We designed novel zwitterionic and tetra-fluorinated polyurethane (ZFPU) additives to confer anti-fouling and anti-thrombotic effects and blended these with polyvinyl chloride (PVC). 1HNMR and FTIR analyses showed that the zwitterionic groups and fluo...
We designed novel zwitterionic and tetra-fluorinated polyurethane (ZFPU) additives to confer anti-fouling and anti-thrombotic effects and blended these with polyvinyl chloride (PVC). 1HNMR and FTIR analyses showed that the zwitterionic groups and fluorinated groups were successfully introduced onto the ZFPU backbone. We also investigated the protein adsorption, platelet adhesion and wettability of additivesblended PVC films. Our results demonstrated that the ZFPU additivesblended PVC surfaces significantly suppressed protein adsorption and platelet adhesion than those of pristine PVC surface. Based on these results, it is expected that our novel additives will be promising for various biomaterials, including blood-contacting medical devices.