Purpose: The purpose of this study was to evaluate the efficacy of Betafoam in terms of wound healing and safety. Methods: Fifty-four male adult Sprague-Dawley rats (weight, 200–250 g) were used in the study. Full-thickness skin defects were crea...
http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
https://www.riss.kr/link?id=A105049079
Eung Jin Shin (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Han Jo Kim (Department of Hematology and Oncology, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Myoung Won Son (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Tae Sung Ahn ; Hyun Yong Lee (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Dae Ro Lim (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Sang Byung Bae (Department of Hematology and Oncology, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Seob Jeon (Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Cheonan, Kor) ; Hyungjoo Kim (Medical Science Research Institute, Soonchunhyang University, Cheonan, Korea) ; Dongjun Jeong (Medical Science Research Institute, Soonchunhyang University, Cheonan, Korea) ; Moon Soo Lee (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea) ; Dong-Sun Kim (Department of Anatomy, Kyungpook National University School of Medicine, Daegu, Korea) ; Jeong Se Noh (Soonchunhyang University College of Medicine, Cheonan, Korea) ; Moo-Jun Baek (Department of Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea)
2018
English
KCI등재,SCOPUS,SCIE
학술저널
19-25(7쪽)
3
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
Purpose: The purpose of this study was to evaluate the efficacy of Betafoam in terms of wound healing and safety. Methods: Fifty-four male adult Sprague-Dawley rats (weight, 200–250 g) were used in the study. Full-thickness skin defects were crea...
Purpose: The purpose of this study was to evaluate the efficacy of Betafoam in terms of wound healing and safety.
Methods: Fifty-four male adult Sprague-Dawley rats (weight, 200–250 g) were used in the study. Full-thickness skin defects were created on the back of each rats. The rats were assigned to 6 groups according to the type of wound dressing used (n = 9 for each group): Betafoam, Allevyn-Ag, Mepilex-Ag, Medifoam silver, Polymem-Ag, and gauze. The wound size, histological findings, and amount of DNA on the changed dressings for each group were analyzed and compared.
Results: All groups showed an effective decrease in wound size. However, the differences between Betafoam and the other dressings were statistically significant on day 14 (P < 0.05). The number of newly generated blood vessels in the Betafoam group was significantly higher than in the gauze, Allevyn-Ag, and Medifoam silver groups (P < 0.001). In the Betafoam group, the proportion of collagen deposition was highest and showed a significantly superior arrangement of collagen fibers compared with the gauze, Allevyn-Ag, Mepilex-Ag, and Medifoam silver groups. The total content of the remaining DNA counts of the exchanged dressings were significantly lower in the Betafoam group than the others.
Conclusion: Betafoam is effective in wound healing and provides the best performance amongst the various types of dressing materials in terms of re-epithelialization, angiogenesis, collagen deposition, and tissue invasion.
목차 (Table of Contents)
참고문헌 (Reference)
1 Guo C, "Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1" 116 : 155-160, 2005
2 Bae SC, "Tumor suppressor activity of RUNX3" 23 : 4336-4340, 2004
3 Li QL, "Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer" 314 : 223-228, 2004
4 Soong R, "The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome" 100 : 676-679, 2009
5 Levanon D, "Runx3 knockouts and stomach cancer" 4 : 560-564, 2003
6 Chi XZ, "RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD" 25 : 8097-8107, 2005
7 Nishio M, "RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker" 30 : 2673-2682, 2010
8 Torquati A, "RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells" 136 : 310-316, 2004
9 Ito Y, "RUNX transcription factors as key targets of TGF-beta superfamily signaling" 13 : 43-47, 2003
10 Ozaki T, "RUNX family participates in the regulation of p53-dependent DNA damage response" 2013 : 271347-, 2013
1 Guo C, "Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1" 116 : 155-160, 2005
2 Bae SC, "Tumor suppressor activity of RUNX3" 23 : 4336-4340, 2004
3 Li QL, "Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer" 314 : 223-228, 2004
4 Soong R, "The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome" 100 : 676-679, 2009
5 Levanon D, "Runx3 knockouts and stomach cancer" 4 : 560-564, 2003
6 Chi XZ, "RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD" 25 : 8097-8107, 2005
7 Nishio M, "RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker" 30 : 2673-2682, 2010
8 Torquati A, "RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells" 136 : 310-316, 2004
9 Ito Y, "RUNX transcription factors as key targets of TGF-beta superfamily signaling" 13 : 43-47, 2003
10 Ozaki T, "RUNX family participates in the regulation of p53-dependent DNA damage response" 2013 : 271347-, 2013
11 Ku JL, "Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines" 23 : 6736-6742, 2004
12 Kato N, "Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants" 163 : 387-391, 2003
13 박원상, "Hypermethylation of the RUNX3 gene in hepatocellular carcinoma" 생화학분자생물학회 37 (37): 276-281, 2005
14 Xiao WH, "Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma" 10 : 376-380, 2004
15 Nakase Y, "Frequent loss of RUNX3 gene expression in remnant stomach cancer and adjacent mucosa with special reference to topography" 92 : 562-569, 2005
16 Oshimo Y, "Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma" 71 : 137-143, 2004
17 Osaki M, "Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinoma" 34 : 605-612, 2004
18 Lao VV, "Epigenetics and colorectal cancer" 8 : 686-700, 2011
19 Goel A, "Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers" 112 : 754-759, 2004
20 Fukushige S, "DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers" 229 : 173-185, 2013
21 Ogino S, "CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma" 450 : 529-537, 2007
22 Mu WP, "Clinical significance and association of RUNX3 hypermethylation frequency with colorectal cancer: a meta-analysis" 7 : 1237-1245, 2014
23 Li QL, "Causal relationship between the loss of RUNX3 expression and gastric cancer" 109 : 113-124, 2002
24 Siegel R, "Cancer statistics, 2014" 64 : 9-29, 2014
Brain metastasis from colorectal cancer
Technique for orthotopic liver transplantation in cynomolgus monkeys (Macaca fascicularis)
Surgery of multiple lymphangioma in small bowel
학술지 이력
연월일 | 이력구분 | 이력상세 | 등재구분 |
---|---|---|---|
2023 | 평가예정 | 해외DB학술지평가 신청대상 (해외등재 학술지 평가) | |
2020-11-12 | 학술지명변경 | 한글명 : 대한외과학회지 -> Annals of Surgical Treatment and Research | |
2020-01-01 | 평가 | 등재학술지 유지 (해외등재 학술지 평가) | |
2013-12-30 | 학술지명변경 | 외국어명 : Journal of The Korean Surgical Society -> Annals of Surgical Treatment and Research | |
2011-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2009-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2006-01-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
2005-01-01 | 평가 | 등재후보 1차 PASS (등재후보1차) | |
2004-01-01 | 평가 | 등재후보학술지 유지 (등재후보1차) | |
2002-07-01 | 평가 | 등재후보학술지 선정 (신규평가) |
학술지 인용정보
기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
---|---|---|---|
2016 | 1.39 | 0.21 | 0.97 |
KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
0.73 | 0.56 | 0.328 | 0.06 |