Cost of supplying umbilical cord blood for hematopoietic stem cell transplantation

다국어 초록 (Multilingual Abstract)

Background: To analyze unit cost of umbilical cord blood (UCB) for hematopoietic stem cell transplantation (HSC) and to proposed a method for cost-effective supply of UCB. Study Design and Methods: “Activity Based Costing” (ABC) was adopted to calculate the supplying cost of a UCB unit. The cost object is UCB supplying cost, and activity center a UCB bank. To identify activities of UCB supply, literature and regulations were reviewed with consultation by experts. The survey was conducted on 16 banks to identify cost by each activity. Results: The total cost of supplying UCB was $32,781,133 and the unit cost $ 964 that was separable into one-off cost ($ 924/unit) and continuous cost ($ 40/unit). Banks with large inventory had lower supplying cost. Banks storing 10,000 units or greater had lower cost than its counterparts ($ 777 vs $ 2,078, respectively). Conclusion: Considering unit cost is widely different among banks, it is essential that supplying of UCB is carried out efficiently. An inverse association between cost and inventory size suggests integration of small banks into large ones, or a centralized banking system, are advantageous in terms of cost.

참고문헌 (Reference)

1 윤호순, "종합병원 일반병동 간호행위의 활동기준원가분석" 간호행정학회 19 (19): 449-461, 2013

2 이영호, "제대혈－현황과 전망" 대한혈액학회 42 (42): 1-1, 2007

3 신수, "국내 제대혈이식 및 기증제대혈은행 현황" 대한수혈학회 24 (24): 103-110, 2013

4 Health Insurance Review & Assessment Service (HIRA), "The manual of RBRVS development for clinical practice expert panels" Health Insurance Review & Assessment Service 2013

5 NHS blood and transplant (NHSBT), "The future unrelated donor stem cell transplantation in the UK" 1-96, 2010

6 Ministry of Health and Welfare (MOHW), "Regulation of review and assessment for the management of cord blood"

7 The Korean Society for Laboratory Medicine (KSLM), "Laboratory medicine" Beommoon Education Press 966-, 2014

8 Bart, T., "Impact of selection of cord blood units from the United States and Swiss registries on the cost of banking operations" 40 (40): 14-20, 2013

9 Ministry of Health and Welfare (MOHW), "Decrease in medical expenses for public cord blood transplant patients from October 1, 2014"

10 Lee, M. N., "Current Status and Management of Cord Blood Banks in South Korea" Korea Centers for Disease Control and Prevention 7 (7): 509-513, 2014

11 Kaimal, A. J., "Cost-effectiveness of private umbilical cord blood banking" 114 (114): 848-855, 2009

12 Sirchia, G., "Cost of umbilical cord blood units released for transplantation" 39 (39): 645-650, 1999

13 Lee, Y. H., "Analysis of stored and transplanted cord blood units from Korea Cord : Reappraisal of banking guidelines and selection stratagem" 53 (53): 123-127, 2013

14 Wagner, J. E., "Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease" 346 (346): 214-219, 1995

15 Ben-Arieh, D., "Activity-based cost management for design and development stage" 83 (83): 169-183, 2003