference)

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