Cigarette is a kind of favorite product for nicotine inhalation. In the smoke of cigarette, there are 44 kind of known harmful ingredient and they cause various injury for the smokers. Therefore, many smokers tried to stop smoking and they developed m...
Cigarette is a kind of favorite product for nicotine inhalation. In the smoke of cigarette, there are 44 kind of known harmful ingredient and they cause various injury for the smokers. Therefore, many smokers tried to stop smoking and they developed many kind of cigarette substitute. Tobacco companies reduce the nicotine inhalation by adding low nicotine material to the cigarette manufacturing or by punching holes to the cigarette paper and direct adding fresh air to the inhaled smoke. Low nicotine tobacco plant could be developed by selection from natural Nicotiana species, mutation, antisence transformation, RNAi transformation, and homologous recombination. Putrescine N-methyltransferase (PMT) and quinolinate phospho-ribosyltransferase (QPT) could be used for the target points of the modification